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Chronic inflammation combines with DNA methylation to promote development of colorectal cancer

Chronic inflammation combines with DNA methylation, a process that shuts down cancer-fighting genes, to promote development of colorectal cancer, scientists at The University of Texas MD Anderson Cancer Center report today in the advance online publication of the journal Nature Medicine.

23 Jan 2012

Researchers create first 3D structure of key cancer protein

Cancer Research UK scientists have created the first 3D structure of a key protein that protects against the development of cancer, according to research published in Nature Structural & Molecular Biology today.

22 Jan 2012

A*STAR, GE Global Research join forces in integrated advanced medical imaging technologies

GE Global Research, the central technology development arm for GE Healthcare and all of GE's businesses, has signed a Memorandum of Understanding (MOU) with Singapore's Agency of Science, Technology and Research (A*STAR). This agreement will focus on advancing current medical imaging technologies and diagnostics to enable more accurate, earlier and faster clinical diagnoses of cancer and other diseases. The partnership between A*STAR and GE Global Research brings together two world-class research institutions, integrating their deep domain expertise in biomedical, science, and engineering capabilities to support this effort.

22 Jan 2012

Genes may predict maintenance of intelligence over lifetime: Study

A Scottish study that began 80 years ago has shown that genes may play a role in maintaining intelligence till old age. The study participants joined when they were 11 years old. Researchers have long been interested in understanding how cognition changes with age, and why these changes are more rapid in some people than in others. But, in the past, studies of age-related intelligence changes were often performed when the subjects were already elderly.

22 Jan 2012

SSRI use raises risk of fall among elderly with dementia: Study

A new study reveals that nursing home residents with dementia who use selective serotonin reuptake inhibitors (SSRIs) have an increased risk of having a fall that causes injury compared with those who do not use SSRIs. Additionally those using average doses have 3 times the risk compared with nonusers, the authors, led by Carolyn S. Sterke, from Erasmus University Medical Center, Rotterdam, the Netherlands, report. Authors write, “Even at low doses, SSRIs are associated with increased risk of an injurious fall in nursing home residents with dementia.”

22 Jan 2012

Artificial testes being developed to help infertile men produce sperm

Californian researchers are trying to create an artificial testicle that will produce human sperm. Dr. Paul Turek, director of the Turek Clinic in San Francisco, which specializes in male infertility, said the goal is not to create a testicular implant for men, but a “sperm-making biological machine” that will help scientists learn more about just what causes male infertility. “We’re trying to recreate the process of sperm production in a three-dimensional system,” Turek said. “Simple laboratory conditions can’t get it done in humans. Our concept is to actually recreate the testicle itself.”

22 Jan 2012

Sex declared safe for heart patients

A doctors’ group on Thursday suggested that sex may be safe for most heart patients. The American Heart Association added that having sex only slightly raises the chance for a heart attack. And that’s true for people with and without heart disease. Despite the higher risk for a heart patient to have a second attack, there’s no evidence that they have more sex-related heart attacks than people without cardiac disease. The updated advice was released online Thursday in the heart association journal, Circulation.

22 Jan 2012

Number of unsafe abortions soars worldwide: Report

A new worldwide analysis by the Guttmacher Institute and the World Health Organization shows that unsafe abortions are on the rise across the world. After a period of significant decline in the global abortion rate as a whole, researchers found that those numbers had begun to plateau. The report was published in the Lancet.

22 Jan 2012

President to push Congress to revisit ambitious effort to cut the deficit

And, House and Senate negotiators will hold a rare public meeting Tuesday about the payroll tax cut and the Medicare reimbursement rate for physicians.

21 Jan 2012

Proposed new definition may affect individuals who qualify for autism diagnosis

Getting an autism diagnosis could be more difficult in 2013 when a revised diagnostic definition goes into effect. The proposed changes may affect the proportion of individuals who qualify for a diagnosis of autism spectrum disorder, according to preliminary data presented by Yale School of Medicine researchers at a meeting of the Icelandic Medical Association.

21 Jan 2012

Kodak's Chapter 11 filing: Retiree benefit costs a big part of the problem

Here's one way of understanding Eastman Kodak Co.'s problems: The company has twice as many retirees drawing benefits in the U.S. as it has active employees world-wide. … Kodak has been whittling away at those benefits for years and says it wants to accelerate the process in Chapter 11 proceedings. … The company said in a filing Thursday that it is liable for $1.3 billion in U.S. retirement benefits such as health care.

21 Jan 2012

IMB announces new International Summer School in the Life Sciences

The Institute of Molecular Biology (IMB) has announced a new International Summer School (ISS) in the Life Sciences. The ISS will take place from 16th July to 24th August 2012 and will provide outstanding and enthusiastic undergraduate, Master's and PhD students the opportunity to undertake exciting research projects.

21 Jan 2012

UNAIDS officials say progress being made against HIV/AIDS in Africa, Asia

Speaking at a media briefing in Geneva on Thursday, Sheila Tlou, UNAIDS director of the regional support team for Eastern and Southern Africa, said the region is making progress in scaling up access to prevention and treatment services, including behavior change and prevention of mother-to-child transmission (PMTCT) programs, the U.N. News Centre reports.

21 Jan 2012

First genome-wide study of high-altitude adaptations in Ethiopians

Over many generations, people living in the high-altitude regions of the Andes or on the Tibetan Plateau have adapted to life in low-oxygen conditions. Living with such a distinct and powerful selective pressure has made these populations a textbook example of evolution in action, but exactly how their genes convey a survival advantage remains an open question. Now, a University of Pennsylvania team has made new inroads to answering this question with the first genome-wide study of high-altitude adaptations within the third major population to possess them: the Amhara people of the Ethiopian Highlands.

21 Jan 2012

Health law, abortion among hot topics in S.C. Republican primary debate

The GOP presidential hopefuls clashed on a range of issues related to the health law, its individual mandate and efforts to repeal it. Candidates' positions on abortion were also flashpoints.

21 Jan 2012

Younger women with breast cancer experience a decrease in health-related QOL

Younger women with breast cancer experience a decrease in their health-related quality of life (QOL), associated with increased psychological distress, weight gain, a decline in their physical activity, infertility and early onset menopause, according to a study published January 20 in the Journal of the National Cancer Institute.

21 Jan 2012

Federal judge renews her order blocking Calif. cuts to in-home care

A federal judge will continue blocking millions of dollars in cuts to in-home care for the elderly and the disabled, parties to a lawsuit over the services said Thursday. U.S. District Judge Claudia Wilken had temporarily halted the cuts in December. The $100 million in reductions to home aid, built into the state budget in case revenue did not match projections, were to have kicked in this month.

21 Jan 2012

Keeping global health relevant as part of sustainable development agenda

"In 2012 there will be a major strategic shift in global health, away from development and towards sustainability," a Lancet editorial states.

21 Jan 2012

New tool to improve ease of oral fluid collection

Researchers are constantly finding new ways to figure out what makes us human beings tick, and one of the newer methods makes you want to spit—literally. Saliva is full of analytes and biomarkers that create a biological journal of exposure to chemicals and disease, and genetic variability. However, the collection of oral fluid has always proved cumbersome, with researchers depending on swabs or collection cups.

21 Jan 2012

India's Ministry of Health dismisses claims of 'totally drug-resistant' TB

In a January 17 statement, India's Ministry of Health and Family Welfare "dismissed reports that a form of incurable tuberculosis [TB] has arrived in the country," saying "that a team of doctors sent by the ministry found that seven of the patients are responding to treatment" and the cases would be classified and managed as extremely drug-resistant TB (XDR-TB), Nature News Blog reports.

21 Jan 2012