Small Molecules News and Research

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Research offers avenue for creating Alzheimer's and HIV therapeutics

A new advance by UCLA biochemists has brought scientists one step closer to developing treatments that could delay the onset of Alzheimer's disease and prevent the sexual transmission of HIV.

24 Jun 2011

Axxam receives ADDF grant to develop new therapeutics for Alzheimer's

The Alzheimer's Drug Discovery Foundation (ADDF) announced today that it has awarded a grant to Axxam SpA to develop small molecules to treat Alzheimer's disease by targeting inflammation.

23 Jun 2011

NJIT research professor's work on sugar-based chemicals tops ACS must-read list

NJIT Research Professor Mike Jaffe's recent book chapter about sugar-based chemicals is topping the American Chemical Society (ACS) book series' must-read list.

22 Jun 2011

Novel biomarker-development pipeline approach for human diseases

Researchers at Fred Hutchinson Cancer Research Center have demonstrated in mice that the performance of a novel biomarker-development pipeline using targeted mass spectrometry is robust enough to support the use of an analogous approach in humans.

20 Jun 2011

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

UCSF's Robert Blelloch, MD, PhD, has received the 2011 Outstanding Young Investigator Award from the International Society for Stem Cell Research, for his pioneering research on the role of molecular tools known as microRNAs in embryonic stem cells and cancer.

16 Jun 2011

Promising results from VX-770 and VX-809 Phase 2 study for cystic fibrosis

Vertex Pharmaceuticals Incorporated and the Cystic Fibrosis Foundation today announced promising results from an ongoing Phase 2 study evaluating combinations of VX-770 and VX-809, potential medicines designed to treat the defective protein that causes cystic fibrosis.

9 Jun 2011

FDA accepts Adamis IND for APC-100 to treat prostate cancer

Adamis Pharmaceuticals Corporation announced today that the FDA has accepted an Investigational New Drug (IND) application for APC-100 to treat prostate cancer (PCa).

9 Jun 2011

Preclinical study: Combination therapy of SPX-106 and D-tagatose reduces triglycerides and cholesterol

Spherix Incorporated, an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis, and providers of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, today announced that its drug candidate, SPX-106, achieved statistically significant reductions in triglycerides and cholesterol when administered in combination with D-tagatose for nine weeks to genetically engineered mice prone to dyslipidemia.

3 Jun 2011

Innovations in diagnosis and treatment for esophageal cancer

In recent years, the number of cases of adenocarcinoma of the esophagus (or gullet) has been on the rise. At the same time, however, new ways of treatment are improving the outlook for patients. In the current issue of Deutsches Ärzteblatt International, Angelika Behrens and her working group report on innovations in diagnosis and treatment.

27 May 2011

'Spongy' silicon biosensor shows promise for medical, security applications

Vanderbilt University engineers have created a "spongy" silicon biosensor that shows promise not only for medical diagnostics, but also for the detection of dangerous toxins and other tiny molecules in the environment.

27 May 2011

Berkeley Lab researchers aim to create biological circuits for synthetic biology

Taking a page from the book of San Francisco radio legend Scoop Nisker, biologists who find themselves dissatisfied with the microbes nature has provided are going out and making some of their own. Members of the fast-growing "synthetic biology" research community are designing and constructing novel organisms and biologically-inspired systems - or redesigning existing organisms and systems - to solve problems that natural systems cannot.

27 May 2011

BPD expands existing bioprocess and scale-up laboratory in Poway, CA

Biologics Process Development Inc., a wholly-owned subsidiary of Viropro, will double the size of its existing bioprocess- and scale-up laboratory in Poway, CA.

25 May 2011

Scientific evidence supports benefits of sunscreen usage to prevent skin cancer

The American Academy of Dermatology today reiterated the safety and effectiveness of sunscreens to protect against the damaging effects from exposure to ultraviolet (UV) radiation. As one component of a daily sun-protection strategy, sunscreen is an important tool in the fight against skin cancer, including melanoma, the deadliest form of skin cancer.

24 May 2011

PolyPid announces new drug delivery system and an innovative biodegradable bone void filler

PolyPid, a developer of innovative drug carriers, announced today the company’s flagship platform – PolyPid. PolyPid is a new, innovative family of drug carriers, based on a fusion between two known drug delivery systems: polymers and lipid-based systems. The new drug carriers enable long-lasting and controlled release of therapeutic drugs. The revolutionary, patented carrier can be tailored to almost any drug – small molecules, peptides, protein and nucleic acids-based drugs. The formulations can be pre-planned in order to achieve the desired release rate of the drug/s and the optimal duration, which can last up to several months.

23 May 2011

Scientists identify key protein behind drug-resistant leukemia

Acute lymphoblastic leukemia, or ALL, is the most common form of childhood cancer. While most children treated for this disease survive, in a subgroup of patients the disease does not respond to treatment.

19 May 2011

New York Academy of Sciences and Zeltia to host marine drug discovery forum on May 20, 2011

Substances produced by living organisms found in nature-so-called "natural products"-have played a critical role in the development of drugs for life-threatening conditions. The anticancer agent Taxol was sourced from a plant, penicillin from a fungus, and a number of recent breakthroughs have resulted in the development and approval of anticancer drugs derived from marine sources such as coral and sponges.

16 May 2011

UCSD scientists discover steroid hormone that inhibits brain inflammation

Researchers at the University of California, San Diego School of Medicine have discovered a steroid hormone that inhibits inflammation in the brain. The findings, to be published in the May 13 issue of the journal Cell, have implications for understanding the exaggerated inflammatory responses that are characteristic features of numerous neurodegenerative diseases.

13 May 2011

Enzon first quarter adjusted loss from continuing operations decreases to $4.2 million

Enzon Pharmaceuticals, Inc. today announced its financial results for the first quarter of 2011.

7 May 2011

Techne acquires Tocris Holdings

Techne Corporation announced today that it has acquired 100% ownership of Tocris Holdings Limited and subsidiaries, a leading supplier of reagents for non-clinical life science research.

3 May 2011

Bill & Melinda Gates Foundation announces 88 new winners under Grand Challenges Exploration program

The Bill & Melinda Gates Foundation today announced 88 new winners of US$100,000 each to support innovative research that has the potential to dramatically improve lives in some of the world's poorest countries. The funding, made possible through the Grand Challenges Exploration (GCE) program, will enable researchers worldwide to test unorthodox ideas that address persistent health and development challenges.

30 Apr 2011

Small Molecules News and Research

Research offers avenue for creating Alzheimer's and HIV therapeutics

Axxam receives ADDF grant to develop new therapeutics for Alzheimer's

NJIT research professor's work on sugar-based chemicals tops ACS must-read list

Novel biomarker-development pipeline approach for human diseases

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

Promising results from VX-770 and VX-809 Phase 2 study for cystic fibrosis

FDA accepts Adamis IND for APC-100 to treat prostate cancer

Preclinical study: Combination therapy of SPX-106 and D-tagatose reduces triglycerides and cholesterol

Innovations in diagnosis and treatment for esophageal cancer

'Spongy' silicon biosensor shows promise for medical, security applications

Berkeley Lab researchers aim to create biological circuits for synthetic biology

BPD expands existing bioprocess and scale-up laboratory in Poway, CA

Scientific evidence supports benefits of sunscreen usage to prevent skin cancer

PolyPid announces new drug delivery system and an innovative biodegradable bone void filler

Scientists identify key protein behind drug-resistant leukemia

New York Academy of Sciences and Zeltia to host marine drug discovery forum on May 20, 2011

UCSD scientists discover steroid hormone that inhibits brain inflammation

Enzon first quarter adjusted loss from continuing operations decreases to $4.2 million

Techne acquires Tocris Holdings

Bill & Melinda Gates Foundation announces 88 new winners under Grand Challenges Exploration program

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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