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How the gut microbiome contributes to schizophrenia

Researchers explore potential relationships between schizophrenia, the gut microbiome, the gut-brain axis, and short-chain fatty acids.

19 Oct 2023

How do different organ microbiomes influence neuropsychiatric disorders?

Scientists review existing literature to understand how the microbiome influences neuropsychiatric disorders.

19 Oct 2023

Oral diabetes and obesity meds danuglipron and orforglipron show promise but have gastrointestinal drawbacks

New orally-administered GLP-1 receptor agonists danuglipron and orforglipron show promise in treating type 2 diabetes and obesity, according to a systematic review. While effective in glycemic control and weight reduction, these drugs come with gastrointestinal side effects that may lead to treatment discontinuation.

17 Oct 2023

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

The success and challenges of developing different tuberculosis (TB) vaccine types.

17 Oct 2023

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Whether inflammatory bowel disease (IBD) is causally related to extracolonic cancers.

17 Oct 2023

Paxlovid treatment provides protection against COVID-19 for both mother and child

A new mouse model of infection with the COVID-19-causing SARS-CoV-2 virus during pregnancy tracks closely the disease course doctors have observed in SARS-CoV-2-infected pregnant patients, and suggests that treatment with the antiviral Paxlovid provides protection for both mother and child.

16 Oct 2023

Investigational drug restores calcium levels in rare genetic disorder

An investigational drug, encaleret, restored calcium levels in people with autosomal dominant hypocalcemia type 1 (ADH1), a rare genetic disorder marked by an imbalance of calcium in the blood and urine, as well as abnormally low levels of parathyroid hormone, which regulates blood calcium levels.

13 Oct 2023

UCLA receives grant to improve liquid biopsy for early lung cancer detection

A team of investigators from the UCLA Jonsson Comprehensive Cancer Center and the UCLA School of Dentistry received a five-year $4.6 million grant from the National Cancer Institute to develop and improve liquid biopsy technologies for the early detection of lung cancer - the leading cause of cancer death in both men and women in the U.S.

13 Oct 2023

Early intervention with sublingual immunotherapy may lead to remission of peanut allergy

A three-year clinical trial funded by the National Institutes of Health and Food Allergy Research and Education (FARE) has shown that the sublingual immunotherapy, or SLIT, is safe in peanut-allergic children ages 1 to 4, with a greater likelihood of desensitization and remission the earlier the treatment began.

13 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Researchers in neuropsychopharmacology challenge conventional wisdom about antidepressants' actions, revealing significant intracellular activity that influences their effectiveness. Utilizing advanced technologies, the study prompts a reevaluation of drug targeting and mechanisms, opening new avenues for treating depression.

12 Oct 2023

New treatment option for hand osteoarthritis identified

Relief could be on the way for people with painful hand osteoarthritis after a Monash University and Alfred Health-led study found an affordable existing drug can help. Until now there has been no effective treatment.

12 Oct 2023

Generic PrEP use could reduce new HIV acquisitions, save lives among young men who have sex with men

Anne Neilan, MD, a physician-scientist in the division of Infectious Diseases at Massachusetts General Hospital is the senior author of a recently published paper in Clinical Infectious Diseases, Daily Oral HIV Pre-exposure Prophylaxis Among Young Men Who Have Sex With Men in the United States: Cost-Saving at Generic Drug Price.

12 Oct 2023

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

The oral manifestations of CD.

12 Oct 2023

Impact of caffeine consumption on oxidation of fats: common themes and future research

The association between caffeine consumption and fat oxidation.

12 Oct 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation.

11 Oct 2023

Do prebiotics and probiotics positively impact cardiovascular and renal health?

The benefits of consuming nutrients, prebiotics, and probiotics to enhance cardiovascular and renal health.

11 Oct 2023

Black Chokeberry (Aronia melanocarpa) diabetes benefits: Hope or hype?

Researchers compared the effects of fermented and non-fermented Aronia melanocarpa berries on glycemic markers in Type 2 Diabetes Mellitus patients. Despite the berries' high antioxidant potential and past studies suggesting benefits, this rigorous trial found no significant impact on waist circumference, insulin sensitivity, or glucose levels.

10 Oct 2023

New outreach campaign promotes collaboration between oral health providers and family physicians

An ongoing and open exchange between oral-health providers and family physicians can effectively improve the quality of their patients' treatment and wellbeing, and in certain cases even save lives.

10 Oct 2023

Oral News and Research

How the gut microbiome contributes to schizophrenia

How do different organ microbiomes influence neuropsychiatric disorders?

Oral diabetes and obesity meds danuglipron and orforglipron show promise but have gastrointestinal drawbacks

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Paxlovid treatment provides protection against COVID-19 for both mother and child

Investigational drug restores calcium levels in rare genetic disorder

UCLA receives grant to improve liquid biopsy for early lung cancer detection

Early intervention with sublingual immunotherapy may lead to remission of peanut allergy

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

New treatment option for hand osteoarthritis identified

Generic PrEP use could reduce new HIV acquisitions, save lives among young men who have sex with men

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

Impact of caffeine consumption on oxidation of fats: common themes and future research

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Do prebiotics and probiotics positively impact cardiovascular and renal health?

Black Chokeberry (Aronia melanocarpa) diabetes benefits: Hope or hype?

New outreach campaign promotes collaboration between oral health providers and family physicians

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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