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Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy

Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare.

13 Mar 2026

BSO mimics anti-obesity effects without causing bone loss in mice

A new research paper was published in Volume 18 of Aging-US on March 2, 2026, titled "D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice."

13 Mar 2026

Review examines clinical trial phases in drug development

Announcing a new article publication for BIO Integration journal. Clinical trials bridge basic research and clinical application, serving as essential steps in drug development.

13 Mar 2026

Defining the limits of immunotherapy in early small-cell lung cancer

Immunotherapy given during and after chemoradiation did not improve survival for study participants with limited-stage, small-cell lung cancer (SCLC) according to the results of an international clinical trial, NRG-LU005, led by NRG Oncology in collaboration with the Alliance for Clinical Trials in Oncology. The results are published in the Journal of Clinical Oncology.

13 Mar 2026

Experimental therapy eliminates pancreatic precancerous cells in mice study

A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.

12 Mar 2026

Topical cream activates immune response to suppress skin cancer growth

A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, according to a study published today in the Journal of Clinical Investigation.

12 Mar 2026

High fat diets allow gut bacteria to enter the brain via the vagus nerve

With more than 100 million neurons in the digestive tract, the gut is commonly known as the "second brain" in numerous cultures, including ancient Greece, Japan, China and India, linking digestion with physical and mental well-being.

12 Mar 2026

Japanese study evaluates sleep architecture and safety of common insomnia drugs

OSA is a common sleep disorder characterized by oxygen desaturation due to repeated airway collapse during sleep.

12 Mar 2026

Personalized counseling program helps cervical cancer survivors quit smoking

A new study led by UCLA researchers suggests that a personalized counseling program can significantly help women who have survived cervical precancer or cervical cancer to quit smoking - and does so at a cost that researchers say represents good value for healthcare systems.

12 Mar 2026

New study identifies specific brain cells most vulnerable to ALS and dementia

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) belong to a spectrum of neurodegenerative diseases with overlapping symptoms, characterized by muscle wasting, paralysis, dementia, and other serious impairments.

12 Mar 2026

The 0.05 EU/mg breakthrough: How Sino Biological ProPure™ is redefining the Ultra-Low Endotoxin standard

When we discuss bacterial infections, we often think of exotoxins—those soluble proteins actively secreted by bacteria—while overlooking endotoxins, which are more insidious but equally dangerous.

From Sino Biological Inc. 12 Mar 2026

Study links prior authorization to delayed heart failure prescriptions

Prior authorization, a process that requires physicians to obtain approval from health care insurers before certain treatments are covered, may keep patients from filling prescriptions for two critical heart failure drugs, a new study shows.

12 Mar 2026

Decoding the neighborhood dynamics of childhood brain cancer

New research published in Nature finds that tumor cells within supratentorial ependymomas (SE) – an aggressive childhood brain cancer – cluster into distinct tumor cell populations. Much like a neighborhood in your hometown, each cell subtype within these "communities" has a specific (and previously unappreciated) role to play.

12 Mar 2026

New protein target for safer lung cancer therapy

Researchers at the University of Gothenburg have identified a protein linked to an increased risk of metastasis and recurrence in lung cancer. The findings are presented in a study that paves the way for new precision medicine approaches, particularly for older patients.

12 Mar 2026