Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

Perinatal maternal antibiotic exposure may impair lung development in premature infants

New research in mice suggests that exposure to antibiotics before birth may impair lung development in premature infants. The study, the first to explore the gut-lung axis in prematurity, is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology and was chosen as an APSselect article for December.

5 Dec 2019

Anti-hepatitis treatment also helps improve later complications

Hepatitis C is a serious disease, but the biggest threat to someone's health is not the virus itself. Rather, it is the diseases that can result from it such as reduced liver functioning, scar tissue in the liver and potentially cirrhosis.

5 Dec 2019

Georgia State professor selected as National Academy of Inventors Fellow

Jenny Yang, a Regents' Professor of chemistry at Georgia State University and the associate director of the Center for Diagnostics and Therapeutics, has been selected as a National Academy of Inventors (NAI) Fellow, the academy board announced on Tuesday.

5 Dec 2019

New technology developed for treatment of children suffering from respiratory diseases

A new technology to unblock and remove secretions from the respiratory tract of children has been developed as part of a collaboration between researchers at Ben-Gurion University of the Negev and its affiliated Soroka University Medical Center, Cincinnati Children's Hospital Medical Center, and the University of Cincinnati.

4 Dec 2019

New treatment approach could improve outcomes for people with cystic fibrosis

A new approach to treating people with cystic fibrosis (CF) has been shown to reduce inflammation, which has the potential to reduce the need for lung transplants and lower the risk of death.

3 Dec 2019

For artist inspired by illness, ‘gratitude outweighs pain’

People often ask Dylan Mortimer how it feels to breathe through transplanted lungs. He gets that a lot because while most people go through life with one pair of lungs, Mortimer is on his third.

2 Dec 2019

Research findings provide novel therapeutic space to induce scarless regenerative healing

Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix.

27 Nov 2019

State-of-the-art expert reviews provide insights into vitamin D research

Vitamin D is essential for human health. Although much is known about its important role in bone metabolism and in certain areas of non-skeletal health, there are many open questions and topics of debate.

27 Nov 2019

Dangerous bacteria send out warning signals when attacked by antibiotics

A bacterial infection is not just an unpleasant experience - it can also be a major health problem. Some bacteria develop resistance to otherwise effective treatment with antibiotics.

22 Nov 2019

Breakthrough therapy could improve health and survival in people with cystic fibrosis

Researchers at the Children's Hospital Colorado Breathing Institute, one of the largest cystic fibrosis clinical care centers in the U.S., are part of a Therapeutics Development Network that oversaw clinical trials leading to FDA approval of TRIKAFTA, a new, highly-effective CF treatment for people with CF 12 years of age and older.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

Rheumatoid arthritis linked to other diseases before and after diagnosis, shows study

A Mayo Clinic-led study involving 3,276 patients has found that people with inflammatory bowel disease, Type 1 diabetes or blood clots may be at increased risk of developing rheumatoid arthritis.

20 Nov 2019

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

The University of Barcelona and Hospital Clínic de Barcelona collaborate with Boehringer Ingelheim Inc. to improve the efficiency of nintedanib, an antiangiogenic and antifibrotic drug, for the treatment of lung cancer.

19 Nov 2019

Mysterious feather duvet lung disease nearly kills a man

A soft pillow and a warm duvet are all you need to have a soothing and relaxing sleep, especially during the frigid season. However, a man from the United Kingdom nearly died because of a mysterious illness related to a duvet. It was later found out by doctors that the culprit for his lung disease is his newly-bought feather duvet.

19 Nov 2019

Ammonia levels do not guide clinical management of hepatic encephalopathy in cirrhotic patients

The liver performs several critical functions including filtering blood, detoxifying chemicals and metabolizing drugs.

19 Nov 2019

Yale-led study provides roadmap to discover new treatment for idiopathic pulmonary fibrosis

A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the disease.

15 Nov 2019

UAB study suggests potential treatment target for IPF

Long-held dogma says lung fibrosis in diseases like idiopathic pulmonary fibrosis, or IPF, results from recurrent injury to alveolar epithelium that is followed by dysregulated repair.

12 Nov 2019

Study could open new avenues for antibacterial treatments

Scientists have revealed how common respiratory bugs that cause serious infections in people with cystic fibrosis interact together, according to a new study in eLife.

12 Nov 2019

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

The net clinical benefit of anticoagulants for atrial fibrillation (AF) -- one of the most important causes of irregular heartbeats and a leading cause of stroke -- decreases with age, as the risk of death from other factors diminishes their benefit in older patients, according to a study led by researchers at UC San Francisco.

11 Nov 2019

Fibrosis News and Research

Further Reading

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Perinatal maternal antibiotic exposure may impair lung development in premature infants

Anti-hepatitis treatment also helps improve later complications

Georgia State professor selected as National Academy of Inventors Fellow

New technology developed for treatment of children suffering from respiratory diseases

New treatment approach could improve outcomes for people with cystic fibrosis

For artist inspired by illness, ‘gratitude outweighs pain’

Research findings provide novel therapeutic space to induce scarless regenerative healing

State-of-the-art expert reviews provide insights into vitamin D research

Dangerous bacteria send out warning signals when attacked by antibiotics

Breakthrough therapy could improve health and survival in people with cystic fibrosis

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

Rheumatoid arthritis linked to other diseases before and after diagnosis, shows study

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

Mysterious feather duvet lung disease nearly kills a man

Ammonia levels do not guide clinical management of hepatic encephalopathy in cirrhotic patients

Yale-led study provides roadmap to discover new treatment for idiopathic pulmonary fibrosis

UAB study suggests potential treatment target for IPF

Study could open new avenues for antibacterial treatments

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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