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Researchers assess impact of coronavirus disease on individuals with progressive multiple sclerosis

Researchers conducting a large international study of progressive multiple sclerosis (MS) examined the impact of the global outbreak of coronavirus disease 2019 (COVID-19) on their study participants.

3 Sep 2020

Experimental drug for ALS shows promising results in clinical trial

An experimental medication slows the progression of the neurodegenerative disease called Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to recently released results from a clinical trial run by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital and Amylyx Pharmaceuticals, Inc., the company that manufactures the medication.

2 Sep 2020

Scientists aim to find cortisone alternatives with fewer side effects

Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19.

2 Sep 2020

Pharmaceutical researchers aim to create better CBD-like treatments

Cannabidiol (CBD) is an increasingly popular wellness trend. The compound, which occurs naturally in cannabis plants, is added to many products that claim to reduce anxiety, alleviate pain and more, without the intoxication of its cousin tetrahydrocannabinol (THC).

2 Sep 2020

Honeybee venom induces cancer cell death in aggressive breast cancer

The new study, published in the journal Nature Precision Oncology, highlights how bees can help combat breast cancer. The research team found that when the venom’s main component, when mixed with existing chemotherapy drugs, reduced tumor growth in laboratory mice.

2 Sep 2020

Scientists find promising drug candidates for treatment of motor neurone disease

Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease.

1 Sep 2020

Younger cycad seeds pose greater risk for toxicity, study reveals

University of Guam research has revealed that younger cycad seeds pose a greater risk for toxicity when consumed than more mature seeds, bringing the scientific community one step closer to understanding the origins of a neurodegenerative disease prevalent on Guam in World War II and closer to understanding related neurological disorders elsewhere.

31 Aug 2020

New dietary intervention improves pain and other symptoms in veterans with Gulf War Illness

A new study from American University shows the results from a dietary intervention in U.S. veterans suffering from Gulf War Illness, a neurological disorder in veterans who served in the Persian Gulf War from 1990 to 1991.

31 Aug 2020

'Jumping' DNA influences the differentiation, physiological functioning of neurons

The human genome contains over 4.5 million sequences of DNA called "transposable elements", these virus-like entities that "jump" around and help regulate gene expression.

28 Aug 2020

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Alberto Yáñez Boyer, Ramón y Cajal researcher at BIOTECMED (Interdisciplinary Research Structure in Biotechnology and Biomedicine) and the Department of Microbiology and Ecology at the University of Valencia (UV), participates in a study on the C9orf72 gene and its mutations in the immune system.

28 Aug 2020

New cellular pathway protects cells from infection by Ebola virus, coronaviruses

Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2.

28 Aug 2020

Potential link to brain inflammation may explain the connection between MS and fatigue

Up to 60 percent of patients with multiple sclerosis (MS) report that fatigue is the disease's most debilitating symptom.

27 Aug 2020

Study reveals neural mechanisms that contribute to fatigue in people with depression, MS, stroke

Scientists at Johns Hopkins Medicine using MRI scans and computer modeling say they have further pinpointed areas of the human brain that regulate efforts to deal with fatigue.

27 Aug 2020

Study reveals how a cannabinoid may treat acute respiratory distress syndrome

Acute Respiratory Distress Syndrome, when caused by a bacterial toxin known as Staphylococcal enterotoxin, can be completely prevented by treatment with Δ9-tetrahydrocannabinol (THC), a cannabinoid found in the cannabis plant.

26 Aug 2020

Inflammatory protein produced by mast cells contributes to fibrosis in gastric cancer

Gastric cancer, one of the leading causes of cancer-associated mortality worldwide, is renowned for its ability to disseminate throughout the peritoneal cavity.

26 Aug 2020

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers at Osaka University identify vicious cycle involving RNA exosome that accelerates disease progression in FTLD/ALS

24 Aug 2020

Study reveals a promising method for treating multiple sclerosis

A research team led by neurobiologist Professor Claire Jacob has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in degenerative diseases.

24 Aug 2020

Doctors with disabilities call for a paradigm shift to make medical education, profession more inclusive

Doctors treat and heal patients, but they are seldom seen as people who may themselves require care or accommodation. Medics with disabilities are now calling for a paradigm shift in this mindset to make medical education and the profession more inclusive.

21 Aug 2020

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

21 Aug 2020

Combining expertise in organoids and sequencing technologies for ALS research

MDC researchers received a $150,000 pilot project grant from the Chan Zuckerberg Initiative's Neurodegeneration Challenge Network to investigate a defining feature of amyotrophic lateral sclerosis (ALS).

20 Aug 2020

Sclerosis News and Research

Researchers assess impact of coronavirus disease on individuals with progressive multiple sclerosis

Experimental drug for ALS shows promising results in clinical trial

Scientists aim to find cortisone alternatives with fewer side effects

Pharmaceutical researchers aim to create better CBD-like treatments

Honeybee venom induces cancer cell death in aggressive breast cancer

Scientists find promising drug candidates for treatment of motor neurone disease

Younger cycad seeds pose greater risk for toxicity, study reveals

New dietary intervention improves pain and other symptoms in veterans with Gulf War Illness

'Jumping' DNA influences the differentiation, physiological functioning of neurons

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

New cellular pathway protects cells from infection by Ebola virus, coronaviruses

Potential link to brain inflammation may explain the connection between MS and fatigue

Study reveals neural mechanisms that contribute to fatigue in people with depression, MS, stroke

Study reveals how a cannabinoid may treat acute respiratory distress syndrome

Inflammatory protein produced by mast cells contributes to fibrosis in gastric cancer

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Study reveals a promising method for treating multiple sclerosis

Doctors with disabilities call for a paradigm shift to make medical education, profession more inclusive

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Combining expertise in organoids and sequencing technologies for ALS research

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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