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CRIPSR identifies cell-type-specific ACE2 modifiers

Researchers compile a list of candidate genes to identify the surface abundance of functional regulators of ACE2.

9 Mar 2022

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Sepsis is a high-mortality disease that arises when the body's immune reaction to pathogens causes multi-organ defects.

9 Mar 2022

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Researchers assessed the diabetogenic potential of SARS-CoV-2 in a single cell in vitro analysis on the pancreatic islet cells.

9 Mar 2022

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

A new study provides an overview of the use of mathematical modeling to determine severe acute respiratory syndrome coronavirus 2 kinetics.

9 Mar 2022

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

In a recent study posted to the bioRxiv* preprint server, researchers presented the intragenomic rearrangements of β-coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

9 Mar 2022

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Assessment of oligonucleotides as COVID-19 treatment

A recent study posted to the bioRxiv* pre-print server assessed the ability of oligonucleotides in preventing the development of infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions.

8 Mar 2022

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Leptomeningeal disease is a rare complication of several different types of cancer, including melanoma. It occurs when tumor cells migrate to the cerebrospinal fluid and the tissue that surrounds the brain and spinal column known as the meninges.

8 Mar 2022

Study suggests recent common cold may actually lead to worse COVID-19 disease

A new study published in the Journal of Infectious Diseases shines an unexpected light on the notion that pre-existing immunity to common cold coronaviruses can protect us from coronavirus disease 2019 (COVID-19) – and reveals that this may actually put certain individuals at risk of more severe clinical presentations.

8 Mar 2022

Researchers secure $12 million grant to develop improved therapies for hemophilia

An Indiana University School of Medicine researcher will lead a multi-institute effort toward improved therapies for hemophilia with help from a $12 million grant from the National Heart Lung and Blood Institute.

8 Mar 2022

Unusual partners are key to making more blood vessels

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

8 Mar 2022

A new view of SARS-CoV-2 genome structure

Researchers performed DMS mutational profiling with sequencing and DREEM clustering to determine the SARS-CoV-2 RNA secondary structure.

8 Mar 2022

How will mutations change the SARS-CoV-2 spike protein in the future?

A new Cells review discusses the factors that affect the function of the SARS-CoV-2 S protein and provides theoretical limits of this viral protein.

8 Mar 2022

Durable selenium nanoparticle fabrics with antiviral and antibacterial properties

Researchers graft SeNPs on polyester fabric through a flat screen-printing technique and observed their antimicrobial activity.

8 Mar 2022

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Scientists have shed new light on the role of the placenta in managing the relationships between maternal vitamin D and fetal development, according to a study published today in eLife.

8 Mar 2022

Researchers unravel how parent's gene impact the behavior of children

Parenting is not the only way moms and dads impact the behavior of their offspring. Genes matter, too. And although most of our genes are inherited in pairs - one copy from each parent - moms and dads exert their genetic influence in different ways.

8 Mar 2022

UH researchers receive grant for developing new imaging technique to peer into ribosomes

Two University of Houston researchers are developing a type of spectroscopy to help understand how ribosomes make proteins deep within cells, the discovery of which could potentially guide drug design to treat cancers and viral infections.

8 Mar 2022

Illinois Tech receives $2.17 million NIH grant to develop drug treatments for cholera

Illinois Institute of Technology is receiving a four-year grant from the National Institutes of Health to fund research to develop drug treatments for cholera and other multi-drug-resistant strains of disease-causing bacteria.

8 Mar 2022

Study reveals new insights on how immune system cells respond to disease-causing pathogens

In laboratory experiments involving a class of mutations in people with a rare collection of immune system disorders, Johns Hopkins Medicine researchers say they have uncovered new details about how immune system cells respond to disease-causing bacteria, fungi and viruses such as SARS-CoV-2.

8 Mar 2022

Cell News and Research

CRIPSR identifies cell-type-specific ACE2 modifiers

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

Assessment of oligonucleotides as COVID-19 treatment

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Study suggests recent common cold may actually lead to worse COVID-19 disease

Researchers secure $12 million grant to develop improved therapies for hemophilia

Unusual partners are key to making more blood vessels

A new view of SARS-CoV-2 genome structure

How will mutations change the SARS-CoV-2 spike protein in the future?

Durable selenium nanoparticle fabrics with antiviral and antibacterial properties

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Researchers unravel how parent's gene impact the behavior of children

UH researchers receive grant for developing new imaging technique to peer into ribosomes

Illinois Tech receives $2.17 million NIH grant to develop drug treatments for cholera

Study reveals new insights on how immune system cells respond to disease-causing pathogens

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