Immune System News and Research

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UVA findings hold promise for developing targeted treatments for Long COVID lung complications

Groundbreaking research from the University of Virginia School of Medicine has revealed crucial new insights into the immune systems of COVID-19 survivors, particularly those struggling with persistent breathing issues.

5 May 2025

Gene-edited immune cells show promise against advanced GI cancers

Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers.

3 May 2025

New three-part antivenom cocktail protects against the world’s deadliest snakes

Scientists developed a groundbreaking antivenom cocktail using antibodies from a hyperimmune human donor and a small-molecule inhibitor that protected mice from deadly bites of 19 diverse snakes. This approach could lead to a universal antivenom for the world’s most dangerous snakes, overcoming the limitations of current species-specific treatments.

2 May 2025

New insights into facial bacteria may improve acne treatment strategies

The composition of bacterial populations living on our faces plays a significant role in the development of acne and other skin conditions such as eczema.

2 May 2025

ZIP4 protein identified as driver of glioblastoma aggression

In a study published Wednesday in the Proceedings of the National Academy of Sciences (PNAS), University of Oklahoma researchers detail their discoveries about why the brain tumor glioblastoma is so aggressive.

2 May 2025

Gut immune cells linked to worsening rheumatoid arthritis

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

2 May 2025

New antibody design enhances immune system's ability to fight cancer

Cancer scientists say they have engineered a new type of super-strong antibody which could be used to boost the immune systems of patients fighting the disease.

1 May 2025

Study links pregnancy specific genes to poorer lung cancer outcomes in women

Lung cancer can co-opt genes that normally help a fetus develop and evade the mother's immune system. And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men and women, female patients had poorer outcomes, a Memorial Sloan Kettering Cancer Center (MSK) research team has found.

29 Apr 2025

HonorHealth Research Institute treats first patient in global trial targeting aggressive melanoma

HonorHealth Research Institute recently treated the first patient in a 50-site international clinical trial that will test a new type of therapy aimed at difficult-to-treat melanoma, an aggressive type of skin cancer.

29 Apr 2025

$Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma$

Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma

Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukaemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 protein (HSP-CAR30), which has shown high efficacy in patients with refractory CD30+ lymphoma.

29 Apr 2025

Influenza virus hijacks human gene regulator to evade immune system

The influenza virus manipulates the body's gene regulation system to accelerate its own spread, according to researchers at the University of Gothenburg.

28 Apr 2025

UQ begins first human trial of immunotherapy for Type 1 diabetes

Researchers at The University of Queensland have dosed 5 participants in the first clinical trial of a potentially revolutionary immunotherapy drug to treat Type 1 diabetes.

28 Apr 2025

Immune evasion found in early stages of HPV-related anogenital lesions

A new research paper was published in Oncotarget, Volume 16, on April 24, 2025, titled "PD-L1 and FOXP3 expression in high-grade squamous intraepithelial lesions of the anogenital region."

28 Apr 2025

High cannabis use associated with increased colon cancer mortality

Researchers at the University of California San Diego School of Medicine have found that individuals with colon cancer and a documented history of high cannabis use were more than 20 times more likely to die within five years of diagnosis compared to those without such a history.

28 Apr 2025

Adaptive NK cells can effectively target ovarian cancer, study shows

Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumors and effectively attack them.

28 Apr 2025

Dana-Farber experts present innovative cancer studies at the 2025 AACR Annual Meeting

Numerous studies conducted by researchers at Dana-Farber Cancer Institute report progress for cancers including head and neck cancer, metastatic breast cancer and lung cancer.

27 Apr 2025

Distinct subtypes of senescent skin cells identified

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.

26 Apr 2025