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Study identifies risk factors for vitamin D deficiency in kidney disease patients on dialysis

Vitamin D deficiency is almost universal among kidney disease patients who have low blood protein levels and who start dialysis during the winter, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The research identifies a group of patients who are at extremely high risk of being deficient in vitamin D and provides some clues as to why the deficiency occurs in these individuals.

26 Feb 2010

Pall Corporation announces next generation, 96-well AcroPrep Advance filter plates

Pall Corporation, a global leader in filtration, separation and purification, has introduced its next generation 96-well filter plate that delivers consistency and reproducibility in applications, such as neonatal screening and multiplexing. The Pall AcroPrep Advance filter plate employs new design features that provide uniform filtration rates, lowers hold-up volumes and ensures consistent sample/bead recovery from the wells.

From Pall Corporation 26 Feb 2010

Avoiding dairy products due to lactose intolerance may pose diet and health risks, say experts

People may avoid milk and other dairy products due to concerns about lactose intolerance, but eliminating these nutrient-rich foods may not only be unnecessary to manage the condition - it could impact diet and health, concludes a panel of experts assembled by the National Institutes of Health (NIH).

26 Feb 2010

Lab research targets 'estrogen-receptor positive' breast cancer cells; identifies key protein

In a laboratory study published in the journal Cancer Research, Scott & White Healthcare anatomic pathologist Arundhati Rao, M.D. is a co-investigator looking at the ways in which estrogen can interfere with how chemotherapy does its job in destroying breast cancer cells.

25 Feb 2010

Taxing unhealthy foods may promote healthy food choices

Recently, the Obama administration called for a total ban on candy and soda in the nation's schools. States are beginning to impose "sin taxes" on fat and sugar to dissuade people from eating junk food. Pricing strategies may well be a key to changing behavior, but others favor subsidies over punitive taxes, as a way to encourage people to eat fruits and vegetables and whole grains.

25 Feb 2010

Soy products meet nutritional needs of people with lactose intolerance

Today, nutrition experts and physicians who participated in the NIH Consensus Development Conference on Lactose Intolerance and Health released an important report that concluded individuals who ingest inadequate amounts of calcium and vitamin D because of real or perceived lactose intolerance need dietary advice to ensure appropriate intake of missing nutrients.

25 Feb 2010

Transplanting genetically modified adult stem cells into injured spinal cord increases movement recovery

Researchers at UTHealth have demonstrated in rats that transplanting genetically modified adult stem cells into an injured spinal cord can help restore the electrical pathways associated with movement. The results are published in the Feb. 24 issue of the Journal of Neuroscience.

25 Feb 2010

Retinitis Pigmentosa: Embryonic stem cells for replacement of diseased retinal cells and restoration of sight

An international research team led by Columbia University Medical Center successfully used mouse embryonic stem cells to replace diseased retinal cells and restore sight in a mouse model of retinitis pigmentosa. This strategy could potentially become a new treatment for retinitis pigmentosa, a leading cause of blindness that affects approximately one in 3,000 to 4,000 people, or 1.5 million people worldwide.

25 Feb 2010

Increase in anti-Apo A-I, anti-HDL and anti-CRP may lead to atherosclerosis in SLE patients

A study by researchers in Australia and the United Kingdom suggests that autoantibodies to fat binding proteins significantly increase in systemic lupus erythematosus (SLE) patients with active disease. This increase in anti-apolipoprotein (anti-Apo A-I), anti-high-density lipoprotein (anti-HDL), and anti-C-reactive protein (anti-CRP) may contribute to the development of atherosclerosis in SLE patients, placing them at risk for cardiovascular disease (CVD).

25 Feb 2010

FDA approves Pfizer's Prevnar 13 pneumococcal conjugate vaccine

Pfizer Inc. announced today that the United States Food and Drug Administration has granted approval for Prevnar 13™ (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]), the Company’s 13-valent pneumococcal conjugate vaccine.

25 Feb 2010

Five Prime Therapeutics receives milestone payment for selection of therapeutic program

Five Prime Therapeutics, Inc. today announced it received a milestone payment from Centocor Research & Development, Inc. for the selection of a therapeutic that will be pursued for immunology-related indications. Under the collaboration, FivePrime identified multiple potential therapeutic targets through screening its comprehensive proprietary protein library in cell-based assays that were focused on therapeutic pathways underlying specific immune and inflammatory disorders.

24 Feb 2010

BioMarin Pharmaceutical reports GAAP net income of $4.7M for fourth-quarter 2009

BioMarin Pharmaceutical Inc. today announced financial results for the fourth quarter and year ended December 31, 2009. GAAP net income was $4.7 million ($0.05 per diluted share) for the fourth quarter of 2009, compared to GAAP net income of $24.5 million ($0.21 per diluted share) for the fourth quarter of 2008, which included a $30.0 million payment from Merck Serono related to the approval of Kuvan in the EU.

24 Feb 2010

QR Pharma awarded patent covering use of Posiphen and analogs in treatment of DS

QR Pharma, Inc., a developer of novel drugs to treat Alzheimer’s disease (AD), announced today that it was issued U.S. Patent No. 7,625,942, a "Method of Treating Down Syndrome" by the U.S. Patent and Trademark Office. The '942 patent covers use of Posiphen and analogs to treat cognitive impairments associated with Down Syndrome (DS). This patent valuably expands upon the original Posiphen and analog patent that claims composition of matter and use of compounds to lower amyloid-β precursor protein (APP) and thereby treat dementia and Alzheimer’s disease (AD).

24 Feb 2010

Over-produced PKC-iota oncogene linked to poor pancreatic cancer patient survival

Researchers at the Mayo Clinic campus in Florida have found that PKC-iota (PKC), an oncogene important in colon and lung cancers, is over-produced in pancreatic cancer and is linked to poor patient survival. They also found that genetically inhibiting PKC in laboratory animals led to a significant decrease in pancreatic tumor growth and spread.

24 Feb 2010

Arsenic exposure may increase cancer risk, says study

Researchers have found a new oncogenic signaling pathway by which the environmental toxin arsenic may lead to adverse health effects, including bladder cancer. These study results are published in Cancer Research, a journal of the American Association for Cancer Research.

24 Feb 2010

Research may lead to new therapeutic treatments for Huntington's disease

Huntington's disease (HD) is a cruel, hereditary condition that leads to severe physical and mental deterioration, psychiatric problems and eventually, death. Currently, there are no treatments to slow down or stop it. HD sufferers are born with the disease although they do not show symptoms until late in life.

24 Feb 2010

Genetic link between schizophrenia and autism may help study effectiveness of drugs for both illnesses

A genetic link between schizophrenia and autism is enabling researchers to study the effectiveness of drugs used to treat both illnesses.

24 Feb 2010

New genetic data may help predict risk for end-stage kidney disease

Israeli and American researchers have identified new genetic data that could be used in the future to predict who will develop end-stage kidney disease (ESKD). ESKD requires dialysis or transplantation to sustain life, and is fatal in most regions of the world, where these treatments are not available.

24 Feb 2010

Winner of 2010 Anatrace Membrane Protein Award

Affymetrix, Inc. today announced that Professor Tom Rapoport of Harvard Medical School and Howard Hughes Medical Institute is the winner of the 2010 Anatrace Membrane Protein Award.

24 Feb 2010

Presence of SIBLING proteins in premalignant oral lesions may predict oral cancer

The presence of certain proteins in premalignant oral lesions may predict oral cancer development, Medical College of Georgia researchers said.

24 Feb 2010

G Protein News and Research

Study identifies risk factors for vitamin D deficiency in kidney disease patients on dialysis

Pall Corporation announces next generation, 96-well AcroPrep Advance filter plates

Avoiding dairy products due to lactose intolerance may pose diet and health risks, say experts

Lab research targets 'estrogen-receptor positive' breast cancer cells; identifies key protein

Taxing unhealthy foods may promote healthy food choices

Soy products meet nutritional needs of people with lactose intolerance

Transplanting genetically modified adult stem cells into injured spinal cord increases movement recovery

Retinitis Pigmentosa: Embryonic stem cells for replacement of diseased retinal cells and restoration of sight

Increase in anti-Apo A-I, anti-HDL and anti-CRP may lead to atherosclerosis in SLE patients

FDA approves Pfizer's Prevnar 13 pneumococcal conjugate vaccine

Five Prime Therapeutics receives milestone payment for selection of therapeutic program

BioMarin Pharmaceutical reports GAAP net income of $4.7M for fourth-quarter 2009

QR Pharma awarded patent covering use of Posiphen and analogs in treatment of DS

Over-produced PKC-iota oncogene linked to poor pancreatic cancer patient survival

Arsenic exposure may increase cancer risk, says study

Research may lead to new therapeutic treatments for Huntington's disease

Genetic link between schizophrenia and autism may help study effectiveness of drugs for both illnesses

New genetic data may help predict risk for end-stage kidney disease

Winner of 2010 Anatrace Membrane Protein Award

Presence of SIBLING proteins in premalignant oral lesions may predict oral cancer

Industry Focus eBook - Cell biology (5th edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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