Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Study provides novel insights into evolutionary pathways of pancreatic cancer

Pancreatic cancer is a form of cancer associated with the highest mortality rates in the world. Genetic changes that could explain his aggressiveness and early metastasis had not been found yet.

30 Jan 2018

Study finds specific protein that plays role in breast cancer metastasis

Researchers from the University of Liverpool have found an explanation for how breast cancer spreads to the lungs, which could potentially hold the key to preventing the progression of the disease.

25 Jan 2018

UCSF researchers find new way to attack common drivers of 'undruggable' cancers

Cancer researchers have made great strides in developing targeted therapies that treat the specific genetic mutations underlying a patient's cancer.

24 Jan 2018

Scientists discover new target for anti-angiogenic tumor therapy

Actively growing tumors have a high demand for oxygen and nutrients. Therefore, they stimulate the growth of blood vessels.

23 Jan 2018

Researchers block common siren call of glioblastoma and metastatic breast cancer

Aggressive cancers like glioblastoma and metastatic breast cancer have in common a siren call that beckons the bone marrow to send along whatever the tumors need to survive and thrive.

23 Jan 2018

Study identifies genes involved in latent asymptomatic state of breast cancer metastases

The time needed for breast cancer metastases (secondary lesions caused by cells that have escaped from the original tumor) to develop varies between patients, and little is known about the mechanisms that govern latency (the dormant state of cells that have already spread through the body).

23 Jan 2018

Study reveals key mechanism of how cancer metastasis happens

Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center researchers.

19 Jan 2018

Pretreatment improves outcomes in high-risk stage 3 melanoma, study shows

A pair of targeted therapies given before and after surgery for melanoma produced at least a six-fold increase in time to progression compared to standard-of-care surgery for patients with stage 3 disease, researchers at The University of Texas MD Anderson Cancer Center report in Lancet Oncology.

18 Jan 2018

Research sheds new light on genetic, environmental factors that promote prostate cancer metastasis

Prostate tumors tend to be what scientists call "indolent" - so slow-growing and self-contained that many affected men die with prostate cancer, not of it. But for the percentage of men whose prostate tumors metastasize, the disease is invariably fatal.

15 Jan 2018

Researchers discover new promising biomarker for colorectal cancer

Researchers from the University of Luxembourg found a new biomarker for colorectal cancer (CRC) that might improve therapy and survival rates of patients.

11 Jan 2018

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

9 Jan 2018

New way to identify breast cancer patients who may develop incurable secondary tumors

Scientists from King's College London, funded by Breast Cancer Now, believe they have found a way to identify lymph-node positive breast cancer patients who are most likely to develop incurable secondary tumours (metastases) and those who are less at risk.

9 Jan 2018

Researchers describe key cellular receptor involved in ovarian cancer metastasis

Researchers of the Molecular Signaling in Cancer group of the Oncobell program - proCURE Program have described a key cellular receptor in the processes of metastasis in ovarian cancer.

4 Jan 2018

Macrophages play major role in helping early breast cancer cells spread even before tumor develops

Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, potentially creating metastasis before a tumor has even developed, according to a study published in Nature Communications.

2 Jan 2018

Experts report new guidelines for clinical trial design in patients with brain metastases

Clinical trials of new anti-cancer therapies have often excluded patients whose disease has spread to the brain or central nervous system (CNS) or, if such patients were allowed on trial, trials have often failed to clearly capture information on the drug's effect in the brain.

30 Dec 2017

Research provides new understanding of how cancer cells move during metastasis

A University of Hawai'i Cancer Center researcher has identified how some cancer cells are made to move during metastasis. The research provides a better understanding of how cancer spreads and may create new opportunities for cancer drug development.

28 Dec 2017

Nanobiotix receives FDA approval for first immuno-oncology trial

NANOBIOTIX, a late clinical-stage nanomedicine company pioneering new approaches to the treatment of cancer, today announced the U.S. Food and Drug Administration has approved its Investigational New Drug Application for NBTXR3, a first-in-class nanoparticle designed for direct injection into cancerous tumors, activated by stereotactic ablative radiotherapy (SABR) and administered in combination with an anti-PD1 antibody (nivolumab or pembrolizumab).

26 Dec 2017

Metastasis News and Research

Further Reading

Study provides novel insights into evolutionary pathways of pancreatic cancer

Study finds specific protein that plays role in breast cancer metastasis

UCSF researchers find new way to attack common drivers of 'undruggable' cancers

Scientists discover new target for anti-angiogenic tumor therapy

Researchers block common siren call of glioblastoma and metastatic breast cancer

Study identifies genes involved in latent asymptomatic state of breast cancer metastases

Study reveals key mechanism of how cancer metastasis happens

Pretreatment improves outcomes in high-risk stage 3 melanoma, study shows

Research sheds new light on genetic, environmental factors that promote prostate cancer metastasis

Researchers discover new promising biomarker for colorectal cancer

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

New way to identify breast cancer patients who may develop incurable secondary tumors

Researchers describe key cellular receptor involved in ovarian cancer metastasis

Macrophages play major role in helping early breast cancer cells spread even before tumor develops

Experts report new guidelines for clinical trial design in patients with brain metastases

Research provides new understanding of how cancer cells move during metastasis

Nanobiotix receives FDA approval for first immuno-oncology trial

Nanomedicine platform can guide doctors to remove tumors and kill malignant cells

Study explores use of radiosurgery in lung cancer patients with multiple brain metastases

Study suggests new treatment option for most lethal form of breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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