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Complete structure of Insulin receptor discovered - may assist in drug development for diabetes

Insulin is one of the most commonly used therapeutic agents used in diabetes. While the structure of this complex protein has been studied in detail there were parts of the receptor for insulin that were not clearly defined till now. This receptor is a protein that exists on the surfaces of cells and binds to the insulin molecule. These receptors are responsible for the action of insulin on the cells.

24 Mar 2010

Protein deficiency in Down syndrome patients could contribute to cognitive impairment and congenital heart defects

Conventional wisdom among scientists for years has suggested that because individuals with Down syndrome have an extra chromosome, the disorder most likely results from the presence of too many genes or proteins contained in that additional structure.

24 Mar 2010

Renowned leaders to discuss latest findings in early-stage drug development for cancer

When people think of cancer treatment, chemotherapy infusions, injections and pills often come to mind. These treatments result from extensive research and testing in drug development. But how does the process begin?

24 Mar 2010

Inhibitex announces net loss of $4.7M for fourth-quarter 2009

Inhibitex, Inc. today announced its financial results for the fourth quarter and year ended December 31, 2009 and provided an update on various corporate developments.

23 Mar 2010

Study: Replacing dietary saturated fats with polyunsaturated fatty acids reduces coronary heart disease

A study in this week's PLoS Medicine shows that the replacement of dietary saturated fatty acids with polyunsaturated fatty acids reduces coronary heart disease events, bringing much needed scientific evidence to an issue debated by experts and clinical guidelines.

23 Mar 2010

Labeling calories on menus mandatory – unhealthy eating discouraged further

With the newly passed healthcare bill calorie counts at fast food and chain restaurants become mandatory. More than 200,000 fast food and other chain restaurants will have to include calorie counts on menus, menu boards, buffets, vending machines, alcoholic drink menus and even drive-throughs.

23 Mar 2010

Treating RNA segment in wounds may increase protein levels for growth of skin cells

Scientists have determined that chronic wounds might have trouble healing because of the actions of a tiny piece of a molecular structure in cells known as RNA.

23 Mar 2010

Blocking Bak inhibitors can be promising strategy in limiting resistance of cancer to TRAIL

The TRAIL ligand is a promising anticancer agent that preferentially kills tumor cells without apparent damage to healthy cells. Many cancers exhibit resistance to TRAIL, however, thus limiting its therapeutic potential.

23 Mar 2010

Walnuts affect genes related to prostate tumor growth: Study

Walnut consumption slows the growth of prostate cancer in mice and has beneficial effects on multiple genes related to the control of tumor growth and metabolism, UC Davis and the U.S. Department of Agriculture Western Regional Research Center in Albany, Calif. have found.

23 Mar 2010

Ultraviolet portion of sunlight may play bigger role in controlling MS: Study

For more than 30 years, scientists have known that multiple sclerosis (MS) is much more common in higher latitudes than in the tropics. Because sunlight is more abundant near the equator, many researchers have wondered if the high levels of vitamin D engendered by sunlight could explain this unusual pattern of prevalence.

23 Mar 2010

GUMC scientists awarded five-year $7.5M grant to perfect treatment of breast cancer

Scientists at the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center were awarded a five-year $7.5 million grant to tease apart - in the most comprehensive way ever devised -the role of a single protein receptor in breast cells in cancer development and treatment.

22 Mar 2010

PharmAthene to provide update on contract modification suspension

PharmAthene, Inc., a biodefense company developing medical countermeasures against biological and chemical threats, announced today that in addition to its year end results, it will provide an update on the contract modification suspension it received on Friday, March 19, 2010.

22 Mar 2010

CRT, Cephalon to collaborate on development of small molecule inhibitors against cancer

Cancer Research Technology has announced an exclusive agreement with Cephalon, Inc., an international biotechnology company, to collaborate on the development of small molecule inhibitors. These molecules will target specific members of the 'protein kinase C' superfamily of cell signalling proteins - which have been shown to be associated with the development of cancer.

22 Mar 2010

Microglia contribute to loss of neurons linked with Alzheimer's disease

Microglia are the cells responsible for immune surveillance in the brain, and they initiate protective inflammatory reactions in response to tissue damage and infection. An international team under the leadership of LMU neuroscientist Professor Jochen Herms has now shown that these cells may actually make a significant contribution to the loss of neurons associated with Alzheimer's disease.

22 Mar 2010

Calando Pharmaceuticals demonstrates first targeted siRNA-containing nanoparticle delivery to tumors

Arrowhead Research Corporation today announced that the clinical trial being conducted by majority-owned subsidiary, Calando Pharmaceuticals, Inc., has demonstrated systemic delivery of siRNA and the successful “silencing” of a widely recognized cancer gene via RNA interference (RNAi) in humans.

22 Mar 2010

Gene implicated in JSRDs: UCD research team publishes new information

Researchers in University College Dublin (UCD) led by Conway Fellow, Dr Oliver Blacque have revealed new information about a gene implicated in Joubert syndrome and related cerebellar disorders (JSRDs) that are characterised by blindness, bone abnormalities, cystic kidneys, developmental delay and loss of muscle tone and control. The findings from this research, which is funded by Science Foundation Ireland, have been published today in a leading science journal, Journal of Cell Biology.

22 Mar 2010

Lab on a Chip for research on oxygen impact on brain cells

A mini-laboratory that makes it possible, among other things, to study how brain cells in stroke patients are affected by lack of oxygen is being developed by a research team at Luleå University of Technology in Sweden. Lab on a Chip is what the scientists are calling their mini-lab, which is expected to facilitate studies of all sorts of biological cells and how they are affected by different medicines, chemical substances, etc.

22 Mar 2010

'Doublesex' gene also sculpts brain and nervous system architecture leading to sex-specific behaviours

The brains of males and females, and how they use them, may be far more different then previously thought, at least in the fruit fly Drosophila melanogaster, according to research funded by the Wellcome Trust.

22 Mar 2010

Shastha Foods, South Asian Heart Center form food partnership

Santa Clara-based Shastha Foods and the South Asian Heart Center at El Camino Hospital have announced they have collaborated to create newly formulated versions of the company’s popular fresh, stone ground “dosa” batter using the Center’s nutritional guidelines for healthy heart-savvy ingredients.

22 Mar 2010

Nanotechnology weapons for cancer

US Researchers have come up with new nanoparticle robots that are essentially a tiny army that can travel in the blood till they reach the cancers and then tweak some important cancer causing genes that can cure the cancer.

22 Mar 2010

G Protein News and Research

Complete structure of Insulin receptor discovered - may assist in drug development for diabetes

Protein deficiency in Down syndrome patients could contribute to cognitive impairment and congenital heart defects

Renowned leaders to discuss latest findings in early-stage drug development for cancer

Inhibitex announces net loss of $4.7M for fourth-quarter 2009

Study: Replacing dietary saturated fats with polyunsaturated fatty acids reduces coronary heart disease

Labeling calories on menus mandatory – unhealthy eating discouraged further

Treating RNA segment in wounds may increase protein levels for growth of skin cells

Blocking Bak inhibitors can be promising strategy in limiting resistance of cancer to TRAIL

Walnuts affect genes related to prostate tumor growth: Study

Ultraviolet portion of sunlight may play bigger role in controlling MS: Study

GUMC scientists awarded five-year $7.5M grant to perfect treatment of breast cancer

PharmAthene to provide update on contract modification suspension

CRT, Cephalon to collaborate on development of small molecule inhibitors against cancer

Microglia contribute to loss of neurons linked with Alzheimer's disease

Calando Pharmaceuticals demonstrates first targeted siRNA-containing nanoparticle delivery to tumors

Gene implicated in JSRDs: UCD research team publishes new information

Lab on a Chip for research on oxygen impact on brain cells

'Doublesex' gene also sculpts brain and nervous system architecture leading to sex-specific behaviours

Shastha Foods, South Asian Heart Center form food partnership

Nanotechnology weapons for cancer

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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