Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

UT Health Science Center researchers Gabor Tigyi, MD, PhD, Harriet Van Vleet Endowment Professor in Basic Oncology Research, Junming Yue, PhD, associate professor in the Department of Pathology, Sue Chin Lee, PhD, in the Department of Physiology, and David Schwartz, MD, chair of the Department of Radiation Oncology, are part of a scientific leadership group awarded $20 million from the University of Tennessee-Oak Ridge Innovation Institute in partnership with Oak Ridge National Laboratory and the University of Tennessee, Knoxville, to develop new radiopharmaceutical therapies to treat cancer.

21 Feb 2024

Targeting the Hippo signaling pathway to treat systemic sclerosis

Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease.

21 Feb 2024

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis.

21 Feb 2024

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

A study led by the Center for Biomaterials and Tissue Engineering of the Universitat Politècnica de València, member of Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, in collaboration with the Instituto de Investigación Sanitaria La Fe and the University of Zaragoza proposes a novel approach to slow neuromuscular degeneration in patients with Amyotrophic Lateral Sclerosis.

20 Feb 2024

Exercise unleashes anti-inflammatory power against autoimmune diseases

The impact of exercise training on reducing inflammation in adolescents and adults with autoimmune diseases.

19 Feb 2024

Deep learning shines a new light on Parkinson's detection through the eye

Study demonstrates the potential of deep learning algorithms to predict Parkinson's disease (PD) through retinal fundus imaging, offering a non-invasive, early diagnostic tool.

18 Feb 2024

New study pinpoints key markers for Long COVID diagnosis

Study identifies elevated serologic responses and memory CD8+ T cell clonal expansion as key markers of Long COVID, offering insights into its pathology and potential diagnostic approaches.

18 Feb 2024

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

16 Feb 2024

Rabies in urban opossums signals health alert in São Paulo

A female White-eared opossum (Didelphis albiventris) found dead in 2021 in Bosque dos Jequitibás Park in the center of Campinas, one of the largest cities in São Paulo state, Brazil, died from rabies meningoencephalitis, according to a group of researchers at the University of São Paulo (USP) and Adolfo Lutz Institute (IAL), the regional reference laboratory, working with health professionals affiliated with public institutions in São Paulo city and Campinas.

16 Feb 2024

HBO's 'The Last of Us' fungal apocalypse, science fiction, not future reality

Researchers in "Emerging Infectious Diseases" debunk the scenario of a global fungal pandemic as depicted in HBO's 'The Last of Us,' citing slow fungal evolution and current pathologies as barriers to such an event.

15 Feb 2024

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects."

15 Feb 2024

Study links Agent Orange exposure to neurodegenerative diseases

Agent Orange, an herbicide used during the Vietnam War, is a known toxin with wide-ranging health effects.

14 Feb 2024

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field.

14 Feb 2024

Novel assay enhances pediatric cancer treatment by identifying clinically relevant gene fusions

Identification of specific gene fusions is critical for the successful targeted treatment of pediatric cancer patients.

13 Feb 2024

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain.

12 Feb 2024

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered.

9 Feb 2024

DDT exposure found to alter sperm epigenome in humans

In a study that signals potential reproductive and health complications in humans, now and for future generations, researchers from McGill University, the University of Pretoria, Université Laval, Aarhus University, and the University of Copenhagen, have concluded that fathers exposed to environmental toxins, notably DDT, may produce sperm with health consequences for their children.

9 Feb 2024

New treatment targeting aging cells could offer lasting relief for diabetic macular edema

Targeting senescent cells in the retina with a BCL-xL inhibitor shows promise as a durable treatment for diabetic macular edema, potentially offering long-term visual function improvements.

8 Feb 2024

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."

8 Feb 2024

Do lifestyle factors affect late-life cognition and dementia pathology impact?

Scientists from the Rush University Medical Center in Chicago, United States, investigated whether brain pathology related to dementia, such as cerebrovascular pathology, phosphorylated tau fibril tangles, and β-amyloid accumulation, modify the association between healthy lifestyle choices and cognition during the later years in life.

7 Feb 2024

Pathology News and Research

Further Reading

Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

Targeting the Hippo signaling pathway to treat systemic sclerosis

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

Exercise unleashes anti-inflammatory power against autoimmune diseases

Deep learning shines a new light on Parkinson's detection through the eye

New study pinpoints key markers for Long COVID diagnosis

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Rabies in urban opossums signals health alert in São Paulo

HBO's 'The Last of Us' fungal apocalypse, science fiction, not future reality

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

Study links Agent Orange exposure to neurodegenerative diseases

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Novel assay enhances pediatric cancer treatment by identifying clinically relevant gene fusions

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

DDT exposure found to alter sperm epigenome in humans

New treatment targeting aging cells could offer lasting relief for diabetic macular edema

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

Do lifestyle factors affect late-life cognition and dementia pathology impact?

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

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