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Researchers identify effective drug combinations for malignant brain tumor in mice

Usually, scientists study the molecular biology of cancer to find new treatments, but sometimes, it is the other way round: when trying to find new treatments, scientists find key information on cancer biology.

14 Jun 2019

Roswell Park physician leads effort to compile new multiple myeloma imaging guidelines

Just as newer drugs have significantly improved outcomes for patients with multiple myeloma in the past decade, newer imaging techniques are upgrading detection of the disease, leading to earlier treatment.

14 Jun 2019

Experimental antiviral drug cures mice infected with deadly tick-borne virus

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness.

14 Jun 2019

Opioids alone cannot be blamed for growing life expectancy inequality in the U.S.

A new University of Michigan study challenges a popularized view about what's causing the growing gap between the lifespans of more- and less-educated Americans- finding shortcomings in the widespread narrative that the United States is facing an epidemic of "despair."

14 Jun 2019

New small drug-targeting molecules may improve cancer treatment

Researchers from the University of Notre Dame have developed small drug-targeting molecules that may be hundreds to thousands of times more effective at delivering potent drugs to desired sites of disease, including cancer.

14 Jun 2019

First clinical test could enable personalized prognosis for triple-negative breast cancer patients

A personalized prognosis for patients diagnosed with triple-negative breast cancer was the goal of a new study by Katherine Varley, PhD, researcher at Huntsman Cancer Institute and assistant professor of oncological sciences at the University of Utah.

13 Jun 2019

Disease-modifying therapy for Alport syndrome still remains an unmet need

Alport syndrome is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure.

13 Jun 2019

Physical exercise can reduce liver fat, improve blood sugar control in obese individuals

Research conducted at the University of Campinas in São Paulo State, Brazil, shows that vigorous physical exercise such as strength and weight training can reduce accumulated liver fat and improve blood sugar control in obese and diabetic individuals in a short time span, even before significant weight loss occurs.

13 Jun 2019

New smartphone app helps anorexic patients to normalize their eating rate

Swedish scientists say that eating disorders should be considered just that - eating disorders, rather than mental disorders. The proof, they say, is in the eating.

13 Jun 2019

Engineers crack the code to quickly diagnose anti-malarial drug resistance

One of the keys to quickly diagnosing anti-malarial drug resistance -- potentially saving lives -- lies in testing whole blood instead of extracting DNA, eliminating processing steps that can take hours or days.

13 Jun 2019

New assay uses a drop of blood to detect patients' resistance to antimalarial drugs

Antimalarial drugs appear to follow a typical pattern, with early effectiveness eventually limited by the emergence of drug resistance.

13 Jun 2019

Heart failure drug could be effective in treating leukemia

Canadian researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. Those efforts have borne fruit, as demonstrated by their work published in the Journal of Experimental and Clinical Cancer Research.

13 Jun 2019

Researchers develop first blood-brain barrier chip using stem cells

Researchers at Ben-Gurion University of the Negev and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier, creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.

13 Jun 2019

More screening and new treatments needed for sickle cell disease

The promise of new treatments for sickle cell disease, a group of inherited red blood cell disorders, has never been so great, but it will only be realized if there is constant investment in health policies such as programs for screening newborns, especially in sub-Saharan Africa, where most cases occur.

13 Jun 2019

New approach could help in treating brain tumors, other rare cancers

Large randomized clinical trials can uncover biomarkers that indicate which cancer treatments are likely to work best for individual patients. But it's been challenging to find these biomarkers in rarer cancers where such robust data aren't available.

13 Jun 2019

New robust and efficient methods for the production of new peptide drugs

Many important natural products such as antibiotics, immunosuppressants, or anti-cancer drugs are produced by microorganisms.

13 Jun 2019

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

The results of a randomized controlled trial presented today at the Annual European Congress of Rheumatology demonstrate high levels of treatment success in approximately two thirds of patients despite tapered glucocorticoid discontinuation, while a small loss of disease control was observed at the total study population level.

13 Jun 2019

Drugs News and Research

Researchers identify effective drug combinations for malignant brain tumor in mice

Roswell Park physician leads effort to compile new multiple myeloma imaging guidelines

Experimental antiviral drug cures mice infected with deadly tick-borne virus

Opioids alone cannot be blamed for growing life expectancy inequality in the U.S.

New small drug-targeting molecules may improve cancer treatment

First clinical test could enable personalized prognosis for triple-negative breast cancer patients

Disease-modifying therapy for Alport syndrome still remains an unmet need

Physical exercise can reduce liver fat, improve blood sugar control in obese individuals

New smartphone app helps anorexic patients to normalize their eating rate

Engineers crack the code to quickly diagnose anti-malarial drug resistance

New assay uses a drop of blood to detect patients' resistance to antimalarial drugs

Heart failure drug could be effective in treating leukemia

Researchers develop first blood-brain barrier chip using stem cells

More screening and new treatments needed for sickle cell disease

New approach could help in treating brain tumors, other rare cancers

New robust and efficient methods for the production of new peptide drugs

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

Identifying colorectal cancer subtypes in patients could help provide better care

Weighing risks and benefits of antidepressant medication for older adults

Human liver cell protein aids development of malaria parasite, study finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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