Immune System News and Research

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Galapagos, AbbVie announce extension of GLPG0634 clinical development collaboration

Galapagos NV and AbbVie announced today an extension of their GLPG0634 clinical development collaboration to include Crohn's disease. Galapagos will fund and complete a Phase 2 program in Crohn's disease, which is designed to facilitate rapid progression into Phase 3.

17 May 2013

Scientists unravel complex role of PBs in maintaining cellular homeostasis

As scientists learn more about processing bodies, granules present within normal cells, they are unraveling the complex role PBs play in maintaining cellular homeostasis by regulating RNA metabolism and cell signaling.

17 May 2013

New research reveals how endothelium maintains highly efficient barrier function

The endothelium, the cellular layer lining the body's blood vessels, is extremely resilient. Measuring just a few hundred nanometers in thickness, this super-tenuous structure routinely withstands blood flow, hydrostatic pressure, stretch and tissue compression to create a unique and highly dynamic barrier that maintains the organization necessary to partition tissues from the body's circulatory system.

17 May 2013

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells, in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

17 May 2013

Changes in specific proteins contribute to 'leaky-gut' wall

Scientists at Trinity College Dublin have made an important advance in understanding the biological factors that keep the lining of the gut wall intact. Associate Professor, Maria O'Sullivan at Trinity's School of Medicine and St James's Hospital and colleagues, showed that changes in specific proteins may contribute to a 'leaky-gut' wall which may have important implications for common chronic digestive diseases such as irritable bowel syndrome and inflammatory bowel disease.

17 May 2013

Preclinical study shows PLX cells may help reverse symptoms associated with preeclampsia

Could the answer to repairing the ailing placenta in preeclampsia lie within the stem cells of a healthy placenta? New promising evidence may lead scientists to answer that question.

17 May 2013

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

Northwest Biotherapeutics, a biotechnology company developing DCVax-L personalized immune therapies for solid tumor cancers, today announced that its Phase III clinical trial with DCVax-L for brain cancer has been initiated at King's College Hospital in the UK.

17 May 2013

Novel cell sorting enhancement to MoFlo Astrios platform to be introduced by Beckman Coulter Life Sciences at CYTO 2013

Two seminars and seven poster sessions, Beckman Coulter will have a prominent role when CYTO 2013 convenes at the San Diego Convention Center May 18-22, 2013.

From Beckman Coulter Life Sciences - Flow Cytometry 16 May 2013

LMU researchers reveal link between natural killer cells and hematopoiesis

Infections can trigger hematopoiesis at sites outside the bone marrow - in the liver, the spleen or the skin. Researchers at Ludwig-Maximilians-Universitaet in Munich now show that a specific type of immune cell facilitates such "extra medullary" formation of blood cells.

16 May 2013

Study suggests need for better anti-rejection therapies

Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in the Journal of Clinical Investigation.

16 May 2013

Simponi injection gets FDA approval to treat adults with ulcerative colitis

The U.S. Food and Drug Administration today approved a new use for Simponi (golimumab) injection to treat adults with moderate to severe ulcerative colitis.

16 May 2013

Magic bullet nanomedicine offers potential treatment option for Acute Lung Injury

Researchers at Queen's University Belfast have devised a 'magic bullet' nanomedicine which could become the first effective treatment for Acute Lung Injury or ALI, a condition affecting 20 per cent of all patients in intensive care.

15 May 2013

Bacteria form biofilm to protect against immune system

Bacteria are life forms, which, like all other life forms, struggle for the best living conditions for themselves. Therefore they will try to avoid getting attacked by the human immune system, and therefore they have developed various ways to protect themselves from the human immune system.

15 May 2013

Polymer substance fully resists the body's natural attack response to foreign objects

It's a familiar scenario - a patient receives a medical implant and days later, the body attacks the artificial valve or device, causing complications to an already compromised system.

15 May 2013

Better understanding of cells' development has implications in study of inflammatory diseases

Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells. Some researchers liken them to foot soldiers that protect boundary tissues such as the skin, the lining of the lung, and the lining of the gut from microbial onslaught. They also have shown they play a role in inflammatory disease, when the body's immune system is too active.

15 May 2013

Immune System News and Research

Galapagos, AbbVie announce extension of GLPG0634 clinical development collaboration

Scientists unravel complex role of PBs in maintaining cellular homeostasis

New research reveals how endothelium maintains highly efficient barrier function

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Changes in specific proteins contribute to 'leaky-gut' wall

Preclinical study shows PLX cells may help reverse symptoms associated with preeclampsia

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

Novel cell sorting enhancement to MoFlo Astrios platform to be introduced by Beckman Coulter Life Sciences at CYTO 2013

LMU researchers reveal link between natural killer cells and hematopoiesis

Study suggests need for better anti-rejection therapies

Simponi injection gets FDA approval to treat adults with ulcerative colitis

Magic bullet nanomedicine offers potential treatment option for Acute Lung Injury

Bacteria form biofilm to protect against immune system

Polymer substance fully resists the body's natural attack response to foreign objects

Better understanding of cells' development has implications in study of inflammatory diseases

ALKBH7 protein plays key role in controlling programmed necrosis pathway

Virginia Tech researchers identify leptospirosis as a major health threat in Botswana

India's DBT, Bharat Biotech announce positive Phase III clinical trial results of rotavirus vaccine

Inhibiting powerful protein with new agents may supply broad benefit for lymphoma patients

Implications for manipulating immune response for some inflammatory disorders

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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