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Fermented dairy products can improve gut mucosal immunity

In a recent study published in the journal Immunology Letters, researchers assessed the role of fermented dairy products and dairy starters in modulating gut mucosal immunity.

3 Nov 2022

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Researchers generated and characterized two monoclonal antibodies (NA8 and NE12) that target the receptor binding domain of the SARS-CoV-2 spike protein, and exhibit neutralizing activity against major SARS-CoV-2 variants of concern.

3 Nov 2022

Novel platform allowing universal off-the-shelf T and NK cell access shows potential for immunotherapies

Recent advances in immunotherapy for cancer have stimulated a plethora of studies aimed at developing T cells (white blood cells) and Natural Killer (NK) cells (immune cells with enzymes that can kill tumor cells or cells infected with a virus) in-vitro from pluripotent stem cells - cells that are able to self-renew by dividing and developing into the three primary groups of cells that make up a human body.

3 Nov 2022

Scientists identify a broadly neutralizing antibody against all dominant SARS-CoV-2 variants

Researchers in the United States identified a broadly neutralizing antibody (S728-1157 bnAb) that targets the receptor-binding site (RBS) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

Higher viscosity of extracellular fluid enhances cancer dissemination

New research findings show how higher viscosity, or resistance to flow, of the extracellular fluid that surrounds cells enables cancer cells to migrate more rapidly from a primary tumor to other sites in the body.

2 Nov 2022

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation.

1 Nov 2022

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Researchers examined virus-virus interactions using human lung cells coinfected with two co-circulating respiratory infection-causing viruses, respiratory syncytial virus (RSV) and influenza A virus (IAV).

1 Nov 2022

CHG may be the most effective irrigation solution for use during surgical treatment of bone tumors

The widely used disinfectant chlorhexidine gluconate (CHG) appears to be the most effective irrigation solution for use as part of the surgical treatment of bone tumors, suggests an experimental study in The Journal of Bone & Joint Surgery.

28 Oct 2022

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

SPK001, the first anti-SARS Cov2 monoclonal antibody candidate of SpikImm, a French biotechnology company founded by Truffle Capital, originally discovered by the Institut Pasteur's Human Immunology Laboratory, directed by Dr. Hugo Mouquet (Inserm Joint Research Unit), has been tested on three initial cohorts of healthy volunteers, and has demonstrated excellent tolerance, in the context of the Phase 1 clinical study, recently labeled as a "national priority" by CAPNET (National Steering Committee for Therapeutic Trials and other Research on Covid-19).

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Researchers fabricate a non-porous biodegradable vascular graft

Researchers developed a novel small-diameter biodegradable vascular graft that aids the formation of elastin-containing structures in the intima-media, which is important for the normal functioning of the artery.

26 Oct 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

In this interview, Dr. Shebna Massey discusses neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and more. She also discusses and explores new therapeutic targets and biomarkers for these diseases.

From Sino Biological Inc. 26 Oct 2022

Low meal frequency is suggested to decrease Alzheimer’s disease risk

Researchers evaluated the associations between low meal frequency (LMF) and Alzheimer’s disease (AD).

24 Oct 2022

What are the health benefits and food industry applications of wine industry by-products?

A new article reviewed the health benefits and food industry applications of the by-products of the wine industry.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

In a recent study posted to the medRxiv* preprint server, researchers in the United States assessed the efficiency of protection mediated by antibodies against symptomatic coronavirus disease 2019 (COVID-19) at low serum-neutralizing titers.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

in vivo News and Research

Fermented dairy products can improve gut mucosal immunity

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Novel platform allowing universal off-the-shelf T and NK cell access shows potential for immunotherapies

Scientists identify a broadly neutralizing antibody against all dominant SARS-CoV-2 variants

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

Higher viscosity of extracellular fluid enhances cancer dissemination

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

CHG may be the most effective irrigation solution for use during surgical treatment of bone tumors

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

Researchers fabricate a non-porous biodegradable vascular graft

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

Low meal frequency is suggested to decrease Alzheimer’s disease risk

What are the health benefits and food industry applications of wine industry by-products?

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

eBook: Using iPSCs models for human disease research and drug discovery eBook

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The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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