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Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Gaucher disease, a rare enzyme deficiency disorder, is one of many conditions with few approved treatment options for patients. In a study published online today in Blood, the journal of the American Society of Hematology, researchers present positive results of a Phase II clinical trial of eliglustat tartrate, an oral therapy in development to treat Gaucher disease.

4 May 2010

Broccoli component sulforaphane targets and kills breast cancer stem cells

A compound derived from broccoli could help prevent or treat breast cancer by targeting cancer stem cells -- the small number of cells that fuel a tumor's growth -- according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

4 May 2010

Statins may improve longevity of hip replacement surgery

The use of statins - drugs commonly prescribed to help lower cholesterol levels - may play an important role in decreasing complications among patients undergoing total hip replacement (THR), according to a study published in the May 2010 issue of the Journal of Bone and Joint Surgery (JBJS).

4 May 2010

Researchers convert established human iPS cells, ES cells to base state of greater pluripotency

Whitehead Institute researchers have converted established human induced pluripotent stem cells and human embryonic stem cells to a base state of greater pluripotency.

4 May 2010

One-half of physicians do not recommend bariatric surgery for adolescents

Severely obese adolescents may desire or potentially benefit from bariatric surgery. However, half of primary care physicians say they would not recommend the procedure to a patient under the age of 18, according to research published in Obesity Surgery

4 May 2010

NIH awards Hutchinson Center $10.24M for research of breast cancer disparities in Hispanic women

The National Institutes of Health has awarded $10.24 million to Fred Hutchinson Cancer Research Center to lead a five-year study that aims to understand and prevent breast cancer disparities in Hispanic women.

4 May 2010

TB Alliance, AstraZeneca sign research collaboration agreement to develop drugs against tuberculosis

The Global Alliance for TB Drug Development and AstraZeneca announced today at the 2010 BIO International Convention that they have entered into a research collaboration agreement to accelerate the discovery, development and clinical use of drugs against tuberculosis, including drug resistant strains of the disease.

4 May 2010

Researchers receive $250,000 to study inventive cell-transfer therapy to treat cortical dysplasia

University of Florida researchers will receive $250,000 to study an inventive cell-transfer therapy to treat cortical dysplasia, a condition where the brain develops abnormally before birth, causing severe epilepsy in children and adults.

4 May 2010

Pregnant Arab women have high prevalence of vitamin D deficiency: Study

Pregnant Arab women have an "extraordinarily high prevalence" of vitamin D deficiency - a potential health issue for them and their babies, according to a new Cincinnati Children's Hospital Medical Center study.

4 May 2010

Array BioPharma reports 18.4M revenue for third-quarter fiscal 2010

Array BioPharma Inc. today reported financial results for the third quarter of fiscal 2010.

4 May 2010

NIH awards UIC $10M grant to study health disparities among underserved, minority women with breast cancer

A $9.6 million grant from the National Institutes of Health has been awarded to the University of Illinois at Chicago to study access to care and health disparities among underserved and minority women with breast cancer in Chicago.

4 May 2010

Growth hormone boosts sprinting capacity in athletes but may have serious side effects

Human Growth Hormone (hGH) has long been used among athletes and body builders for stronger and a more muscular bodies over the past four decades. However it is only now that Sydney-based researchers have published a study that shows that hGH offers no such benefits.

3 May 2010

Boost for biologics manufacturing in Australia

AusBiotech has welcomed the news that Australia’s first major contract manufacturing facility for biologic medicines has secured backing and is set to be built in Queensland by 2012.

3 May 2010

WHO, UNICEF issue guide, call for more research into medicines for children

Along with the release of a WHO-UNICEF guide on medicines for children, the U.N. agencies on Friday said the guide "exposed dangerous shortfalls" in medicines designed for children and called for more research into treating children, Reuters reports. "While effective medicines exist to fight disease and treat life-threatening conditions like malnutrition, formulations suitable for children are often difficult to source," Francisco Blanco, UNICEF's chief of medicines and nutrition, said, according to the news service.

3 May 2010

Landec announces acquisition of Lifecore Biomedical from Warburg Pincus Private Equity

Landec Corporation, a materials science company that develops and markets patented polymer products for food, agriculture, personal care and drug delivery applications, today announced that it has acquired Lifecore Biomedical, Inc. from Warburg Pincus Private Equity IX, LP. When acquired by Warburg Pincus in March 2008, Lifecore was comprised of two divisions, the Dental Division and the Hyaluronan Division. The Dental Division was merged into a Warburg Pincus portfolio company.

3 May 2010

Researchers identify genes associated with cleft lip and/or cleft palate

An international consortium of scientists, led by researchers at Johns Hopkins University has identified two genes that when altered are closely associated with cleft lip and/or cleft palate. Cleft lip and cleft palate are among the world's most common congenital malformations and occur in one in every 700 births. The finding is the result of the largest family-based, genome-wide study of cleft lip and/or cleft palate conducted to date. The results were published online by the journal Nature Genetics.

3 May 2010

FDA issues advisory on prostate cancer drugs

Gonadotropin-Releasing Hormone (GnRH) agonists, a class of medications primarily used to treat men with prostate cancer, have been associated with a small increased risk for diabetes, heart attack, stroke, and sudden death in men treated with one of the medications, according to a preliminary and ongoing analysis of several studies by the U.S. Food and Drug Administration.

3 May 2010

Congress and the VA deal with complications of veterans' health care

The Associated Press/The Washington Post: Pressure from Congress telling the Department of Veterans Affairs that it should make it easier for veterans to settle their disability claims is seeing some controversy. "The system is dysfunctional, an open invitation to fraud. And the VA has proposed changes that could make deception even easier."

3 May 2010

HTG, JWCI collaborate to develop new approaches for early stage primary cutaneous melanoma diagnosis

HTG, Inc., provider of the quantitative Nuclease Protection Assay (qNPA™), today announced it signed a collaboration agreement with the John Wayne Cancer Institute (JWCI) at Saint John's Health Center in Santa Monica, California. Under the terms of the agreement, HTG and JWCI (Department of Molecular Oncology, Dave S. B. Hoon, Ph.D., Director) will collaborate to generate a novel mRNA signature that can measure the gene expression differences in melanoma and benign nevi using HTG's qNPA technology in classical surgical pathology samples.

3 May 2010

Interim study results demonstrate anti-tumor activity of CytRx's INNO-206 in myeloma tumor cells

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced interim study results that showed its doxorubicin prodrug INNO-206 demonstrated statistically significant anti-tumor activity in human myeloma tumor cells growing in immune-deficient mice compared to a control group, while exhibiting significantly less toxicity than doxorubicin even though INNO-206 was administered at much higher doses.

3 May 2010

Research News and Research

Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Broccoli component sulforaphane targets and kills breast cancer stem cells

Statins may improve longevity of hip replacement surgery

Researchers convert established human iPS cells, ES cells to base state of greater pluripotency

One-half of physicians do not recommend bariatric surgery for adolescents

NIH awards Hutchinson Center $10.24M for research of breast cancer disparities in Hispanic women

TB Alliance, AstraZeneca sign research collaboration agreement to develop drugs against tuberculosis

Researchers receive $250,000 to study inventive cell-transfer therapy to treat cortical dysplasia

Pregnant Arab women have high prevalence of vitamin D deficiency: Study

Array BioPharma reports 18.4M revenue for third-quarter fiscal 2010

NIH awards UIC $10M grant to study health disparities among underserved, minority women with breast cancer

Growth hormone boosts sprinting capacity in athletes but may have serious side effects

Boost for biologics manufacturing in Australia

WHO, UNICEF issue guide, call for more research into medicines for children

Landec announces acquisition of Lifecore Biomedical from Warburg Pincus Private Equity

Researchers identify genes associated with cleft lip and/or cleft palate

FDA issues advisory on prostate cancer drugs

Congress and the VA deal with complications of veterans' health care

HTG, JWCI collaborate to develop new approaches for early stage primary cutaneous melanoma diagnosis

Interim study results demonstrate anti-tumor activity of CytRx's INNO-206 in myeloma tumor cells

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