Immune System News and Research

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Solid formulations of the recombinant anthrax vaccine: an interview with Dr Mark Carnegie-Brown, CEO, Glide Pharma

Anthrax vaccines have a prominent place in the history of medicine. This goes back to, Pasteur, who while everybody associates with the milk treatment process, also worked on rabies and Anthrax vaccines in cattle.

6 Jun 2013

Medicago reports positive interim results from preclinical trial for H7 VLP vaccine candidate

Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today reported positive interim results from a preclinical trial for an H7N9 Avian Influenza VLP vaccine candidate ("H7 vaccine").

6 Jun 2013

Scientists discover protective role of retinoic acid against intestinal inflammation

Scientists at Trinity College Dublin have made novel discoveries around the protective influence of Vitamin A against the damaging immune responses that lead to inflammatory bowel disease.

5 Jun 2013

Cells with amplified HER2 gene need to be considered carefully, study says

Biocept, Inc., a privately-held, CLIA certified laboratory testing company focused on detection and analysis of circulating tumor cells and circulating tumor DNA in cancer patients, reported the publication in the journal Cancer Medicine of a paper entitled "Discordance in HER2 gene amplification in circulating and disseminated tumor cells in patients with operable breast cancer" on research performed with collaborators from the University of Texas MD Anderson Cancer Center.

5 Jun 2013

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

In a pair of distinct but complementary papers, researchers at the University of California, San Diego School of Medicine and colleagues illuminate the functional importance of a relatively new class of RNA molecules.

5 Jun 2013

New approach in treating multiple sclerosis

In his article, "Pathoetiology of multiple sclerosis: are we barking up the wrong tree?", Peter K. Stys of the Hotchkiss Brain Institute, University of Calgary, argues that while the majority of the medical research community currently approaches MS as an autoimmune disease (much like Lupus and Rheumatoid Arthritis), for which the trigger is the immune system attacking a particular part of the nervous system, the features of the disease are equally well explained by approaching MS as a neurodegenerative disease (such as Parkinson's and Alzheimer's), which is followed by an immune reaction to damage.

5 Jun 2013

Six top scientists studying psoriasis receive NPF research grants to discover new treatments for chronic diseases

Six of the top scientists studying psoriasis-the most common autoimmune disease in the country, affecting 7.5 million Americans-and psoriatic arthritis, an inflammatory joint and tendon disease affecting up to 30 percent of people with psoriasis, received National Psoriasis Foundation (NPF) research grants totaling $450,000 for projects that aim to discover new treatments and a cure for these chronic diseases.

5 Jun 2013

Patients who receive antibiotics while in hospital may benefit from probiotics, say researchers

Patients in hospital who are on antibiotics may benefit from taking probiotics, according to researchers at St. Michael-s Hospital.

5 Jun 2013

Researchers discover way to stop atherosclerosis caused by diabetes

Researchers at Lund University in Sweden have discovered how to stop the destructive process that leads to cardiovascular disease in diabetic laboratory animals.

5 Jun 2013

EU funds d-LIVER project to help people suffering from liver disease

The EU has provided funding for the d-LIVER project, in which researchers from several countries will work on a number of measures to help people suffering from liver disease.

5 Jun 2013

Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

The same mechanism that lets the immune system mount a massive attack against invading bacteria contributes to the destruction of brain cells as part of Parkinson's disease, according to a study published online today in the Journal of Neuroscience.

5 Jun 2013

Researchers demonstrate how modified citrus pectin works against cancer

A new review by researchers at the University of Maryland School of Medicine highlights a large body of published research demonstrating how modified citrus pectin, works against cancer.

4 Jun 2013

New technique selectively represses unwanted immune reactions without disabling immune system

The human immune system is remarkably efficient, but sometimes its attack is misdirected, leading to allergies, autoimmune diseases and rejection of transplant organs and therapeutic drugs. Current immune suppressants have major drawbacks, but a team from The Scripps Research Institute (TSRI) has demonstrated a new technique that may lead to a better way to selectively repress unwanted immune reactions without disabling the immune system as a whole.

4 Jun 2013

Study examines link between IL-17F and treatment response to interferon beta-1b in multiple sclerosis patients

A study by Hans-Peter Hartung, M.D., of Heinrich-Heine-Universität, Düsseldoft, Germany, and colleagues examines the association between IL-17F and treatment response to interferon beta-1b among patients with relapsing-remitting multiple sclerosis.

4 Jun 2013

Cancer immunotherapy shows promise in treating patients with metastatic tumors

Cancer immunotherapy is showing promise in treating patients with a variety of advanced, metastatic tumors, as evidenced by two newly unveiled studies from Yale Cancer Center.

4 Jun 2013

Weather may influence transmission of West Nile, chikungunya, and other viral disease

Urban epidemics resulting from viral diseases, such as West Nile fever and chikungunya fever, are transmitted by infected mosquitoes.

4 Jun 2013

Study supports role of skin sodium in blood pressure regulation

It's time to expand the models for blood pressure regulation, according to clinical pharmacologist Jens Titze, M.D. Titze and his colleagues have identified a new cast of cells and molecules that function in the skin to control sodium balance and blood pressure.

4 Jun 2013

BACH2 gene may play a central role in the development of allergic and autoimmune diseases

Scientists at the National Institutes of Health, and their colleagues, have discovered that a gene called BACH2 may play a central role in the development of diverse allergic and autoimmune diseases, such as multiple sclerosis, asthma, Crohn's disease, celiac disease, and type-1 diabetes.

4 Jun 2013

Data from Nivolumab phase I study in patients with kidney cancer to be presented at ASCO 2013

Researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center will present a poster on a phase I clinical trial of Nivolumab, a PD-1 receptor blocking antibody, being used in combination with other drugs in patients with metastatic renal cell carcinoma at the ASCO Annual Meeting on June 3, 2013.

4 Jun 2013

Mathematical modeling proved critical in understanding latent stage of infections

Recurrent infection is a common feature of persistent viral diseases. It includes episodes of high viral production interspersed by periods of relative quiescence. These quiescent or silent stages are hard to study with experimental models. Mathematical analysis can help fill in the gaps.

3 Jun 2013

Immune System News and Research

Solid formulations of the recombinant anthrax vaccine: an interview with Dr Mark Carnegie-Brown, CEO, Glide Pharma

Medicago reports positive interim results from preclinical trial for H7 VLP vaccine candidate

Scientists discover protective role of retinoic acid against intestinal inflammation

Cells with amplified HER2 gene need to be considered carefully, study says

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

New approach in treating multiple sclerosis

Six top scientists studying psoriasis receive NPF research grants to discover new treatments for chronic diseases

Patients who receive antibiotics while in hospital may benefit from probiotics, say researchers

Researchers discover way to stop atherosclerosis caused by diabetes

EU funds d-LIVER project to help people suffering from liver disease

Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

Researchers demonstrate how modified citrus pectin works against cancer

New technique selectively represses unwanted immune reactions without disabling immune system

Study examines link between IL-17F and treatment response to interferon beta-1b in multiple sclerosis patients

Cancer immunotherapy shows promise in treating patients with metastatic tumors

Weather may influence transmission of West Nile, chikungunya, and other viral disease

Study supports role of skin sodium in blood pressure regulation

BACH2 gene may play a central role in the development of allergic and autoimmune diseases

Data from Nivolumab phase I study in patients with kidney cancer to be presented at ASCO 2013

Mathematical modeling proved critical in understanding latent stage of infections

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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