Protein C News and Research

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Gene deletion in wheat lowers allergenic proteins while maintaining bread quality

Wheat is a major source of calories, carbohydrates and protein worldwide, and its distinctive gluten proteins are what gives bread and pasta dough texture and elasticity.

5 May 2025

Breakthrough in labeling TB glycans could lead to faster diagnosis

Tuberculosis, the world's deadliest infectious disease, is estimated to infect around 10 million people each year, and kills more than 1 million annually. Once established in the lungs, the bacteria's thick cell wall helps it to fight off the host immune system.

5 May 2025

Disrupted muscle clocks linked to accelerated aging in shift workers

Muscle cells contain their own circadian clocks and disrupting them with shift work can have a profound impact on aging, according to new research.

5 May 2025

A decade of discovery in the science of healthy aging and human longevity

It's notable when a scientific study reaches the decade mark, but when the topic is the healthy aging of people who have lived 10 times as long, it just means there's still a lot more to learn.

5 May 2025

New rifamycin drugs fight antibiotic-resistant lung infections more effectively

Researchers have developed next-generation rifamycin analogs that effectively kill both replicating and nonreplicating Mycobacterium abscessus while minimizing drug-drug interactions. Lead candidates UMN-120 and UMN-121 showed superior efficacy to current treatments in mouse models and retained potency against M. tuberculosis.

5 May 2025

Scientists use AI to build mutation-proof antibodies for SARS-CoV-2

Researchers used AI models to design antibodies that neutralize over 1,300 SARS-CoV-2 strains, including Delta and Omicron. The models demonstrated faster, cheaper, and more adaptable therapeutic development compared to traditional methods.

5 May 2025

Boosting glucose metabolism in glial cells reduces neurodegeneration in fruit flies

Researchers from Tokyo Metropolitan University have discovered that impaired glucose metabolism in glial cells, a type of cell in our nervous system, plays a key role in the degeneration caused by Alzheimer's disease.

5 May 2025

Advancing benzodiazepine detection for toxicology

Learn how experts are advancing benzodiazepine analysis and detection using insights from the lab.

From Waters Advanced Diagnostics 5 May 2025

Researchers unravel the genetic contributions to familial Alzheimer's disease development

A group of researchers in the lab of Prof. Lucía Chávez Gutiérrez (VIB-KU Leuven) have unraveled the genetic contributions to familial Alzheimer's Disease development and revealed how specific mutations act as a clock to predict the disease age of onset.

5 May 2025

The Surgeon-Scientist Pioneering Regenerative Engineering

In this interview, Sir Prof. Cato T. Laurencin, the 2025 Coulter Lecturer, discusses how he is addressing today’s medical challenges using the technology of the future.

From Pittcon 5 May 2025

Semaglutide clears liver inflammation and cuts fibrosis in MASH patients, trial shows

A phase 3 trial shows that once-weekly semaglutide significantly improves liver histology in patients with metabolic dysfunction-associated steatohepatitis (MASH). The interim results also reveal meaningful weight loss and improved cardiometabolic markers, with a favorable safety profile.

4 May 2025

RNA editing enzyme found to trigger neuroinflammation in Parkinson's

Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage.

3 May 2025

Are one-year-olds in Australia eating right? New study reveals nutrient gaps

A study from the ORIGINS cohort in Western Australia assessed the diets of one-year-old children, comparing intake to national guidelines. While most nutrient targets were met, key shortfalls in iodine and excessive sodium intake raised concerns, especially for breastfed infants.

2 May 2025

Heat triggers sperm activation for fertilization in mammals

In mammals - including us humans - sperm are surprisingly picky about temperature, thriving best in conditions a few degrees cooler than normal body temperature.

2 May 2025

HO-1 regulates liver fibrosis in NAFLD through the SIRT1 TGF-β Smad3 pathway

Heme oxygenase 1 (HO-1) has an influential yet insufficiently investigated effect on Sirtuin 1 (SIRT1), a histone deacetylase activated by nicotinamide adenine dinucleotide, which may impact the transforming growth factor-β (TGF-ß)/Smad3 pathway in nonalcoholic fatty liver disease (NAFLD)-related liver fibrosis.

2 May 2025

New albumin-based vaccine shows promise for mucosal immunity

Vaccines save millions of lives every year, but there is still an urgent need for more efficient vaccines. Strategies to combat serious outbreaks of viral infections are particularly important.

2 May 2025

ZIP4 protein identified as driver of glioblastoma aggression

In a study published Wednesday in the Proceedings of the National Academy of Sciences (PNAS), University of Oklahoma researchers detail their discoveries about why the brain tumor glioblastoma is so aggressive.

2 May 2025

Gut immune cells linked to worsening rheumatoid arthritis

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

2 May 2025

Retinal exams show promise for early detection of Parkinson's disease

Could it be possible to diagnose Parkinson's disease with the help of a simple retinal exam? The idea should be seriously considered, according to a study published in the May issue of Neurobiology of Disease by researchers from Université Laval who discovered that the retina of people with Parkinson's disease responds differently to light stimuli than that of healthy people.

1 May 2025

Exploring the relationship between mitochondrial quality control mechanisms and atherosclerosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mitochondrial quality control (MQC) mechanisms - including biogenesis, dynamics, mitophagy, proteostasis, the unfolded protein response, and mitochondrial-derived vesicles - play critical roles in the development of atherosclerosis.

1 May 2025