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New study identifies genes that shape human brain features

What makes the human brain distinctive? A new study published July 21 in Cell identifies two genes linked to human brain features and provides a road map to discover many more.

21 Jul 2025

Novel polysaccharide from Albizzia julibrissin shows promise against pancreatic cancer

Albizzia julibrissin is a widely distributed plant in China. Its dried stem bark has been used in traditional oriental medicine to treat insomnia, diuresis, sthenia, ascaricide, and confusion.

21 Jul 2025

Myeloid cells play central role in immune response after polytrauma

Gaining insights into the complex pathways and key cell populations involved in immune dysregulation can aid the development of therapeutic approaches to treat polytrauma, which is associated with poor patient outcomes.

21 Jul 2025

Erythritol alters brain vessel function and may raise stroke risk

Study shows erythritol adversely affects brain microvascular cells, increasing oxidative stress and impairing nitric oxide production, linked to stroke risk.

21 Jul 2025

Microbial signals rewire immunity in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with particularly high prevalence in East Asia.

21 Jul 2025

Sperm RNA profiles could identify the best embryos for IVF

Findings on sperm RNA suggest new biomarkers for IVF success, potentially improving embryo selection and reducing cycles needed for desired fertility outcomes.

21 Jul 2025

DeNovix releases new CellDrop FLxi applications

DeNovix announces the release of three new cell counting applications for the CellDrop FLxi Automated Cell Counter.

From DeNovix Inc. 21 Jul 2025

Blocking GAPDH aggregation protects brain cells and opens new path for stroke therapy

In a mouse model of acute ischemic stroke, researchers showed that inhibiting the aggregation of GAPDH, either genetically or with a novel peptide, significantly reduced brain damage and improved neurological function. The findings highlight GAPDH aggregation as a promising therapeutic target for stroke intervention.

20 Jul 2025

AI turns old diabetes drug Halicin into a potent weapon against superbugs

Researchers found that Halicin, an AI-identified drug, effectively inhibited most multidrug-resistant bacteria except Pseudomonas aeruginosa. The study highlights Halicin’s broad-spectrum antibacterial potential and the transformative role of artificial intelligence in antibiotic discovery.

20 Jul 2025

Boosting gut-friendly foods may slow biological aging, large US study finds

Higher scores on a dietary index linked to gut microbiota health are associated with slower biological aging in US adults, according to a large cross-sectional NHANES study. The findings suggest that improving diet quality for gut microbial diversity may help reduce age-related disease risk.

20 Jul 2025

Zebrafish reveal how two genes independently drive sensory organ regeneration

Researchers identified that two cyclin D genes, ccndx and ccnd2a, independently regulate distinct stem and progenitor cell populations during zebrafish sensory organ regeneration. The findings reveal that regeneration can proceed via alternative pathways even when one gene is disrupted, providing new insight into tissue repair mechanisms.

20 Jul 2025

Ancient viral DNA found to regulate human gene expression

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression.

18 Jul 2025

Rare coexistence of APC and KRAS mutations observed in patient with FAP and endometrial cancer

Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial cancer.

18 Jul 2025

Lipoxygenase emerges as a promising antiviral agent against severe fever with thrombocytopenia syndrome

Severe fever with thrombocytopenia syndrome (SFTS) was reported in Asia, with a fatality rate that can reach as high as 50%.

18 Jul 2025

Developing AI-driven stem cell therapies to fight ovarian aging

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

18 Jul 2025

Intratumoral microbiota reshape our understanding of cancer biology

Intratumoral microbiota-the microbial populations residing within solid tumors-have emerged as pivotal components of the tumor microenvironment (TME), influencing tumor initiation, progression, and therapeutic outcomes.

18 Jul 2025

New biomarker ELL2 identified for early diagnosis and prognosis in sepsis

Sepsis is a life-threatening condition caused by organ dysfunction resulting from the body's dysregulated response to infection.

18 Jul 2025

Innovative dynamic biomarker system unlocks new pathways in thyroid cancer management

Differentiated thyroid carcinoma (DTC) is typically indolent, and some patients may be managed conservatively without immediate surgery.

18 Jul 2025

Emerging therapies reshape the future of AMD treatment

Age-related macular degeneration (AMD) remains a leading cause of vision loss globally, with significant advancements in treatment options for both dry and wet AMD.

18 Jul 2025

Ohio State chemists unlock easier path to develop key drug components

Chemists have developed a novel way to generate a variety of highly useful chemical building blocks by harnessing metal carbenes, suggests new research.

18 Jul 2025