Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Blood NfL levels correlate with severity of Alzheimer's disease pathology

Neuroscience researchers at Wayne State University published a review article that confirms the usefulness of neurofilament light (NfL) blood levels to predict the likelihood and rate of progression of neurodegeneration in Alzheimer's disease.

31 Aug 2023

A type of gut bacteria may protect against the development of obesity and type-2 diabetes

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a type of gut bacteria that might help improve insulin resistance, and thus protect against the development of obesity and type-2 diabetes.

31 Aug 2023

The Clinical Importance of Circulating Tumor DNA

Cancer remains a leading killer among medical causes of death worldwide.

31 Aug 2023

Parkinson's disease diagnosis could be made earlier with new blood test

Researchers have developed a blood test that detects Parkinson's disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens.

30 Aug 2023

Higher educational attainment may have a protective effect against Alzheimer's in people with genetic risk

A new study by researchers from Mass General Brigham further illustrates that when it comes to risk of Alzheimer's disease, even genetically determined forms of the disease, genetics is only one piece of the puzzle.

30 Aug 2023

Study detects significant levels of metals in the blood and urine among marijuana users

Research conducted at Columbia University Mailman School of Public Health detected significant levels of metals in the blood and urine among marijuana users, concluding that marijuana may be an important and under-recognized source of lead and cadmium exposure.

30 Aug 2023

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

A team of researchers from Yale University and other institutions globally has developed an innovative patient triage platform powered by artificial intelligence (AI) that the researchers say is capable of predicting patient disease severity and length of hospitalization during a viral outbreak.

29 Aug 2023

Experts recommend brain aging biomarkers to improve brain health of elderly individuals

China and the world are facing severe population aging and an increasing burden of age-related diseases. Aging of the brain causes major age-related brain diseases, such as neurodegenerative diseases and stroke.

29 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

Could AI be the game-changer in remote Parkinson's diagnosis?

New AI tool for Parkinson's diagnosis outperforms certified raters and nearly matches experts, using webcam-captured videos of finger-tapping tests. The technology holds promise for remote, automatic diagnosis, especially in regions lacking neurological care.

28 Aug 2023

Online test nails early Alzheimer's diagnosis with biomarker precision

Researchers have developed a novel digital cognitive testing platform, using the Oxford Cognitive Testing Portal, that correlates with serological biomarkers to accurately measure cognitive impairment in Alzheimer's patients. The study highlights the platform's effectiveness in capturing subtle signs of impairment, potentially revolutionizing early diagnosis and tracking of Alzheimer's disease.

28 Aug 2023

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

A recent study in the Journal of Biomedical Science examines the critical role of ACE2, an enzyme involved in blood volume and electrolyte balance, in chronic diseases like cardiovascular conditions, diabetes, and COVID-19. The research suggests that ACE2 could serve as both a disease severity biomarker and a therapeutic target.

28 Aug 2023

Study discovers method to classify febrile illness with a single blood sample

Researchers trained machine learning (ML) models to analyze RNA molecular signatures in patients’ blood.

28 Aug 2023

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported Aug. 24 in the Journal of Clinical Investigation.

24 Aug 2023

Specific alterations in brain structural connectivity may be an early diagnostic marker for ASD

ASD, a complex neurodevelopmental disorder, is known to be linked to altered brain development. However, precise markers that can accurately diagnose ASD at the individual level have been elusive.

24 Aug 2023

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

New digital biomarker could detect Alzheimer's disease in its earliest stages

Researchers from the University of Colorado Anschutz Medical Campus and Washington University in St. Louis have identified a way to assess brain activity in sleep that occurs in the earliest stages of Alzheimer's disease, typically many years prior to developing symptoms of dementia.

23 Aug 2023

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

Researchers investigated the differential impact of HIV/tuberculosis co-infection on lipid and metabolic profiles.

23 Aug 2023

AI-powered protein score predicts major atherosclerotic cardiovascular disease events

In a large retrospective analysis using measurements of thousands of plasma proteins in primary and secondary event populations, scientists from deCODE genetics a subsidiary of Amgen and collaborators from USA, Denmark and Iceland, reported today in The Journal of the American Medical Association (JAMA) how they employed AI to develop a protein score to predict major atherosclerotic cardiovascular disease events (ASCVD).

22 Aug 2023

Simple blood test may predict risk of progressive heart and kidney disease in people with diabetic kidney disease

A simple blood test may predict the risk of progressive heart and kidney disease in people with Type 2 diabetes and kidney disease, according to new research published today in the American Heart Association's flagship journal Circulation.

21 Aug 2023

Biomarker News and Research

Further Reading

Blood NfL levels correlate with severity of Alzheimer's disease pathology

A type of gut bacteria may protect against the development of obesity and type-2 diabetes

The Clinical Importance of Circulating Tumor DNA

Parkinson's disease diagnosis could be made earlier with new blood test

Higher educational attainment may have a protective effect against Alzheimer's in people with genetic risk

Study detects significant levels of metals in the blood and urine among marijuana users

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

Experts recommend brain aging biomarkers to improve brain health of elderly individuals

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

Could AI be the game-changer in remote Parkinson's diagnosis?

Online test nails early Alzheimer's diagnosis with biomarker precision

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

Study discovers method to classify febrile illness with a single blood sample

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Specific alterations in brain structural connectivity may be an early diagnostic marker for ASD

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

New digital biomarker could detect Alzheimer's disease in its earliest stages

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

AI-powered protein score predicts major atherosclerotic cardiovascular disease events

Simple blood test may predict risk of progressive heart and kidney disease in people with diabetic kidney disease

Event guide: World Clinical Biomarkers & CDx Summit Japan eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo