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Biogen Idec and Swedish Orphan Biovitrum commence dosing in rFIXFc Phase I/IIa trial for hemophilia B

Biogen Idec and Swedish Orphan Biovitrum today announced that the first patient was dosed in a registrational, open-label, multicenter trial designed to evaluate the safety, pharmacokinetics and efficacy of the companies’ long-acting, recombinant Factor IX Fc fusion protein (rFIXFc) in hemophilia B patients.

25 Jan 2010

Researchers identify new gene signature that predicts cancer recurrence in certain breast tumors

Researchers at Dana-Farber Cancer Institute have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumors that have been treated with commonly used chemotherapy drugs.

24 Jan 2010

Loss of key proteins may account for molecular abnormalities associated with myotonic dystrophy

Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins.

24 Jan 2010

New technology may allow scientists to monitor real time activity of protein network

A new assay capable of examining hundreds of proteins at once and enabling new experiments that could dramatically change our understanding of cancer and other diseases has been invented by a team of University of Chicago scientists.

24 Jan 2010

Healthy eating trend fuels probiotic yogurt sales

Call it “the sweet spot.” The Greek Gods Yogurt is in the enviable target zones where yogurt sales are domestically growing most. In its most recent Nov. 2009 report, Mintel’s industry data found the probiotic and protein-packed Greek Gods Yogurt brand situated in yogurt’s most evident growth segments.

23 Jan 2010

U.S. blood banks have sufficient blood to meet the needs of Haiti victims

The AABB Interorganizational Task Force on Domestic Disasters and Acts of Terrorism has determined that the current blood supply in the United States is adequate to fill any requests received to support the present needs of Haitian hospitals, though ongoing infrastructure and transportation issues in Haiti could delay receipt of those supplies to patients.

23 Jan 2010

Study of 16INK4A gene's role in progression of retinoblastoma

Retinoblastoma is a pediatric eye cancer initiated by the loss or mutation of both copies of the retinoblastoma gene. Current evidence suggests that additional genetic alterations are required for retinoblastoma to become fully malignant.

23 Jan 2010

Study: Warburg effect promotes rapid cell proliferation and tumor growth

A team of scientists led by Professor Adrian Krainer, Ph.D., of Cold Spring Harbor Laboratory has discovered molecular factors in cancer cells that boost the production of an enzyme that helps alter the cells' glucose metabolism. The altered metabolic state, called the Warburg effect, promotes extremely rapid cell proliferation and tumor growth. Adrian Krainer, Ph.D.

23 Jan 2010

A personal account of a heart attack survivor

People would say, myself included, that this can not be true. I had lived my life being active and fit. I had been living a healthful and happy life, trying to set a good example for those around me.

23 Jan 2010

USPTO issues new patent for Advaxis' intellectual property portfolio

The U.S. Patent and Trademark Office (USPTO) issued today patent 7,635,479, "Compositions and Methods for Enhancing the Immunogenicity of Antigens,” by Dr. Yvonne Paterson, et al, which is assigned to the Trustees of the University of Pennsylvania and licensed to Advaxis, Incorporated (OTCBB: ADXS).

22 Jan 2010

Findings offer potential significance to the recovery of walking after spinal cord injury

Researchers at the medical university Karolinska Institutet have created a genetically modified mouse in which certain neurons can be activated by blue light. Shining blue light on brainstems or spinal cords isolated from these mice produces walking-like motor activity. The findings, which are published in the scientific journal Nature Neuroscience, are of potential significance to the recovery of walking after spinal cord injury.

22 Jan 2010

ACS Chemical Biology report supports zebrafish for drug development

By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.

22 Jan 2010

The American Journal of Pathology: Highlights from February 2010 issue

A group led by Dr. Peter Lloyd Jones at the University of Dundee, Dundee, Scotland; the University of Colorado Denver, Aurora, CO; and the University of Pennsylvania, Philadelphia, PA has demonstrated that tenascin-C affects proto-oncogene function in breast cancer. Their report can be found in the February 2010 issue of The American Journal of Pathology.

22 Jan 2010

Postdoctoral scientists receive prestigious award; grants totaling $1.54 million will help in funding innovative projects

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting exceptional early career researchers and innovative cancer research, named 11 new Damon Runyon Fellows at its November 2009 Fellowship Award Committee review.

22 Jan 2010

Researchers identify new therapeutic approach for stroke treatment

For the first time, research led by Youming Lu, PhD, MD, Professor of Neurology and Neuroscience at LSU Health Sciences Center New Orleans School of Medicine, has identified a novel mechanism that may trigger brain damage during stroke and identified a therapeutic approach to block it.

22 Jan 2010

Pioneering research explores possibility of developing mineral enriched flour

Pioneering research combining plant breeding and high-intensity x-rays is being used by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) to explore the possibility of developing wheat which could be used to make potentially life-saving mineral enriched flour.

22 Jan 2010

Understanding mechanism of SIRT6 activity may help treat diabetes and cancer

A study investigating how a cellular enzyme affects blood glucose levels in mice provides clues to pathways that may be involved in processes including the regulation of longevity and the proliferation of tumor cells.

22 Jan 2010

Findings may aid in developing therapeutic drugs for stroke and other neurodegenerative diseases

Biomedical scientists from the University of Central Florida and Louisiana State University have identified a way to block a "cell death signal" that they believe triggers brain damage during strokes.

22 Jan 2010

Celerus Diagnostics demonstrates Rapid ISH on its Wave RPD System

Through collaborative efforts with multiple industry partners, Celerus Diagnostics has successfully demonstrated Rapid ISH™ (in-situ hybridization) on its forthcoming Wave RPD System.

21 Jan 2010

Abaxis' new CRP assay receives FDA marketing clearance

Abaxis, Inc., a medical products company manufacturing point-of-care blood analysis systems, today announced that the U.S. Food and Drug Administration (FDA) has granted 510K marketing clearance of the new C-Reactive Protein (CRP) assay when used by healthcare professionals in conjunction with the Piccolo Xpress™ point-of-care analyzer.

21 Jan 2010

G Protein News and Research

Biogen Idec and Swedish Orphan Biovitrum commence dosing in rFIXFc Phase I/IIa trial for hemophilia B

Researchers identify new gene signature that predicts cancer recurrence in certain breast tumors

Loss of key proteins may account for molecular abnormalities associated with myotonic dystrophy

New technology may allow scientists to monitor real time activity of protein network

Healthy eating trend fuels probiotic yogurt sales

U.S. blood banks have sufficient blood to meet the needs of Haiti victims

Study of 16INK4A gene's role in progression of retinoblastoma

Study: Warburg effect promotes rapid cell proliferation and tumor growth

A personal account of a heart attack survivor

USPTO issues new patent for Advaxis' intellectual property portfolio

Findings offer potential significance to the recovery of walking after spinal cord injury

ACS Chemical Biology report supports zebrafish for drug development

The American Journal of Pathology: Highlights from February 2010 issue

Postdoctoral scientists receive prestigious award; grants totaling $1.54 million will help in funding innovative projects

Researchers identify new therapeutic approach for stroke treatment

Pioneering research explores possibility of developing mineral enriched flour

Understanding mechanism of SIRT6 activity may help treat diabetes and cancer

Findings may aid in developing therapeutic drugs for stroke and other neurodegenerative diseases

Celerus Diagnostics demonstrates Rapid ISH on its Wave RPD System

Abaxis' new CRP assay receives FDA marketing clearance

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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