Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

New compound shows promise in stopping breast cancer metastasis

Researchers from the University of Liverpool have created a biomedical compound that has the potential to stop the spread of breast cancer. A recently published paper details these early findings.

21 Jul 2023

Researchers discover NFIC molecule that may prevent pancreatic cancer

The pancreas, located behind the stomach, manages the energy supply in our body. It does so by secreting proteins (enzymes) responsible for glucose – the body's main fuel – reaching other organs when required and in the right amount.

21 Jul 2023

Six new Damon Runyon Clinical Investigators announced for 2023

The Damon Runyon Cancer Research Foundation has named six new Damon Runyon Clinical Investigators.

20 Jul 2023

Predicting bone metastases type in prostate cancer using MRI

Researchers investigated the differences in prostate MRI findings and clinical characteristics between patients with prostate cancer exhibiting bone metastases.

20 Jul 2023

Breast cancer and MEN1: exploring the connection

Researchers evaluated the role of Multiple Endocrine Neoplasia 1 (MEN1) messenger ribonucleic acid (mRNA) in breast cancer

17 Jul 2023

New drug could overcome resistance to CDK4/6 inhibitors in breast cancer

Brest cancer is the most common cancer in women. Among breast tumors that spread to other organs (develop metastasis), 70% belong to a variant, called luminal, whose cells are sensitive to the female sex hormones estrogen and progesterone. In fact, the tumor forms when these hormones order the cells to divide.

14 Jul 2023

New precision medicine trial shows promise for treating rare brain tumors

Papillary craniopharyngiomas (PCPs) are a rare type of brain tumor that cause substantial morbidity for patients.

13 Jul 2023

How does SARS-CoV-2 affect the placenta during pregnancy?

Researchers examine host responses to SARS-CoV-2 within the placenta using transcriptomics.

12 Jul 2023

Indigenous men with prostate cancer more likely to have metastasis, worse survival

Indigenous Peoples in Canada have higher illness rates and lower life expectancies than non-Indigenous Canadians.

10 Jul 2023

Researchers show how communication networks in the tumor microenvironment promote cancer growth

Tumors consist of both the actual, malignant cancer cells and healthy, non-transformed cells in the immediate environment.

7 Jul 2023

Single-cell RNA sequencing provides new insights into gastric cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

6 Jul 2023

Study identifies role of ROR1 in pancreatic cancer metastasis

Tumor-initiating cells, or cancer stem cells, are gaining attention in cancer therapy, as they can travel through the body and cause cancerous tumors at other sites through metastasis.

5 Jul 2023

Research establishes ERβ as a tumor suppressor in inflammatory breast cancer

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "ERβ as a mediator of estrogen signaling in inflammatory breast cancer."

3 Jul 2023

Mutations in AGC kinase motif linked to colorectal cancer growth

Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key enzymes to promote tumor growth, resist therapies, and hasten its spread from the original site to the bloodstream or other organs.

3 Jul 2023

Novel anti-cancer drug found to sensitize tumor cells to ferroptosis

A team of researchers led by Dr. Marcus Conrad from Helmholtz Munich discovered a novel anti-cancer drug, called icFSP1, which sensitizes cancer cells to ferroptosis.

28 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

In a significant development in the fight against fatal cancers, University of Otago researchers have pinpointed a key feature that leads to the aggressive spread of colon cancer.

26 Jun 2023

Breakthrough discovery could lead to new treatments for brain metastases

When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that a type of brain cell called astrocytes plays an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.

24 Jun 2023

BU study reveals crucial signaling pathway that drives head and neck cancers

Despite advances in defining the genomic characteristics of head and neck cancers, these malignancies continue to rank among the deadliest cancers with few targeted therapies available.

23 Jun 2023

New platform technology bridges the gap between microscopic analysis and multiplex imaging

Researchers at the Ludwig Center at Harvard have developed a platform technology for imaging that enables integration of the methods of microscopic analysis long employed in pathology laboratories with the visualization of multiple molecular markers in individual cells that is now rapidly advancing in research labs.

22 Jun 2023