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Research pinpoints potential new therapeutic target for retinal degeneration

Multi-disciplinary work led by researchers from Trinity College Dublin has pinpointed a potential new therapeutic target for treating retinal degeneration. The work has discovered that a protein (SARM1) involved in neuronal cell injury may also have a role in the progression of retinal degeneration.

20 Apr 2020

Embryonic stem cells commit to specialization surprisingly early

The point when human embryonic stem cells irreversibly commit to becoming specialised has been identified by researchers at the Francis Crick Institute.

17 Apr 2020

Delayed clearance of SARS-CoV2 may explain why men fare worse than women

Researchers at Montefiore Health System and Albert Einstein College of Medicine may have solved a mystery surrounding the novel coronavirus pandemic: Why men infected by the virus generally show more severe symptoms and are more likely than women to die from COVID-19.

17 Apr 2020

Real-time imaging reveals how infiltrating glioma cells alter brain function, blood flow

The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered a side effect of the tumor.

15 Apr 2020

Temple researchers receive NIAID grant to study immunological synapse formation

Switching immune cells on is a critical step in combating infection. In the case of T cells, which are key players in immunity, this happens when dormant T cells circulating in the blood encounter a suspicious agent on the surface of specialized antigen-presenting cells.

14 Apr 2020

Research shows how stress changes structure of the brain

Research led by Si-Qiong June Liu, MD, Ph.D., Professor of Cell Biology and Anatomy at LSU Health New Orleans School of Medicine, has shown how stress changes the structure of the brain and reveals a potential therapeutic target to the prevent or reverse it

14 Apr 2020

Molecular pathway responsible for TNBC's progression and spread identified

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer, a particularly aggressive form of the disease, less than 20% respond.

13 Apr 2020

Study sheds light on how a group of novel organelle-based disorders affects cells

A pioneering study has shed new light on how a group of novel organelle-based disorders affect cells.

10 Apr 2020

Advance in understanding actin sheds light on cell function

Scientists have discovered more about actin, a chemical modification on one of the most abundant and important proteins.

8 Apr 2020

Researchers make breakthrough in unlocking genetic potential of ocean microbes

Researchers have made a breakthrough in developing gene-editing tools to improve understanding of an important ocean microbe.

6 Apr 2020

Therapeutic cooling could mitigate damage to concussed cells

In the future, treating a concussion could be as simple as cooling the brain.

2 Apr 2020

Total-body PET provides suitable images of antibodies up to 30 days after injection

Combining 89Zr-labeled antibodies with total-body positron emission tomography (PET) has extended the utility of novel total-body PET scanners, providing suitable images up to 30 days after the initial injection.

31 Mar 2020

Temple researchers reverse muscle fibrosis associated with overuse injury in animals

Overuse injuries - think muscle strains, tennis elbow, and rotator cuff tears - are a considerable problem in the United States, especially among young athletes.

30 Mar 2020

Study reveals new mechanism underlying organelle communication in brown fat cells

In recent years, brown fat has garnered increasing attention as the so-called good fat that can protect against obesity and associated health risks, like cardiovascular disease and diabetes.

30 Mar 2020

Research could open up new therapeutic strategies for some lung and kidney cancers

New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).

30 Mar 2020

Scientists model human CMV-induced microcephaly using brain organoids

A City of Hope scientist is one step closer to discovering what weakens a pathogen that appears to cause babies to be born with abnormally small heads.

30 Mar 2020

Weakness in lung and kidney cancer cells could serve as therapeutic target

An important discovery about how some cancers rely on glucose to survive could lead to development of tumor-specific treatments.

30 Mar 2020

Berkeley Lights Announces GEPAD to Attack COVID-19 and Other Viruses

Today Berkeley Lights, Inc., announced the GEPAD with the aim to accelerate the discovery of neutralizing antibodies from patient blood samples.

From Bruker Cellular Analysis 26 Mar 2020

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Lonza is a large, multinational corporation serving the entire pharmaceutical product development and manufacturing pipeline, from non-clinical research products to final dosage and delivery solutions.

From Lonza 26 Mar 2020

Changes in surface sugarlike molecules help cancer cells to spread

Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the University of California, Davis. Published March 23 in Proceedings of the National Academy of Sciences, the work could lead to diagnostic tests and new therapies to slow or stop the spread of cancers.

25 Mar 2020