Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Efficacy of glucosamine, chondroitin sulfate may depend on level of osteoarthritis pain

The popular dietary supplements glucosamine and chondroitin sulfate proved no better than a placebo in relieving osteoarthritis knee pain in most participants of a major national trial.

23 Feb 2006

Glucosamine/Chondroitin combo helps those with moderate to severe joint pain

According to a new study by the National Institutes of Health, people with moderate to severe joint discomfort found that a combination of glucosamine and chondroitin resulted in significant pain and function improvement.

23 Feb 2006

Radiologists more accurately identify damage to knee cartilage by using four radiologic 'signs'

Using the four signs to identify the extent and type of damage to knee cartilage makes interpreting MRIs with higher degrees of accuracy easier for any radiologist, regardless of their level of expertise.

21 Feb 2006

Innovative approach to cartilage repair

Leeds bioengineers have developed an innovative technique for cartilage repair combining the self-healing powers of the body with stem cell science to help young people avoid debilitating knee problems and give hope to arthritis sufferers.

2 Feb 2006

Deer antlers provide important clues for stem cell research

Research carried out by veterinary scientists at the Royal Veterinary College reveals that deer antler regeneration may use stem cells and involves similar mechanisms to those used in limb development.

2 Feb 2006

First-of-its-kind study in heart attack patients seeks to prevent heart failure with stem cells

University of Rochester Medical Center researchers have announced the launch of a study that will examine whether transplanted stem cells can be safely used to treat damaged heart muscle in patients just after their first heart attack.

23 Jan 2006

Evidence supports combination therapy for achieving remission of early rheumatoid arthritis

A chronic and potentially crippling inflammatory disorder, rheumatoid arthritis (RA) progressively wears away the cartilage and bone.

8 Jan 2006

Gene discovery may prevent craniofacial birth defects

Craniofacial researchers have developed an animal model that explains how skull malformations occur and how they might be prevented.

22 Dec 2005

Light at the end of the tunnel for arthritis sufferers

There is at last a light at the end of the tunnel for Arthritis sufferers.

21 Dec 2005

Hydrogels to potentially make chemotherapy and tissue regeneration more convenient and safe

Scientists at the Institute of Bioengineering and Nanotechnology (IBN) have invented an injectable and biodegradable gel that can deliver drugs at targeted sites or act as a scaffold for tissue repair.

15 Dec 2005

$Bone quality regulator identified - possible target for preventing and treating bone fractures$

Bone quality regulator identified - possible target for preventing and treating bone fractures

University of California - San Francisco (UCSF) scientists have determined that the quality of bone matrix, a key component of bone, is regulated by a molecule known as transforming growth factor beta.

13 Dec 2005

New insights into pain mechanisms

Long treated as a side effect, pain is now widely recognized as an integral part of patient care.

7 Dec 2005

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005

Lack of selenium increases risk of knee osteoarthritis

University of North Carolina at Chapel Hill Thurston Arthritis Center medical scientists and colleagues conducted the research. It focused on the knees of 940 participants enrolled in the Johnston County (N.C.) Osteoarthritis Project, a continuing, federally supported investigation of osteoarthritis that began 15 years ago and is headquartered at UNC.

20 Nov 2005

Scientists direct embryonic stem cells to become cartilage cells

Scientists from Imperial College London have successfully converted human embryonic stem cells into cartilage cells, offering encouragement that replacement cartilage could one day be grown for transplantation.

20 Nov 2005

Scientists use stem cells to grow cartilage

16 Nov 2005

Biomedical device allows stem cells derived from adult bone marrow to be grown in sufficient quantities to permit far more research

Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other human health problems.

14 Nov 2005

Increased physical activity may strenghten adult joint cartilage

Osteoarthritis (OA) is the leading cause of disability among adults. As the population ages, increased intervention efforts are vital to controlling the individual and public health toll of this chronic, crippling joint disease.

30 Oct 2005

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005