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Promising methods for early detection and treatment of rheumatoid arthritis

Rheumatoid arthritis is a chronic inflammatory autoimmune disorder that leads to significant health issues as well as high treatment costs. In this themed issue of Clinical Therapeutics, published by Elsevier, experts review multiple aspects of RA detection and intervention with the overall goal of moving the field closer to developing effective preventive measures.

10 Jun 2019

CGM evaluations in long-term islet transplant recipients show near-normal glycemic profiles

Continuous glucose monitoring evaluations in islet transplant recipients who have been insulin independent for an average of 10 years show near-normal glycemic profiles and time-in-range metrics, according to data presented by the Diabetes Research Institute at the University of Miami Miller School of Medicine.

10 Jun 2019

Researchers find more effective way to treat drug-resistant cancers

Researchers at SMU's Center for Drug Discovery, Design and Delivery have succeeded in lab testing the use of chemotherapy with a specific protein inhibitor so that the chemotherapeutic is better absorbed by drug-resistant cancer cells without harming healthy cells.

10 Jun 2019

Novel radiotracer can identify nearly 30 types of malignant tumors

A novel class of radiopharmaceuticals has proven effective in non-invasively identifying nearly 30 types of malignant tumors, according to research published in the June issue of The Journal of Nuclear Medicine.

10 Jun 2019

FDA authorizes marketing of first medical device for pain relief in adolescents with IBS

The U.S. Food and Drug Administration today permitted marketing of the first medical device to aid in the reduction of functional abdominal pain in patients 11-18 years of age with irritable bowel syndrome when combined with other therapies for IBS.

10 Jun 2019

Study raises the prospect of new therapies to delay muscle atrophy

Muscle decline caused by aging and certain diseases could be dramatically slowed by stopping a chain reaction that damages cells, new research shows.

10 Jun 2019

No lasting improvement in insulin secretion with diabetic medication

Adults with type 2 diabetes mellitus respond to medical treatment by producing more insulin, but there is no long-term effect on insulin secretion after treatment stops, concluded a pair of clinical trials.

9 Jun 2019

Bariatric surgery patients at higher risk of death from substance use problems

The death rate from drug- and alcohol-related causes in people who've had Roux-en-Y gastric bypass surgery is nearly triple that of the general public, according to University of Pittsburgh research published today in Surgery for Obesity and Related Diseases, the journal of the American Society for Metabolic and Bariatric Surgery.

8 Jun 2019

Longevity-related molecular programs do not last beyond midlife

Just as a computer requires code to work, our bodies are regulated by molecular "programs" that are written early in life and then have to do their job properly for a lifetime. But do they? It's a question that has intrigued researchers for years.

7 Jun 2019

New research provides welcomed news for countless patients taking PPIs

For patients taking proton pump inhibitors to treat gastroesophageal disease (GERD) or other acid-related conditions, new research puts safety concerns to rest.

7 Jun 2019

Researchers one step closer to unmasking the cause of familial MS

A new study has uncovered mutations in 12 genes that may be responsible for the familial type of multiple sclerosis (MS).

7 Jun 2019

Researchers move closer to finding the root cause of MS

An international team of researchers led by the University of British Columbia has made a scientific advance they hope will lead to the development of preventative treatments for multiple sclerosis.

7 Jun 2019

Three-drug combination could be effective therapy for people with advanced melanoma

A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced melanoma.

7 Jun 2019

CAPON protein may facilitate link between two most well-known Alzheimer's culprits

A new protein involved in Alzheimer's disease has been identified by researchers at the RIKEN Center for Brain Science.

7 Jun 2019

A million a day: STIs are a worldwide epidemic, declares WHO

STIs continue to rise globally, with more than 1 million new STIs of just four types being reported every day, according to a new report from the World Health Organization (WHO). This comes to over 376 million new STIs a year among people between 15 and 49 years.

6 Jun 2019

Drugs designed with advanced computing technologies could help tackle hospital superbugs

Hospital superbugs such as MRSA or E.coli could soon be under attack from a new generation of drugs designed with the help of advanced computing technologies from STFC and IBM Research.

6 Jun 2019

Foods enhanced with proven health benefits are stuck in 'development limbo', GM expert says

Many of the tools for tackling the global epidemics of malnutrition, obesity and their associated health problems are already with us, but are stuck in ‘development limbo’, according to an expert in GM technology.

6 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Chemical changes in the brain may be associated with unexplained motor symptoms

A new study finds that people who have movement problems, symptoms that cannot be explained by an underlying disease, may have chemical changes in specific areas of the brain.

6 Jun 2019

Nanotechnology treatment reverses multiple sclerosis symptoms in mice

A nanotechnology treatment derived from bone marrow stem cells has reversed multiple sclerosis symptoms in mice and could eventually be used to help humans, according to a new study led by University of California, Irvine researchers.

6 Jun 2019