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New insights explain the Treg paradox in colorectal cancer

In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.

15 Dec 2025

Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also affects other organs, including the brain, heart and gastrointestinal (GI) tract.

12 Dec 2025

Fear strongly influences pain perception in inflammatory bowel disease patients

Pain perception in affected individuals is more strongly influenced by learned fear than in healthy individuals. Changes along the gut-brain axis related to chronic inflammation may explain this.

12 Dec 2025

Study reveals how Ebola and Marburg viruses damage the human gut

Ebola (EBOV) and Marburg virus (MARV) are highly lethal viruses that cause severe disease in infected patients by extensively damaging the body.

11 Dec 2025

White bread vs wholegrain: which one is actually better for your health?

This review dispels common myths about white and wholegrain bread by examining their composition processing and health effects. It concludes that while wholegrain breads offer added benefits white bread remains a safe affordable and nutritionally meaningful staple when fortified.

11 Dec 2025

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

In a major step towards a precision therapy for Clostridioides difficile (C. diff) infection, researchers at The Hospital for Sick Children (SickKids) have uncovered how the body's bile acids bind to block C. diff's most dangerous toxin.

9 Dec 2025

Integrating AI into colon cancer diagnosis improves the speed and accuracy of detection

A recent study reveals that integrating Artificial Intelligence (AI) into colon cancer diagnosis over the past five years has significantly improved the speed and accuracy of the detection of the deadly disease.

8 Dec 2025

Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia

Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more than 85,000 patients.

7 Dec 2025

A personalized approach to treating pancreatic cancer

It's not surprising that pancreatic cancer is often referred to as a silent killer. With few early symptoms and an aggressive nature, it has one of the lowest survival rates of all cancers.

3 Dec 2025

Study provides new hope for future treatment of intestinal condition IBS

Researchers at örebro University in Sweden have made a significant advance in understanding the intestinal condition IBS.

2 Dec 2025

Why green tea delivers the strongest health benefits

This review examines tea's health effects, highlighting green tea's benefits for heart health and cognition, and warns about risks in processed tea products.

1 Dec 2025

Epigenetic drift explains why the aging intestine becomes more vulnerable to cancer

Researchers from the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena, Germany, the Molecular Biotechnology Centre (MBC) in Turin and the University of Turin, Italy, have discovered a fundamental mechanism of aging in the gut.

28 Nov 2025

Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

Study demonstrates a safer strategy for allogeneic stem cell transplants

In preclinical studies, researchers found that priming the immune system with a Treg-expanding therapy before stem cell transplant boosted survival, protected vital organs, and promoted a balanced gut microbiome-offering hope for safer, more effective treatment of blood cancers.

27 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

Toxin-secreting gut bacterium emerges as a driver of ulcerative colitis

A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study. The findings suggest potential for new treatment strategies.

20 Nov 2025

AGA issues updated guidance for pharmacologic treatment of moderate-to-severe Crohn's disease

The American Gastroenterological Association (AGA) has released a comprehensively updated clinical guideline on the pharmacological management of moderate-to-severe Crohn's disease.

20 Nov 2025

Single-port robotic surgery transforms cancer care at NYU Langone Hospital—Long Island

After enduring seven prior abdominal surgeries, 64-year-old Joy Monetti from Islip was no stranger to painful procedures and lengthy recoveries.

17 Nov 2025

New approach revives DNA from historic medical tissues

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.

13 Nov 2025

Ultra-processed foods linked to precursors of early-onset colorectal cancer

Colorectal cancer used to be associated with old age, but diagnoses have become increasingly common in adults aged 50 or younger particularly in high-income countries like the United States.

13 Nov 2025