BRCA1 Gene News and Research

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BRCA1 is a gene on chromosome 17 that normally helps to suppress cell growth. A person who inherits certain mutations (changes) in a BRCA1 gene has a higher risk of getting breast, ovarian, prostate, and other types of cancer.

Chemotherapy may benefit all women with a BRCA1 mutation

Breast cancer patients who possess one of the so-called "breast cancer" or BRCA genetic mutations do not have a higher risk of dying than patients with no BRCA mutations, according to a detailed study by researchers at the Technion-Israel Institute of Technology and the University of Toronto.

12 Jul 2007

Magnetic resonance spectroscopy for breast cancer

The American Cancer Society recently issued new recommendations for women with a higher risk of developing breast cancer, including those with a family history of breast or ovarian cancer, and those who may carry genetic mutations (BRCA1 or BRCA2) that make them more likely to develop the disease.

11 Jul 2007

Size of family appears to affect breast cancer risk

Researchers have found that the probability of the breast cancer gene mutation BRCA among women with a history of breast cancer is greater when the number of older, female relatives in the family is smaller, according to a study in the June 20 issue of JAMA: The Journal of the American Medical Association.

20 Jun 2007

Doubt cast on reliabilty of current models for breast cancer risk

A new study has challenged the accuracy of models currently used to predict a woman's risk of breast cancer.

20 Jun 2007

Discovery of IKBKE gene linked to breast cancer

Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers.

17 Jun 2007

New candidate breast-cancer susceptibility gene

Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania and the Dana-Farber Cancer Institute describe in this week's issue of Science a new candidate breast-cancer susceptibility gene.

28 May 2007

Detailed portrait of 700 proteins that help maintain DNA integrity

Cells have the remarkable ability to keep track of their genetic contents and -- when things go wrong, to step in and repair the damage before cancer or another life-threatening condition develops.

28 May 2007

Genome detectives discover four more breast cancer genes

An international team of scientists say they have identified another four genes that increase a woman's likelihood of developing breast cancer.

28 May 2007

Scientists 'home in' on new breast cancer genes

Cancer Research UK scientists have isolated five regions of the genome containing genes which can increase a woman's risk of developing breast cancer, reveals a major international study published online in Nature.

27 May 2007

New research may help identify patients most likely to benefit from cisplatin treatment

Researchers at the Massachusetts General Hospital (MGH) Cancer Center have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast tumors.

20 Apr 2007

Cancer genetic risk assessment for individuals at risk of familial breast cancer

Since recent medical findings have revealed that some families have increased breast cancer risk, a number of people are turning to cancer genetic services to learn more.

19 Apr 2007

New discoveries about stem cells in leukemia, breast and colon cancer

Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body.

19 Apr 2007

Health disparities in access to healthcare

Minority individuals are much more likely to develop and die from cancer than the general U.S. population.

16 Apr 2007

More women with family breast cancer history inquiring about MRI screening following ACS guidelines

More women with a family history of breast cancer are asking their physicians whether they should undergo breast magnetic resonance imaging scans after American Cancer Society guidelines released on Wednesday recommended the screening for women at high risk of developing the disease, the Baltimore Sun reports.

2 Apr 2007