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Calistoga Pharmaceuticals presents CAL-101 PI3K inhibitor data at European Hematology Association Congress

Calistoga Pharmaceuticals, Inc., the leader in the development of isoform-selective phosphatidylinositol 3 kinase (PI3K) inhibitors for the treatment of cancer and inflammatory diseases, today presented preclinical and clinical data on CAL-101, the Company's oral, delta selective PI3K inhibitor at the 15th Congress of the European Hematology Association in Barcelona, Spain.

14 Jun 2010

Ashikari Breast Center to participate in TARGiT intra-operative radiotherapy trial

The Ashikari Breast Center at The Dobbs Ferry Pavilion of St. John's Riverside Hospital today announced its participation in two new groundbreaking studies that may alter the care for early breast cancer.

11 Jun 2010

FDA advisory committee recommends approval of Novartis' FTY720 for relapsing MS

Today, an advisory committee of the US Food and Drug Administration (FDA) recommended approval of FTY720 (fingolimod) for the treatment of patients with relapsing multiple sclerosis, the most common form of the disease. The FDA has the option of seeking the advice of one of its advisory committees as it reviews and decides whether to approve a new treatment. The committee voted unanimously that FTY720 demonstrated substantial efficacy in treating relapsing remitting MS and that safety of the proposed 0.5 mg dose justified approval.

11 Jun 2010

HPV-positive tumor status is strong prognostic factor for head, neck cancer

Oropharyngeal cancer patients whose tumors in the upper part of the throat test positively for the human papillomavirus (HPV) have better overall survival than patients with HPV-negative disease, researchers from The University of Texas MD Anderson Cancer Center report in a study published in The New England Journal of Medicine.

8 Jun 2010

Targeted therapy that benefits patients with metastatic colon cancer fails to help patients with stage III cancer

To the surprise of researchers at Mayo Clinic who led a national clinical trial, a targeted therapy that provides benefit to patients with metastatic colon cancer has failed to help patients with less advanced, stage III cancer. In fact, patients who used the agent, cetuximab, with chemotherapy had outcomes slightly inferior to patients treated with chemotherapy alone.

7 Jun 2010

Addition of sorafenib to chemotherapy regimen not effective against advanced melanoma: Study

The combination of two different chemotherapies and a previously approved treatment for kidney and liver cancers is not effective against advanced melanoma, according to results disclosed in an oral presentation today at the 46th annual meeting of the American Society of Clinical Oncology in Chicago.

7 Jun 2010

New molecular imaging agent improves diagnosis of recurrent prostate cancer

Findings of a clinical trial reported at SNM's 57th Annual Meeting indicate that a new molecular imaging agent could improve diagnosis of recurrent prostate cancer and determine the best possible course of treatment for patients.

7 Jun 2010

Green tea component reduces leukemia cells in patients with CLL

An extract of green tea appears to have clinical activity with low toxicity in chronic lymphocytic leukemia (CLL) patients who used it in a phase II clinical trial, say researchers at Mayo Clinic.

5 Jun 2010

Radiation therapy may not improve chances of survival for bladder cancer patients: Study

In the largest study to date of a rare and deadly form of bladder cancer, researchers at Henry Ford Hospital in Detroit found radiation therapy may not improve a patient's chances for survival.

3 Jun 2010

PMRT increases breast cancer patients' five-year overall survival by almost 50%: Study

Postmastectomy radiation therapy for some breast cancer patients can reduce their risk of recurrence by almost 30 percent and increase their five-year overall survival by almost 50 percent, according to a study in the June 1 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology.

3 Jun 2010

NewYork-Presbyterian Hospital/Columbia University Medical Center announce presentations at American Urological Association meeting

Physician-scientists from NewYork-Presbyterian Hospital/Columbia University Medical Center will present their latest research findings at the American Urological Association Annual Meeting in San Francisco, May 29 to June 3.

31 May 2010

Patients with stage IIIA NSCLC who receive lobectomy have increased overall survival: Research

There's debate about the best treatment approach for patients with certain stages of non-small cell lung cancer, which accounts for about 80 percent of all lung cancers. Patients with early stages of NSCLC are typically treated with surgery, but those with stage IIIA present more of a challenge because they are such a diverse group.

29 May 2010

CytRx commences Phase 2 clinical trial of bafetinib for high-risk B-cell chronic lymphocytic leukemia

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced initiation of a Phase 2 proof-of-concept clinical trial to evaluate the preliminary efficacy and safety of its oncology drug candidate bafetinib in patients with high-risk B-cell chronic lymphocytic leukemia (B-CLL).

29 May 2010

Breast-conserving therapy is viable treatment option for African-American women: Researchers

Breast-conserving therapy is a viable treatment option for African-American women, although they tend to have more advanced breast cancer at diagnosis, according to researchers from Beaumont Hospitals, Royal Oak, Mich. The study is available online now and will be in the July 15 issue of the journal Cancer.

26 May 2010

Researchers determine critical role of bone marrow cells in fighting respiratory viruses

Researchers at Mount Sinai School of Medicine for the first time have determined that bone marrow cells play a critical role in fighting respiratory viruses, making the bone marrow a potential therapeutic target, especially in people with compromised immune systems. They have found that during infections of the respiratory tract, cells produced by the bone marrow are instructed by proteins to migrate to the lungs to help fight infection. The data are published in the current issue of Cell Host & Microbe.

25 May 2010

Poor survival rates in non-Hodgkin's lymphoma patients attributed to lifestyle factors

A new study led by researchers from Mayo Clinic in collaboration with six other U.S. institutions has found that patients with non-Hodgkin's lymphoma who smoked, consumed alcohol or were obese before their cancer diagnosis had poorer overall survival, compared to patients who did not have these risk factors.

24 May 2010

CINJ experts available to discuss prevention and treatment of skin cancer

As Memorial Day Weekend and the start of summer beach season fast approach, The Cancer Institute of New Jersey (CINJ) is making experts available to discuss the risks of developing skin cancer and what steps can be taken to prevent it.

24 May 2010

Live malaria parasites in the skin shut down immune responses and block vaccine function: Study

Why one after another new malaria vaccine tests well in the laboratory but fails in field trials has frustrated legions of malaria researchers, and has been the main stumbling block to malaria eradication. Now, a research team from Germany has unraveled that puzzle and shown that the problem is all about the skin and how it controls the immune system. The implications are profound.

20 May 2010

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.

20 May 2010

Tanning an addiction among young women

Amber Peterson, 31, used to visit tanning booths every other day for 10 years until she was diagnosed with the deadliest form of skin cancer at age 26. After surgery to remove the melanoma and several lymph nodes, this blond-haired, blue-eyed, fair-skinned woman is currently cancer-free. She has since traded in tanning beds for self-tanner in a bottle.

19 May 2010

Lymph Nodes News and Research

Calistoga Pharmaceuticals presents CAL-101 PI3K inhibitor data at European Hematology Association Congress

Ashikari Breast Center to participate in TARGiT intra-operative radiotherapy trial

FDA advisory committee recommends approval of Novartis' FTY720 for relapsing MS

HPV-positive tumor status is strong prognostic factor for head, neck cancer

Targeted therapy that benefits patients with metastatic colon cancer fails to help patients with stage III cancer

Addition of sorafenib to chemotherapy regimen not effective against advanced melanoma: Study

New molecular imaging agent improves diagnosis of recurrent prostate cancer

Green tea component reduces leukemia cells in patients with CLL

Radiation therapy may not improve chances of survival for bladder cancer patients: Study

PMRT increases breast cancer patients' five-year overall survival by almost 50%: Study

NewYork-Presbyterian Hospital/Columbia University Medical Center announce presentations at American Urological Association meeting

Patients with stage IIIA NSCLC who receive lobectomy have increased overall survival: Research

CytRx commences Phase 2 clinical trial of bafetinib for high-risk B-cell chronic lymphocytic leukemia

Breast-conserving therapy is viable treatment option for African-American women: Researchers

Researchers determine critical role of bone marrow cells in fighting respiratory viruses

Poor survival rates in non-Hodgkin's lymphoma patients attributed to lifestyle factors

CINJ experts available to discuss prevention and treatment of skin cancer

Live malaria parasites in the skin shut down immune responses and block vaccine function: Study

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Tanning an addiction among young women

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