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Study reveals sharp increase in emergency department visits due to water beads

Researchers from the Center for Injury Research and Policy and Central Ohio Poison Center at Nationwide Children's Hospital have found more than an estimated 8,000 visits to U.S. emergency departments (EDs) associated with water beads from 2007 through 2022, and the number of these visits increased rapidly by more than 130% from 2021 to 2022.

13 Aug 2024

Researchers develop new method to study critical type of protein modification process

Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability.

12 Aug 2024

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

Scientists from St. Jude Children's Research Hospital, Seattle Children's and the Children's Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer.

12 Aug 2024

New breast cell atlas sheds light on genetic ancestry's role in cancer development

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date.

12 Aug 2024

Researchers identify key genetic players in dopamine signaling using transparent worms With The Help Of A Tin...

Dopamine, a powerful brain chemical and neurotransmitter, is a key regulator of many important functions such as attention, experiencing pleasure and reward, and coordinating movement.

12 Aug 2024

Prenatal BPA exposure tied to autism risk in boys

Study reveals that prenatal exposure to BPA disrupts aromatase activity in male brains, potentially leading to autism-like symptoms. Treatment with 10-HDA shows promise in reversing these effects.

11 Aug 2024

DeepPBS: A geometric AI model for accurate prediction of protein-DNA binding specificity

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments.

9 Aug 2024

Breakthrough study uncovers TIP60’s role in DNA access and disease mechanisms

To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions.

9 Aug 2024

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene's code affect health.

9 Aug 2024

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological processes in cells.

8 Aug 2024

Breakthrough study highlights ATM activation by DNA single-strand breaks

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

7 Aug 2024

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

7 Aug 2024

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

A new drug for treatment of a type of brain cancer, called IDH-mutant low-grade glioma, was approved Aug. 6 by the U.S. Food and Drug Administration (FDA).

7 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

Study reveals distinct genetic risk factors for influenza and COVID-19

A recent study in Nature Genetics reports that genetic risk factors for influenza and COVID-19 are distinct, highlighting their unique genetic architectures.

6 Aug 2024

Breakthrough therapy enhances longevity and vitality in aging mice

Everyone wants to live to a ripe old age, but no one wants to be decrepit. Now, University of Connecticut researchers have demonstrated a treatment that could lengthen life - and vigor - up to the very end.

6 Aug 2024

AI reveals genetic links in aging, chronic diseases, and lifestyle factors across nine organ systems

Research uncovers how genetic factors influence the biological age of different organ systems, revealing their connections to lifestyle, chronic diseases, and potential therapeutic interventions.

5 Aug 2024

Breakthrough study identifies mechanisms behind glucocorticoid resistance in pediatric B-ALL

Josep Carreras Leukaemia Research Institute B-ALL is the most common paediatric cancer and, over the years and thanks to a very effective treatment based on glucocorticoids, its 5-year survival rates have reached 85% and beyond.

5 Aug 2024

Unraveling complex genetic and environmental landscape of schizophrenia

Patrick Sullivan, MD, FRANZCP, the Yeargan Distinguished Professor of Psychiatry and Genetics at the UNC School of Medicine, and researchers at the Karolinska Institutet in Stockholm, Sweden, have developed a comprehensive outline of the genetics of schizophrenia.

2 Aug 2024

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Emory researcher David Weiss has spent years studying a baffling phenomenon called heteroresistance, in which a tiny fraction of bacteria remain resistant to antibiotics, while the remainder succumb.

2 Aug 2024

Genome News and Research

Study reveals sharp increase in emergency department visits due to water beads

Researchers develop new method to study critical type of protein modification process

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

New breast cell atlas sheds light on genetic ancestry's role in cancer development

Researchers identify key genetic players in dopamine signaling using transparent worms With The Help Of A Tin...

Prenatal BPA exposure tied to autism risk in boys

DeepPBS: A geometric AI model for accurate prediction of protein-DNA binding specificity

Breakthrough study uncovers TIP60’s role in DNA access and disease mechanisms

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

Breakthrough study highlights ATM activation by DNA single-strand breaks

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

Study advances understanding of complex neurological disorder

Study reveals distinct genetic risk factors for influenza and COVID-19

Breakthrough therapy enhances longevity and vitality in aging mice

AI reveals genetic links in aging, chronic diseases, and lifestyle factors across nine organ systems

Breakthrough study identifies mechanisms behind glucocorticoid resistance in pediatric B-ALL

Unraveling complex genetic and environmental landscape of schizophrenia

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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