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How multi-omics is changing what scientists can see in the human immune system

Human systems immunology is using multi-omics, single-cell tools, spatial technologies, and AI to decode immune responses across real-world human cohorts. The review highlights major opportunities for biomarker discovery and precision medicine, while stressing the need for rigorous study design, validation, and careful interpretation.

29 Apr 2026

Multiple myeloma mortality rates decline with advances in targeted therapies

A new research paper was published in Volume 17 of Oncotarget on April 28, 2026, titled "Targeted therapeutics and U.S. population-level mortality trends in multiple myeloma: A SEER-based analysis from 1975 to 2023."

29 Apr 2026

PCORI announces new funding for patient-centered clinical effectiveness research

The Patient-Centered Outcomes Research Institute (PCORI) today announced new funding to support patient-centered comparative clinical effectiveness research (CER) across a range of health conditions experienced by Americans, along with projects designed to help bring practice-changing CER results into real-world care settings.

28 Apr 2026

Experts establish new clinical trial endpoints for oligometastatic cancer

An international group of experts led by the Comprehensive Cancer Centre (CCC) at MedUni Vienna and University Hospital Vienna has established endpoints for clinical trials in patients with cancer and isolated metastases.

28 Apr 2026

NCCN publishes new patient guide for prostate cancer screening

The National Comprehensive Cancer Network® (NCCN®)-an alliance of leading cancer centers-has published a new book explaining the latest evidence and expert recommendations around prostate cancer screening.

28 Apr 2026

AI tool estimates biological age from photos to predict cancer outcomes

The Mass General Brigham research team behind FaceAge, an artificial intelligence (AI) tool that can estimate a person's biological age from a single photo, is reporting in a new study that estimating biological age from multiple photos taken over time can provide even more information about how well a person with cancer will do with treatment.

28 Apr 2026

New cord blood approach boosts survival in blood disease patients

A new way of using umbilical cord blood for treating blood diseases could make the treatment more accessible to patients who need a stem cell transplant.

27 Apr 2026

Researchers uncover new mechanism linking metabolism, immunity, and skeletal health

Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.

25 Apr 2026

Cell squeezing technology offers new breast cancer risk assessment

Researchers at City of Hope, a cancer research and treatment organization, and the University of California, Berkeley, have created a novel microfluidic platform that can assess women's breast cancer risk at the cellular level.

23 Apr 2026

Cancer during pregnancy causes lasting emotional and financial challenges

Women diagnosed with cancer in pregnancy face profound, long-term emotional and financial challenges, a new study from the University of Surrey finds.

22 Apr 2026

Early myocarditis onset after immunotherapy linked to higher fatality risk

Patients who developed myocarditis within the first month of receiving immune checkpoint inhibitor therapy were more likely to die of myocarditis, and myocarditis-specific fatality was more common in patients who experienced co-occurring myositis and myasthenia gravis, according to results from a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

21 Apr 2026

Ibuprofen shown to improve cognitive function in patients undergoing chemotherapy

Researchers have already shown that mild to moderate exercise can reduce "chemo brain," and a new study suggests that a low dose of an over-the-counter anti-inflammatory, ibuprofen, can also achieve positive results for cancer patients.

21 Apr 2026

AI model predicts immunotherapy response in lung cancer patients

A biology-guided artificial intelligence model applied to routine pathology slides accurately predicted outcomes and response to immunotherapy in patients with metastatic non-small cell lung cancer (NSCLC), according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

20 Apr 2026

Targeting glutamine metabolism enhances CAR-macrophage cancer therapy

Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function.

20 Apr 2026

Scientists disrupt key cancer proteins to target neuroblastoma

Researchers at Linköping University show how two important cancer-related proteins can be prevented from collaborating with each other.

20 Apr 2026

New study reveals CRISPR enzyme that responds to human DNA methylation

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of scientists from Wageningen University & Research and Van Andel Institute has identified a way to exploit this distinction. Using a variant of CRISPR, a modern tool for editing DNA, they distinguished tumor DNA from healthy DNA and selectively cut only the former. The study, published today in Nature, is an early but promising step toward a cancer therapy that targets and destroys tumor cells with high precision.

20 Apr 2026

Proteomics and AI bring earlier risk prediction into sharper focus

This review examines how high-throughput proteomics is expanding precision medicine by improving biomarker discovery, disease prediction, and drug development. It also shows how AI is helping researchers interpret complex proteomic data while highlighting major barriers such as standardization, validation, and clinical translation.

19 Apr 2026

Researchers use tiny glass capillaries to sample living cancer cell parts

A new analytical method could improve how cancer treatments are designed - by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates. Researchers from the University of Surrey and King's College London developed the method, which detects trace amounts of metal inside individual living cells and their internal compartments without the need to kill the cells first

17 Apr 2026

Scientists link poor sleep to decreased chemotherapy response via the gut

Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have made a startling discovery: The gut microbiota drives changes to the immune system caused by chronic sleep loss. These changes promote cancer progression, disrupt circadian rhythm and weaken the effectiveness of chemotherapy.

17 Apr 2026

Study explains the link between NDMA-contaminated water and childhood cancer

A new study from MIT suggests that a carcinogen that has been found in medications and in drinking water contaminated by chemical plants may have a much more severe impact on children than adults.

17 Apr 2026