Messenger RNA (mRNA) News and Research

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Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses

Researchers conducted a forensic analysis of SARS-CoV-2-related coronaviruses (SARS2r-CoVs).

13 Jul 2022

NIH launches clinical trial evaluating an experimental vaccine to prevent Nipah virus infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched an early-stage clinical trial evaluating an investigational vaccine to prevent infection with Nipah virus.

11 Jul 2022

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

Kidney cancer accounts for only 4% of all cancers in the United States; however, its incidence has more than doubled since 1975, with the most common type being clear cell renal cell carcinoma.

8 Jul 2022

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

Researchers assessed the impact of SARS-CoV-2 envelope protein on the bromodomain and extraterminal domain (BET) proteins.

29 Jun 2022

Potential SARS-CoV-2 antivirals based on host miRNAs

A recent research paper posted to the bioRxiv* preprint server demonstrated micro ribonucleic acids (miRNAs) as potential antiviral options against various coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

21 Jun 2022

Study shows safety of COVID-19 vaccines for patients treated for hypothyroidism

Inactivated and mRNA COVID-19 vaccines appear to be safe for patients treated for hypothyroidism, according to a new study being presented at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

The frequency and nature of RNA errors in both SARS-CoV-2 and its vaccine

A recent article demonstrated that SARS-CoV-2 mutants and vaccine variability stem from ribonucleic acid polymerase inaccuracy.

6 Jun 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

RGS2 protein expression may explain reduced sense of smell in COVID

Researchers tested the hypothesis that anosmia in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals elevates the expression of the odorant receptor, a regulator of G protein signaling 2 (RGS2) in humans.

18 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Study shows efficacy of COVID-19 vaccine in people receiving cancer treatment

People undergoing active cancer treatment, including stem cell transplant, should receive the COVID-19 vaccine, according to a study published in JAMA Oncology.

11 May 2022

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

A new study published in the New England Journal of Medicine has discussed the efficacy and safety profile of the ZF2001 vaccine in adults, based on a randomized, placebo-controlled, multinational, double-blind phase 3 trial.

9 May 2022

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Researchers analyzed the inhibition of stress granules formation in cells infected by the human common cold coronavirus HCOV-OC43 and SARS-CoV-2.

5 May 2022

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

In a new study, researchers assessed the efficacy of a third dose of COVID-19 vaccine in anti-CD20 antibody-treated individuals.

4 May 2022

New method enables the structural analysis of RNA molecules

We live in a world made and run by RNA, the equally important sibling of the genetic molecule DNA. In fact, evolutionary biologists hypothesize that RNA existed and self-replicated even before the appearance of DNA and the proteins encoded by it.

3 May 2022

Higher vaccination coverage associated with lower rates of population-level COVID-19 mortality and incidence in the US

By using data representing 80% of the US population, researchers have found that increased vaccination coverage against COVID-19 can be linked to a reduced incidence of cases and deaths.

2 May 2022

Researchers test a method for delivering genetic material into the body to repair damaged heart muscle

A method for delivering genetic material to the body is being tested as a way to repair damaged heart muscle after a heart attack.

30 Apr 2022

Research highlights importance of booster vaccine doses to protect against all Omicron variants

In a recent study published in the Cell Host and Microbe journal, researchers examined the neutralization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1, BA.1.1, and BA.2 sublineages.

27 Apr 2022

Superior T-cell immunity in COVID vaccinated

A recent study published in the journal Public Library of Science (PLOS) ONE presented the T cell and humoral immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and infection against the SARS-CoV-2 original and mutant strains.

27 Apr 2022

Antibodies against the original strain of SARS-CoV-2 may not work as well with omicron

If you're wondering why after two vaccination doses and a booster shot, you still got sick from the omicron strain of the virus that causes COVID-19, one possible answer may have been found in a recent study by researchers at Johns Hopkins Medicine and the National Institute of Allergy and Infectious Diseases at the National Institutes of Health.

26 Apr 2022