Immune System News and Research

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New type of cancer immunotherapy harnesses body's immune system to attack tumors

By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses.

19 Aug 2013

Powerful mechanism helps viruses evade body's immune response

Researchers at the Salk Institute for Biological Studies have discovered a powerful mechanism by which viruses such as influenza, West Nile and Dengue evade the body's immune response and infect humans with these potentially deadly diseases. The findings may provide scientists with an attractive target for novel antiviral therapies.

19 Aug 2013

Arrays of nanoscale sensors detect flaws in drugs and help improve production

MIT chemical engineers have discovered that arrays of billions of nanoscale sensors have unique properties that could help pharmaceutical companies produce drugs - especially those based on antibodies - more safely and efficiently.

17 Aug 2013

Dermatology researcher receives NIH grant to investigate role of nervous system in psoriasis

Dermatology researcher Nicole Ward, PhD, has earned her third National Institutes of Health grant in a year - including two that scored in the first percentile. With this most recent award, an R21, she will investigate the role the nervous system plays in psoriasis - an inflammatory autoimmune disease characterized by raised areas of red, scaly, itchy and sometimes painful patches of skin.

17 Aug 2013

Pre-doctoral students receive International Student Research Fellowships from HHMI

The Howard Hughes Medical Institute has awarded two doctoral students from the Sackler School of Graduate Biomedical Sciences at Tufts University with 2013 International Student Research Fellowships. Seblewongel Asrat, from Ethiopia, studies the bacterium that causes Legionnaires' disease while Jennifer Nwankwo, from Nigeria, studies red blood cell dehydration in sickle cell disease.

17 Aug 2013

Study shows lymph node location influences maturation process of cells they contain

Based on their observations, the scientists deduced that lymph node location influences the maturation process of the cells they contain. "The cells retained their original skills for weeks following the transplant," says Dr. Sascha Cording, one of the study's first authors. "You might say lymph nodes have something like a location-specific memory."

17 Aug 2013

GHI research aims to target breast cancer stem-like cells using immunotherapy

New hope is on its way for the fight against breast cancer as Griffith Health Institute research aims to target the disease with immune-based therapies.

16 Aug 2013

Phase II trial to investigate vaccine therapy combined with Avastin for patients with recurrent GBM

Northwestern Medicine- recently joined a landmark clinical trial to investigate if a vaccine made from a patient's own brain tumor is effective in slowing tumor progression and extending survival.

16 Aug 2013

Research: MRSA in humans originated in cattle at least 40 years ago

A type of MRSA found in humans originated in cattle at least 40 years ago, new research has found. The study provides clear evidence that livestock were the original source of an MRSA strain which is now widespread in people.

16 Aug 2013

Researchers discover how common oral bacterium can contribute to colorectal cancer

Researchers from Case Western Reserve University School of Dental Medicine have discovered how a common oral bacterium can contribute to colorectal cancer, a finding that opens promising new research avenues for the development of approaches to prevent and treat the disease.

16 Aug 2013

Scientists uncover potential drug target for effective therapy against bacterial disease brucellosis

UC Davis scientists have uncovered a potential drug target for the development of an effective therapy against the debilitating, chronic form of the bacterial disease brucellosis, which primarily afflicts people in Mediterranean and Middle Eastern countries.

16 Aug 2013

Investigators link acute viral infections to development of COPD

Investigators at Washington University School of Medicine in St. Louis have described another link in the chain of events that connect acute viral infections to the development of chronic obstructive pulmonary disease (COPD).

16 Aug 2013

African-American women who experience racism have greater likelihood of adult-onset asthma

According to a new study from the Slone Epidemiology Center (SEC) at Boston University, African-American women who reported more frequent experiences of racism had a greater likelihood of adult-onset asthma compared to women who reported less frequent experiences.

16 Aug 2013

Preventive antibiotics for HIV patients lower risk of TB or death

As part of the largest international research effort ever made to combat tuberculosis, a team of Johns Hopkins and Brazilian experts has found that preventive antibiotic therapy for people with HIV lowers this group's chances of developing TB or dying.

16 Aug 2013

Animal model of HIV sexual transmission

Infection by human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS), a debilitating disorder in which progressive weakening of the immune system makes affected individuals more susceptible to potentially life-threatening infections and chronic diseases. Despite advances in the treatment and management of AIDS, there is no cure, and HIV infection remains a major global health problem.

16 Aug 2013

New treatment technique uses nanoparticles to attack cancer

Researchers at the University of Georgia are developing a new treatment technique that uses nanoparticles to reprogram immune cells so they are able to recognize and attack cancer. The findings were published recently in the early online edition of ACS Nano.

16 Aug 2013

Training to caregivers can enhance lives of children born with HIV

Children born with HIV can live longer and richer lives if their caregivers receive training in ways to enhance the children's development, according to research led by Michigan State University.

16 Aug 2013

Exo70 protein responsible for plasma membrane reshaping and cell movement

Both basic scientists and clinicians have an interest in how the cells of our body move. Cells must be mobile in order for organisms to grow, to heal, to transmit information internally, to mount immune responses and to conduct a host of other activities necessary for survival.

14 Aug 2013

A*STAR's SIgN discovers new strategy to develop universal dengue vaccine

A new strategy that cripples the ability of the dengue virus to escape the host immune system has been discovered by A*STAR's Singapore Immunology Network. This breakthrough strategy opens a door of hope to what may become the world's first universal dengue vaccine candidate that can give full protection from all four serotypes of the dreadful virus.

14 Aug 2013

Poly(lactic-co-glycolic acid) conduits suitable for sciatic nerve injury repair

The conventional method for repair of peripheral nerve injury is autogenous nerve grafting, but sources of autogenous nerve are limited. Furthermore, neurological deficits in the donor site and painful neuroma can occur following surgery.

14 Aug 2013

Immune System News and Research

New type of cancer immunotherapy harnesses body's immune system to attack tumors

Powerful mechanism helps viruses evade body's immune response

Arrays of nanoscale sensors detect flaws in drugs and help improve production

Dermatology researcher receives NIH grant to investigate role of nervous system in psoriasis

Pre-doctoral students receive International Student Research Fellowships from HHMI

Study shows lymph node location influences maturation process of cells they contain

GHI research aims to target breast cancer stem-like cells using immunotherapy

Phase II trial to investigate vaccine therapy combined with Avastin for patients with recurrent GBM

Research: MRSA in humans originated in cattle at least 40 years ago

Researchers discover how common oral bacterium can contribute to colorectal cancer

Scientists uncover potential drug target for effective therapy against bacterial disease brucellosis

Investigators link acute viral infections to development of COPD

African-American women who experience racism have greater likelihood of adult-onset asthma

Preventive antibiotics for HIV patients lower risk of TB or death

Animal model of HIV sexual transmission

New treatment technique uses nanoparticles to attack cancer

Training to caregivers can enhance lives of children born with HIV

Exo70 protein responsible for plasma membrane reshaping and cell movement

A*STAR's SIgN discovers new strategy to develop universal dengue vaccine

Poly(lactic-co-glycolic acid) conduits suitable for sciatic nerve injury repair

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