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Iressa (gefinitib) chemotherapy combination proves safe for head and neck cancer patients

Patients undergoing treatment for advanced head and neck cancers may respond well to the addition of gefinitib to chemotherapy, according to a study sponsored by the Eastern Cooperative Oncology Group and chaired by Ethan Argiris, M.D., associate professor of medicine, University of Pittsburgh School of Medicine, and co-leader of the Head and Neck Cancer Program of the University of Pittsburgh Cancer Institute (UPCI).

31 May 2009

Blood-pressure medicine shown to reverse the effects of early-stage liver failure

Newcastle University researchers analysed a small clinical trial of losartan, a drug normally prescribed for hypertension, on 14 patients in Spain, who had Hepatitis C.

31 May 2009

New ultra-sensitive device detects viruses in minutes

Imagine being able to detect in just a few minutes whether someone is infected with a virus. This has now become a reality, thanks to a new ultra-sensitive detector that has been developed by Ostendum, a spin-off company of the University of Twente.

28 May 2009

The neurobiology of music perception and production related to the pathways affecting intrinsic attachment behavior?

Music is social communication between individuals - humming of lullabies attach infant to parent and singing or playing music adds croup cohesion. The neurobiology of music perception and production is likely to be related to the pathways affecting intrinsic attachment behavior, suggests a resent Finnish study. The study gives new information about genetic background of musical aptitude.

26 May 2009

Cancer drugs erlotinib and gefitinib might treat alcoholism

A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That's the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects' response to alcohol.

22 May 2009

African-American women breast cancer sufferers often refuse chemotherapy and radiation therapy

A new study finds that nearly one in four African American women with late stage breast cancer refused chemotherapy and radiation therapy, potentially life saving therapies.

22 May 2009

Research suggests role of low vitamin D in cancer

In studying the preventive effects of vitamin D, researchers at the Moores Cancer Center at the University of California, San Diego, have proposed a new model of cancer development that hinges on a loss of cancer cells' ability to stick together. The model, dubbed DINOMIT, differs substantially from the current model of cancer development, which suggests genetic mutations as the earliest driving forces behind cancer.

22 May 2009

Study offers new insights into morphine-induced tolerance and increased pain sensitivity

A study published in the June issue of Anesthesiology has shown that a drug metabolite of the opioid morphine may be a key factor in the paradoxical increased sensitivity to pain caused by chronic morphine use. For the first time, this metabolite (called morphine-6 glucuronide, or M6G) was shown to act independently of the pain receptors typically targeted during morphine administration.

21 May 2009

Genetic signature predicts clinical outcomes in certain types of breast cancer

Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer.

19 May 2009

Protein neuregulin 1 critical to insulating the body's wiring could also become treatment target

A new protein identified as critical to insulating the wiring that connects the brain and body could one day be a treatment target for divergent diseases, from rare ones that lower the pain threshold to cancer, Medical College of Georgia researchers say.

19 May 2009

Many low-income women breast cancer patients skipping hormonal therapy, lowering their survival rates

Many low-income women are failing to take the hormonal therapy prescribed as part of their breast cancer treatment, possibly lowering their survival rates, according to a study led by a researcher in the Duke Comprehensive Cancer Center.

18 May 2009

Computer simulation captures immune response to flu

Researchers have successfully tested first the first time a computer simulation of major portions of the body's immune reaction to influenza type A, with implications for treatment design and preparation ahead of future pandemics, according to work accepted for publication, and posted online, by the Journal of Virology.

18 May 2009

Pazopanib shows promise for aggressive thyroid cancer

A medication that helps stop the growth of new blood vessels has produced dramatic benefits for some patients with aggressive thyroid cancer, research from Mayo Clinic indicates.

17 May 2009

A relationship found between cancer stem cells and prognosis in primary breast cancer

Breast cancer patients who received chemotherapy prior to surgery had heightened levels of cancer-initiating stem cells in their bone marrow, and the level of such cells correlated to a tumor's lymph node involvement, according to research from The University of Texas M. D. Anderson Cancer Center.

15 May 2009

Common gene variation explains why some women may find it more difficult to quit smoking during pregnancy

Researchers from the Peninsula Medical School and the University of Bristol, using data from the Avon Longitudinal Study of Parents and Children and the Exeter Family Study of Childhood Health, have identified a common genetic variant that explains why some women may find it more difficult to quit smoking during pregnancy.

15 May 2009

Determining success or failure in cholesterol-controlling drugs

Researchers at the University of California, San Diego have discovered that a complex network of interactions between drugs and the proteins with which they bind can explain adverse drug effects. Their findings suggest that adverse drug effects might be minimized by using single or multiple drug therapies in order to fine-tune multiple off-target interactions.

15 May 2009

Discovery of molecule ‘superfamily’ that causes melanoma apread

A University of Nebraska Medical Center research team has determined that a superfamily of molecules holds the secret to the progression and spread of melanoma -- the deadliest form of skin cancer. The study results were published in the May 13 of the British Journal of Cancer.

13 May 2009

Molecular superfamily causes melanoma spread

Molecular superfamily causes melanoma spread A superfamily of molecules holds the secret to the development and spread of melanoma - the deadliest form of skin cancer, revealed a study published in the British Journal of Cancer.

13 May 2009

Break through in the treatment of bacterial meningitis

It can take just hours after the symptoms appear for someone to die from bacterial meningitis. Now, after years of research, experts at The University of Nottingham have finally discovered how the deadly meningococcal bacteria is able to break through the body's natural defence mechanism and attack the brain.

13 May 2009

Building a bridge from Alzheimer's disease to diabetes and vice versa

Modern societies face the increasing burden of age-related diseases, in particular Alzheimer's disease (AD) and type 2 diabetes (T2D).

12 May 2009

Receptor News and Research

Iressa (gefinitib) chemotherapy combination proves safe for head and neck cancer patients

Blood-pressure medicine shown to reverse the effects of early-stage liver failure

New ultra-sensitive device detects viruses in minutes

The neurobiology of music perception and production related to the pathways affecting intrinsic attachment behavior?

Cancer drugs erlotinib and gefitinib might treat alcoholism

African-American women breast cancer sufferers often refuse chemotherapy and radiation therapy

Research suggests role of low vitamin D in cancer

Study offers new insights into morphine-induced tolerance and increased pain sensitivity

Genetic signature predicts clinical outcomes in certain types of breast cancer

Protein neuregulin 1 critical to insulating the body's wiring could also become treatment target

Many low-income women breast cancer patients skipping hormonal therapy, lowering their survival rates

Computer simulation captures immune response to flu

Pazopanib shows promise for aggressive thyroid cancer

A relationship found between cancer stem cells and prognosis in primary breast cancer

Common gene variation explains why some women may find it more difficult to quit smoking during pregnancy

Determining success or failure in cholesterol-controlling drugs

Discovery of molecule ‘superfamily’ that causes melanoma apread

Molecular superfamily causes melanoma spread

Break through in the treatment of bacterial meningitis

Building a bridge from Alzheimer's disease to diabetes and vice versa

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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