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New therapies and technologies provide hope for age-related fertility challenges

Scientists explore emerging strategies to combat reproductive aging, highlighting promising therapies and technologies to improve fertility in later life.

17 Dec 2024

Researchers gain new insights into the molecular changes leading to Rett syndrome

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions have gained new insights into the molecular changes leading to Rett syndrome, a severe neurological disorder caused by mutations in the MeCP2 gene encoding methyl-CpG binding protein 2 (MeCP2).

16 Dec 2024

Toxic chemical exposure in early life linked to behavioral problems in rats

Early life exposure to a class of endocrine-disrupting chemicals (EDCs) called polychlorinated biphenyls (PCBs) may lead to behavioral problems in rats, according to a new animal study published in the Journal of the Endocrine Society.

10 Dec 2024

Mapping blood system changes offers new hope for leukemia treatments

Researchers at University of California San Diego School of Medicine and their colleagues have developed the first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime.

6 Dec 2024

ACMG sets new lifelong guidelines for managing phenylalanine hydroxylase deficiency

Updated evidence-based clinical guidelines for phenylalanine hydroxylase deficiency diagnosis and management.

4 Dec 2024

Researchers identify brain circuit behind sexual rejection in females

A team from the Champalimaud Foundation (CF) has pinpointed a critical neural circuit for sexual rejection, identifying a set of brain cells that play a crucial role in determining whether a female accepts or rejects mating attempts based on her reproductive cycle.

25 Nov 2024

Maternal health complications on the rise in Illinois, study reveals

A new study from Northwestern Medicine reveals a troubling rise in severe maternal health issues and birth complications in Illinois from 2016 to 2023, closely linked to increases in chronic health conditions affecting pregnancy, such as high blood pressure, gestational diabetes, mental health disorders and especially obesity, which saw the largest increase in annual rates.

23 Nov 2024

First 'blueprint' of human skeletal development offers new insights into bone formation

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

21 Nov 2024

Antiseizure medications in pregnancy tied to child neurodevelopment risks

Researchers investigate how anti-seizure medication use during pregnancy may increase the risk of neuropsychological conditions in children.

20 Nov 2024

Experts evaluate plant-based diets for kids, urging nutritional care and supplementation

Plant-based diets for children and adolescents may offer health benefits but pose risks of nutritional deficiencies, requiring careful planning and professional oversight.

18 Nov 2024

New study links genetic mosaicism to lower Alzheimer’s risk in adults with Down syndrome

Study finds mosaicism in Down syndrome reduces Alzheimer's risk, providing new insights into genetic influences on cognitive decline and dementia progression.

8 Nov 2024

Low-sugar diet in early life reduces risk of chronic diseases in adulthood

A low-sugar diet in utero and in the first two years of life can meaningfully reduce the risk of chronic diseases in adulthood, a new study has found, providing compelling new evidence of the lifelong health effects of early-life sugar consumption.

1 Nov 2024

1950’s sugar rationing policies reduced risks of hypertension and diabetes

The study links early-life sugar exposure to chronic disease risk, suggesting that sugar restriction could enhance health and reduce diabetes and hypertension.

31 Oct 2024

Boosting Treg cells shows promise in preventing recurrent pregnancy loss

Recurrent pregnancy loss can be devastating and exert a major impact on women, their partners, and society more broadly, but currently there are few options for effective therapies.

29 Oct 2024

Understanding the impact of sperm DNA damage on IVF pregnancy risks

For the first time, researchers have linked specific frequent defects in sperm to risk of pregnancy complications and negative impacts on the health of the baby.

12 Oct 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

Childhood obesity: How the first 2,000 days hold the key to lifelong health

Researchers reveal that early life factors, especially within the first 2,000 days, play a critical role in shaping future obesity risk. Addressing these factors with integrated interventions could combat the global childhood obesity crisis.

26 Sep 2024

Study links youth prediabetes to increased pregnancy risks later in life

New research conducted at Columbia Mailman School of Public Health and Mount Sinai School of Medicine shows a link between prediabetes among young people and adverse pregnancy outcomes later in life.

24 Sep 2024

Research reveals only a few brain regions remain untouched by transition to motherhood

Research shows pregnancy triggers neuroanatomical changes in the brain, with decreased cortical volume and increased white matter integrity over gestation.

17 Sep 2024

Long-term exposure to traffic noise and air pollution linked to increased infertility risk

Researchers explore the associations between long-term exposure to road traffic noise, air pollution, and infertility in men and women.

9 Sep 2024