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SHARPIN protein regulates human cell activity

The research teams headed by Prof. Johanna Ivaska (University of Turku and VTT Technical Research Centre of Finland) and Prof. Marko Salmi (University of Turku and the National Institute for Health and Welfare) have discovered that the SHARPIN protein regulates human cell activity.

17 Nov 2011

New collaboration enables information sharing to aid in development of TB drug candidates

In this post in the Global Health Technologies Coalition's "Breakthroughs" blog, Heather Ignatius, senior policy manager for the TB Alliance, writes that while "the most recent WHO TB Control report noted that rates of tuberculosis (TB) declined this past year for the first time in decades, ... TB remains one of the most devastating global health crises today, with ripple effects that extend beyond health to cripple prosperity and development of regions overwhelmed by the disease."

17 Nov 2011

More risk of health problems in lean children who become obese as adults

Link between NRXN3 gene and impulsivity

Being impulsive can lead us to say things we regret, buy things we really don't need, engage in behaviors that are risky and even develop troublesome addictions. But are different kinds of hastiness and rashness embedded in our DNA? A new study suggests the answer is yes -- especially if you're a man.

17 Nov 2011

Breakthrough in loading gold nanorods into cells could lead to new cancer treatment

Rice University chemists have found a way to load more than 2 million tiny gold particles called nanorods into a single cancer cell. The breakthrough could speed development of cancer treatments that would use nanorods like tiny heating elements to cook tumors from the inside.

17 Nov 2011

Dipyrone may reduce brain damage after stroke

An older nonsteroidal anti-inflammatory drug (NSAID) called dipyrone may offer a new approach to reducing injury to brain tissue after a stroke, according to a study in the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

17 Nov 2011

GOP hopefuls tied in Iowa poll

Fifty-eight percent of that poll's respondents said they would "rule out" a candidate who has favored a mandate to buy health insurance. In other news, a separate poll found 47 percent of Americans would support doing away with the health law. Meanwhile, protestors make their opinions known to Herman Cain and Mitt Romney.

17 Nov 2011

Study finds Medicare changes would impose additional costs on majority of 'healthy' beneficiaries

Several deficit-reduction committees have suggested changing the federal health-care program for seniors to combine the hospital- and doctor-services deductibles that participants currently pay separately. In this system, seniors could have a $550 annual deductible, and be required to pay 20 percent toward all services up to a $5,550 annual limit.

17 Nov 2011

Incyte receives FDA approval for Jakafi to treat intermediate or high-risk MF

Incyte Corporation today announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Jakafi (ruxolitinib) for the treatment of patients with intermediate or high-risk myelofibrosis (MF), including primary MF, post-polycythemia vera MF and post-essential thrombocythemia MF.

17 Nov 2011

Excessive vitamin D levels can lead to onset of AF

While previous studies have linked vitamin D deficiency to an increased risk for cardiovascular disease, new research at the Intermountain Medical Center Heart Institute shows that too much vitamin D can lead to the onset of a dangerous heart condition known as atrial fibrillation.

16 Nov 2011

Budding yeast helps make useful predictions about the biology of individuals

It now only costs a few thousand Euros to sequence the genome of an individual human. However, for most of us, knowing our genome sequence would not be useful. Each human has more than 20 000 genes, and in each of us several thousand of these genes carry mutations.

16 Nov 2011

Equipping more state police cruisers with AEDs can save lives

Just 30 percent the nation's state police agencies reported that they equip their vehicles with automated external defibrillators, and of those, nearly 60 percent of said only a minority of their fleet have the lifesaving devices on board, according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the American Heart Association's annual Scientific Sessions.

16 Nov 2011

State roundup: Colorado uninsured/underinsured rate skyrockets; Georgia personhood resolution brewing

The Colorado Health Access Survey, a new report from The Colorado Trust and the Colorado Health Institute, has found that more than 1.5 million Coloradans – or nearly one in three residents – either have no health insurance or are underinsured, meaning they spend more than 10 percent of their income on out-of-pocket medical expenses. Just since the last survey two years ago, the percentage of employers offering health insurance has dropped to 57.8 percent this year from 63.7.

16 Nov 2011

Non-therapeutic antibiotic usage in food animals creates resistance genes, promotes antibiotic resistance

In a review study, researchers from Tufts University School of Medicine zero in on the controversial, non-therapeutic use of antibiotics in food animals and fish farming as a cause of antibiotic resistance.

16 Nov 2011

Leading alcohol researchers to discuss latest genetic findings at Loyola meeting

Leading alcohol researchers from the United States and Canada will discuss their latest findings at an all-day meeting Nov. 18 at Loyola University Chicago Stritch School of Medicine.

16 Nov 2011

New CAD test associated with higher rates of cardiac procedures, health-care spending

A new, noninvasive diagnostic test for coronary artery disease is associated with a higher rate of subsequent invasive cardiac procedures and higher health-care spending. That's according to an observational study of Medicare recipients conducted by researchers at the Stanford University School of Medicine.

16 Nov 2011

Boehringer Ingelheim bolsters drug discovery, development with $350M in capital investments

Boehringer Ingelheim Pharmaceuticals announced today that it has made more than $350 million worth of capital investments throughout its U.S. operations this year, in order to further bolster its drug discovery, development and manufacturing capabilities.

16 Nov 2011

Mirna reports new preclinical data of miRNA-based therapeutic candidate for hepatocellular carcinoma

Mirna Therapeutics, Inc., a biotechnology company pioneering microRNA replacement therapy for cancer, announced the presentation today of new preclinical data on the development of a miRNA-based therapeutic candidate for primary liver cancer at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in San Francisco, CA.

16 Nov 2011

Hearing loss affects one in five Americans: Study

A new study has shown that one out of five Americans that are 12 years or older, suffer from hearing loss. This new research was published in the Archives of Internal Medicine and is led by Frank R. Lin, of Johns Hopkins University. The study was based on data from the National Health and Nutritional Examination Surveys (NHANES) that has been gathered since 1971.

16 Nov 2011

Geron bows out of stem cell research

Geron Corp. is removing itself from the field it pioneered – stem cell research. Late Monday, the company said it would halt its study of a stem cell-based treatment for spinal cord injury, the first embryonic stem cell trial approved in the U.S.

16 Nov 2011

Research News and Research

SHARPIN protein regulates human cell activity

New collaboration enables information sharing to aid in development of TB drug candidates

More risk of health problems in lean children who become obese as adults

Link between NRXN3 gene and impulsivity

Breakthrough in loading gold nanorods into cells could lead to new cancer treatment

Dipyrone may reduce brain damage after stroke

GOP hopefuls tied in Iowa poll

Study finds Medicare changes would impose additional costs on majority of 'healthy' beneficiaries

Incyte receives FDA approval for Jakafi to treat intermediate or high-risk MF

Excessive vitamin D levels can lead to onset of AF

Budding yeast helps make useful predictions about the biology of individuals

Equipping more state police cruisers with AEDs can save lives

State roundup: Colorado uninsured/underinsured rate skyrockets; Georgia personhood resolution brewing

Non-therapeutic antibiotic usage in food animals creates resistance genes, promotes antibiotic resistance

Leading alcohol researchers to discuss latest genetic findings at Loyola meeting

New CAD test associated with higher rates of cardiac procedures, health-care spending

Boehringer Ingelheim bolsters drug discovery, development with $350M in capital investments

Mirna reports new preclinical data of miRNA-based therapeutic candidate for hepatocellular carcinoma

Hearing loss affects one in five Americans: Study

Geron bows out of stem cell research

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