Pathogen News and Research

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Molecular insights on the possible connection of SARS-CoV-2 and nicotinic acetylcholine receptors

A recent study assessed the mechanism by which SARS-CoV-2 Omicron and Alpha VOCs inhibit the SARS-CoV-2 spike protein and mitigate the risk of a multisystem inflammatory syndrome in children.

28 Feb 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

In a recent research report from the United States, currently available on bioRxiv* preprint server, scientists have shown that bacterial taxonomic and functional profiles can discriminate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status even without directly detecting viral transcripts – opening the door for entirely novel approaches in wastewater-based epidemiology.

27 Feb 2022

No seroprevalence observed against SARS-CoV-2 in wild ruminants in Germany

A team of scientists from Germany has recently conducted a serological screening on wild animals to assess seroprevalence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other pathogenic viruses related to domestic ruminants.

27 Feb 2022

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A new study discusses the emergence of new variants of SARS-CoV-2 that can escape antibody-mediated neutralization, as opposed to other Sarbecoviruses.

27 Feb 2022

Study uses 3D cervical organoids to show the danger of multiple infections

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models.

25 Feb 2022

Machine learning model identifies factors that contribute to antibiotic resistance in recurrent infections

A machine learning model built with data from thousands of patients with wound infections and urinary tract infections identified the factors that contribute to antibiotic resistance in recurrent infections.

24 Feb 2022

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Researchers demonstrated that decorating the capsid surface of adenovirus vaccine vectors with a newly discovered protein superglue, DogTag/DogCatcher generates potent SARS-CoV-2-specific humoral and cellular immunity.

24 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

A study recently published in the top-tier journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) shows how a specific gene flow from Neandertals can act as a double-edged sword by increasing the risk for the development of severe coronavirus disease 2019 (COVID-19), and at the same time decreasing the risk for the infection with the human immunodeficiency virus (HIV).

23 Feb 2022

Study suggests a broader approach to decrease the transmission of pathogens

Scientists have extensively studied water and sanitation interventions to decrease the transmission of pathogens and disease prevention.

23 Feb 2022

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

Scientists from Israel have recently estimated the levels of circulating microRNAs (miRNAs) in hospitalized coronavirus disease 2019 (COVID-19) patients with the aim of identifying prognostic biomarkers for disease severity. They have identified miR-155, an important regulatory molecule in the immune system, as a potential biomarker to predict COVID-19 severity and mortality.

22 Feb 2022

Pathogen News and Research

Molecular insights on the possible connection of SARS-CoV-2 and nicotinic acetylcholine receptors

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

No seroprevalence observed against SARS-CoV-2 in wild ruminants in Germany

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

Study uses 3D cervical organoids to show the danger of multiple infections

Machine learning model identifies factors that contribute to antibiotic resistance in recurrent infections

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

Study suggests a broader approach to decrease the transmission of pathogens

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

CD91 receptor promotes SARS-CoV-2 infection

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

Lung microbiome alterations and secondary-infections in lethal COVID-19

SARS-CoV-2 occurrence compared with other respiratory viruses in children with acute respiratory infections

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Study reports potently neutralizing mucosal IgA in saliva of BNT162b2 vaccine recipients

Pathogens in pneumonia-associated respiratory samples from Wuhan prior to SARS-CoV-2 emergence

Comparing the genomic landscapes of SARS-CoV-2 isolated from animal species relative to that in humans

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