Immune System News and Research

RSS

Phase I clinical study of Selexys SelG1 for sickle cell disease completed

Selexys Pharmaceuticals announced today that it has completed a Phase I clinical study of its lead compound SelG1, an antibody specific for the pro-inflammatory cell adhesion molecule P-selectin.

19 Dec 2011

Bloomberg TV to air segment on Antigen Express' immunotherapeutic breast cancer vaccine

Generex Biotechnology Corporation today announced that Bloomberg Television is scheduled to air a segment on the immunotherapeutic breast cancer vaccine being developed by its wholly-owned subsidiary, Antigen Express, Inc.

19 Dec 2011

Link between malaria and salmonella infections

The link between malaria and salmonella infections has been explained for the first time, opening the way to more effective treatments.

19 Dec 2011

Immediate ART appears preferable to deferring treatment among recently infected HIV patients

Among people recently infected with HIV, immediate antiretroviral therapy (ART) appears preferable to deferring treatment, according to a new study published in The Journal of Infectious Diseases and now available online.

17 Dec 2011

Behavioral interventions reduce STIs and improve condom use

Behavioral interventions aimed at reducing sexual risk behaviors, such as unprotected sex, are effective at both promoting condom use and reducing sexually transmitted infections (STIs) long after the initial intervention, according to a new report in the December 15 issue of the Journal of Acquired Immune Deficiency Syndromes.

16 Dec 2011

Scientists identify how cells reduce tissue damage from inflammation in ALI model

Researchers at the University of Illinois at Chicago College of Medicine have found in an animal model of acute lung injury a molecular mechanism that allows cells of the immune system to reduce tissue damage from inflammation.

16 Dec 2011

HIV testing remains important amid push for expanded treatment in Africa

"With a needle puncture on your finger and a drop of blood, the magic of modern science can give you a rapid HIV test in seconds, and so, knowing your status, you are better able to negotiate the rocky road of surviving HIV where timely detection is key," Farai Sevenzo, a columnist and filmmaker, writes in this BBC News opinion piece, part of a series from African journalists.

16 Dec 2011

Lab results change in consistent ways during the course of Kawasaki disease

Children with Kawasaki disease show a pattern of changing laboratory test results as the disease runs its course, according to a study in the December issue of The Pediatric Infectious Disease Journal.

15 Dec 2011

Cereblon protein now holds hope in fight against multiple myeloma

Research on the same protein that was a primary mediator of the birth defects caused by thalidomide now holds hope in the battle against multiple myeloma, say Mayo Clinic researchers who presented results of several clinical trials at the 53nd annual meeting of the American Society of Hematology Dec. 10-13 in San Diego.

15 Dec 2011

GeneKey launches personalized medicine service for cancer patients

GeneKey Corp., announced today that it has launched a personalized medicine service that empowers cancer patients and their oncology teams to develop treatment strategies based on insight into the biology of individual tumors.

15 Dec 2011

JHN to initiate new Phase I immunotherapy trial in glioblastoma

Physicians at the Jefferson Hospital for Neuroscience (JHN), the region's only dedicated hospital for neuroscience, are tackling a particularly aggressive brain cancer that even surgery, chemotherapy and radiation often fail to treat with a promising new immunotherapy to attack a patient's tumor with their own cancer cells.

15 Dec 2011

Nitroglycerin can boost body's natural immune response to cancer

Researchers at Queen's University have identified a new mechanism that could potentially explain why the body's immune system sometimes fails to eliminate cancer. The new findings shed light on the possible cause of immune resistance in cancer cells, and indicate that nitroglycerin, a relatively safe and low-cost drug used for more than a century to treat angina, may be effective for managing certain cancers.

15 Dec 2011

Researchers develop mouse model to investigate fenugreek allergy

A mouse model to investigate allergy to fenugreek has been developed by Norwegian researchers. The model can also be used to study cross-reactivity to peanut, soy and lupin, major food allergens with public health relevance.

15 Dec 2011

Fresh cells can pep talk immune cells exhausted by HIV or hepatitis C

Chronic infections by viruses such as HIV or hepatitis C eventually take hold because they wear the immune system out, a phenomenon immunologists describe as exhaustion.

14 Dec 2011

Potential nanoparticle treatment for macular degeneration and retinitis pigmentosa

Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, the Mayo Clinic and Johns Hopkins Medicine shows that steroids attached to the dendrimers targeted the damage-causing cells associated with neuroinflammation, leaving the rest of the eye unaffected and preserving vision.

14 Dec 2011

Researchers discover how statins promote breakdown of plaque in arteries

In a new study, NYU Langone Medical Center researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The study was published online by the journal PLoS One on December 6, 2011.

14 Dec 2011

Maraviroc reduces incidence of GvHD in blood cancer patients after ASCT

An HIV drug that redirects immune cell traffic appears to significantly reduce the dangerous complication graft-versus-host disease (GvHD) in blood cancer patients following allogeneic stem cell transplantation (ASCT), according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting.

14 Dec 2011

Macrophages play a role in brown fat metabolism

Throughout the interior spaces of humans and other warm-blooded creatures is a special type of tissue known as brown fat, which may hold the secret to diets and weight-loss programs of the future.

14 Dec 2011

Researchers create vaccine that reduces tumors in mice

Researchers at Mayo Clinic in Arizona and the University of Georgia (UGA) have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases - including those that are resistant to common treatments.

14 Dec 2011

Aethlon Hemopurifier can capture Nef protein exosomes linked with HIV

Aethlon Medical, Inc., the pioneer in developing therapeutic filtration devices to address infectious disease and cancer, announced today that researchers have discovered that the Aethlon Hemopurifier is able to capture particles known as Nef protein exosomes, which contribute to the progression of human immunodeficiency virus (HIV) infection to acquired immunodeficiency syndrome.

14 Dec 2011