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Bird flu virus detected in Alaskan polar bear

Researchers reported a natural infection of a highly pathogenic avian influenza A(H5N1) virus in a free-ranging juvenile polar bear in Alaska, highlighting the importance of wildlife health surveillance in detecting emerging pathogens.

2 Jul 2024

No organ is an island: Genetic study shows unique but interconnected aging markers

Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.

2 Jul 2024

Early detection of aggressive multiple myeloma through molecular analysis

Multiple myeloma is one of the most common forms of cancer of the immune cells in the bone marrow. It is considered incurable.

1 Jul 2024

Study finds genetic links between childhood weight gain and early puberty

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found.

1 Jul 2024

New weakness found in antibiotic-resistant Pseudomonas aeruginosa

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics.

1 Jul 2024

Researchers shine light on the nuanced functions and intricate regulatory methods of RNA editing

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.

28 Jun 2024

Gene therapy milestone at SickKids offers hope for children with SPG50 neurodegenerative disorder

When Michael Pirovolakis received an individualized gene therapy in a single-patient clinical trial at The Hospital for Sick Children (SickKids) in March 2022, the course of his condition was dramatically altered.

28 Jun 2024

ERC Advanced Grant aids study on ubiquitin in DNA repair and genome stability

Professor Helle Ulrich, Executive Director of the Institute of Molecular Biology (IMB) and professor at Johannes Gutenberg University Mainz (JGU), has been awarded an Advanced Grant from the European Research Council (ERC).

28 Jun 2024

AI identifies new high-risk subtype in endometrial cancer

An AI tool to classify histopathological images and differentiate between endometrial cancer subtypes.

28 Jun 2024

New study reveals rare genetic variants significantly increase atrial fibrillation risk

Researchers identified rare genetic variants that significantly increase the risk of atrial fibrillation, enhancing AF risk stratification by combining these with polygenic risk scores.

28 Jun 2024

PFDN6 protein could be a new target for colorectal cancer treatment

Researchers have identified a protein called PFDN6 that may play a role in the development and spread of colorectal cancer (CRC).

27 Jun 2024

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Led by Rice's Gang Bao and MD Anderson's Dr. Jeffrey Molldrem, the initiative aims to foster collaboration between the two institutions on fundamental and translational cancer research, to develop new technologies for cancer detection and therapy and to secure external funding in support of further research and training.

27 Jun 2024

Novel approach can make many more bacteria amenable to genetic engineering

Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species.

26 Jun 2024

Primerdesign launches new assay for norovirus detection in oysters

Primerdesign (part of the Novacyt Group), a company focused on the design, manufacture, validation and supply of real-time PCR kits and reagents, today launched the genesig® Easy_oys Detection Kit for Norovirus in oysters.

From Primerdesign 26 Jun 2024

“G900” gene enhancers may play a pivotal role in asthma-associated inflammation

Type-2 helper T (Th2) cells play intricate roles in the inflammatory response underlying asthma. Elevated levels of the protein GATA3 stimulate the maturation of these cells. Consequently, gene regions known as enhancers, which enhance the expression of the GATA3 gene, have been implicated in asthma-associated inflammation.

26 Jun 2024

Study provides resource for investigating diabetes-linked transcription factors

Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal Nature Communications, the study revealed common and tissue-specific molecular pathways regulated by HNF4A and HNF1A, two proteins that possess important functions governing the development and function of the pancreas and liver.

26 Jun 2024

Breakthrough biomarker predicts recurrence risk in clear cell renal cancer

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence.

25 Jun 2024

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

Beyond genes, new research explores mechanics and calcium signaling

Using animals to study heart disease doesn't always translate well to human health outcomes, and human heart cells available for research don't work outside the human body.

25 Jun 2024

Multi-regional sampling uncovers hidden complexity in liver cancer

A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR's Genome Institute of Singapore (GIS) and funded by the National Research Foundation Singapore (NRF) has discovered unexpected molecular heterogeneity even within the same liver tumors. More than 40% of HCC harbors more than one molecular subtype within the same tumor and in these, the clinical outcomes for the patients are best predicted by the most aggressive subtype.

25 Jun 2024