Cellular Biology News and Research

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Understanding focal adhesion kinase (FAK) may lead to new cancer treatments

Scientists at the University of North Carolina at Chapel Hill have found an unexpected way to turn off a cellular enzyme involved in the progression of several types of human cancers.

2 Jun 2004

Research laboratory at the forefront of the science of metabolomics

A new $1.8 million research laboratory will catapult Iowa State University to the forefront of the science of metabolomics.

2 Jun 2004

₤16.5 million investment in stem cell research

A ₤16.5 million investment in stem cell research was announced today, 27th May, promising to speed the development of new treatments and cures from the laboratory to the clinic. In total, 57 multidisciplinary research grants have been awarded as part of the new monies allocated via the 2002 Government Spending Review to the UK Research Councils.

27 May 2004

International adult stem cell 'retraining' project starts in Birmingham

An exciting research project to utilise the body's own stem cells to regenerate areas of tissue damage is uniting scientists in Birmingham, London and Ontario, Canada. The University of Birmingham is leading a three year study with long term aims of helping stroke, Parkinsons and diabetes patients.

27 May 2004

Toxoplasma gondii discovery may help fight against malaria

University of North Carolina at Chapel Hill scientists have discovered a protein in the cell wall of parasites that’s crucial to the molecular mechanism allowing them to move between cells, survive and cause disease.

25 May 2004

Researchers to develop a highly sensitive, portable method of detecting bioterror agents like anthrax

Their method uses "Cellular Analysis and Notification of Antigen Risks and Yields" (CANARY) cells, which are immune-system cells engineered to contain a fluorescent protein naturally found in jellyfish. CANARY cells have the immune system's ability to detect specific disease-causing agents, lighting up when they recognize a pathogen.

24 May 2004

Revolutionary self healing bandage that uses the patient's own cells

A revolutionary type of 'self healing' bandage that uses the patient's own cells is being developed. The technique has already been tried successfully on patients with diabetic ulcers and in the long-term could offer a more effective, quicker and cost efficient way of treating many types of slow-healing wounds such as pressure ulcers.

24 May 2004

Are we as crazy as mad cows?

When proteins in our body work properly, we can see, smell, consume and digest food, grow muscle and brain cells. But when these infinitely useful biological building blocks fail, the most pernicious diseases arise. Susan Lindquist has scrutinized the complex origami-like shapes of proteins and come to understand how structural mistakes can lead to a frightening class of neurodegenerative disorders, including “Mad Cow Disease.”

20 May 2004

Natural biological process by which yeast cells dismantle amyloid fibers

Amyloid fibers, those clumps of plaque-like proteins that clog up the brains of Alzheimer's patients, have perplexed scientists with their robust structures. In laboratory experiments, they are able to withstand extreme heat and cold and powerful detergents that cripple most other proteins.

20 May 2004

Cell division can be halted in multiple ways, with implications for cancer

Brown University researchers have found that there are multiple independent ways to stop cell division, a phenomenon that prevents the spread of genetic mutation, which can make cells cancerous. Results of this research, along with an accompanying editorial, were published in the current issue of the journal Molecular Cell.

20 May 2004

Scientists may have figured out how to use stem cells to regenerate lost or injured tissue

In experiments with fruit flies, Johns Hopkins scientists have restored the insect's sperm-making stem cells by triggering cells on the way to becoming sperm to reverse course. The unexpected findings are described in the May 13 issue of Science.

19 May 2004

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

The protein, torsinA, is defective in patients with DYT1 dystonia, an inherited condition that causes uncontrollable movements in the limbs and torso. Learning what torsinA does could be an important step toward developing a treatment for the disorder.

19 May 2004

Scientists move closer toward treatment for degenerative diseases

Scientists at McGill University's Faculty of Medicine have discovered a key step that will provide new targets for treatments of many degenerative diseases such as Alzheimer's, Cystic Fibrosis and Diabetes.

17 May 2004

Researchers make it possible to visualize memories

Researchers at Baylor College of Medicine in Houston have described how memories are made – and they have made it possible for you to see it.

15 May 2004

Strategy to treat obesity through molecular liposuction

Researchers at The University of Texas M. D. Anderson Cancer Center have designed a strategy to treat obesity through “molecular liposuction.” The therapy destroys blood vessels supporting fat accumulation — causing the fat to rapidly break down and disappear.

10 May 2004

New studies put spotlight on replicative capacity of beta cells

Researchers at Harvard University and the Howard Hughes Medical Institute (HHMI) have discovered that insulin-producing beta cells in the pancreas that are attacked in type 1 diabetes are replenished through duplication of existing cells rather than through differentiation of adult stem cells.

5 May 2004

Study suggests that the vitamins, such as E, C, and beta carotene, could raise bad form of cholesterol

The notion that antioxidant vitamins could provide a safe, convenient way to protect the heart from disease appears to have hit a pothole.

3 May 2004

New technique of identifying genes may help researchers developing drugs

A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature.

29 Apr 2004

A burst of brain energy depends more on a unique molecular cycle than on blood flow variation

A century old mystery is taking place in your head as you read these words. Blood vessels in regions of your brain are widening, bathing cells in an increased blood flow.

28 Apr 2004

Protein on the centrosome key to new strategies for stopping cancer growth

A Mayo Clinic discovery about a protein known as Dynamin-2 has thrown conventional wisdom for a loop. Finding the protein on the centrosome, a minute structure near a cell’s nucleus, may lead to new strategies for stopping cancer growth.

20 Apr 2004