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Branched-chain amino acids in tumors can be targeted to prevent and treat cancer

Researchers at A*STAR's Singapore Bioimaging Consortium have discovered that branched-chain amino acids in tumors can be targeted to prevent and treat cancer. Together with collaborators from the United States and National Cancer Centre Singapore, they found that some cancers potently suppress the catabolism (breakdown) of BCAAs.

21 Jan 2019

Fiderstat could be used as chemopreventative drug for intestinal cancers caused by APC gene mutations

Colorectal Cancer has now become one of the leading causes of death. Studies indicate that smoking, low physical activities and high-fat diet are a major risk factor for colorectal cancer.

21 Jan 2019

Truncal mutations study suggests new direction in origins of cancer

Cancers most commonly arise because of a series of two to five mutations in different genes that combine to cause a tumor.

16 Jan 2019

Poo transplant can successfully treat patients with ulcerative colitis

Poo transplant or "Fecal microbiota transplantation" can successfully treat patients with ulcerative colitis, new research from the University of Adelaide shows.

16 Jan 2019

Scientists find link between colitis and colon cancer

Lingering inflammation in the colon is a known risk factor for colorectal cancer and now scientists report one way it resets the stage to enable this common and often deadly cancer.

14 Jan 2019

University of Cincinnati professor awarded $1.6 million NIAID grant to study Hamburger E. coli

Alison Weiss, PhD, professor in the Department of Molecular Genetics, Biochemistry and Microbiology in UC College of Medicine, has been awarded a four-year grant of $1.6 million from the National Institute of Allergy and Infectious Diseases to study Shiga toxin producing Escherichia coli 0157:H7, also sometimes referred to as Hamburger E. coli.

9 Jan 2019

Colorectal cancer mortality rates predicted to increase globally

In the first effort to predict the future burden of colorectal cancer mortality globally, researchers note that colon and rectal cancer mortality rates are projected to decrease in most countries apart from some Latin American and Caribbean countries, but increases are predicted for several countries from Europe, North America and Oceania.

9 Jan 2019

Novel technique detects new strains of microbes in human fecal microbiota after obesity surgery

Using a unique bioinformatics technique developed at the University of Alabama at Birmingham, UAB researchers have detected the emergence of new strains of microbes in the human fecal microbiota after obesity surgery.

9 Jan 2019

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

Johns Hopkins researchers have identified a protein involved in cell proliferation and the development of new blood vessels that could serve as a marker for the early detection of colorectal cancers.

7 Jan 2019

First viable mouse model of Hirschsprung's disease developed

About one in every 5,000 babies is born without enteric neurons in distal colon resulting in Hirschsprung's disease. Because of the lacking neurons, contents of the gut cannot pass normally resulting in constipation and enlargement of colon.

7 Jan 2019

Risk of heart attack and stroke is high in the months before cancer diagnosis, shows study

Older adults with cancer are more likely to have had a heart attack or stroke in the months prior to their cancer diagnosis compared with similar adults who do not have cancer during the same period, according to a report published online today in Blood. Lung and colon cancers, as well as advanced-staged cancers, appear to be most strongly associated with an elevated risk of heart attack and stroke caused by blood clots in the arteries.

24 Dec 2018

Researchers find new way to cut the power of tumors

Instead of tackling tumors head-on, an international team of researchers from the University of Geneva and the Amsterdam UMC, location VUmc in Amsterdam has chosen to regulate their vascularization by intervening with cellular receptor that is overexpressed specifically in cancer blood vessels.

20 Dec 2018

IASLC’s ELIC pilot project develops innovative technique for improving early lung cancer detection

Evidence proves that screening saves lives, with screening for breast, colon, prostate and cervical cancers, for example, being accepted in many parts of the world as a routine part of medical care.

20 Dec 2018

New test shown to be 100% effective at detecting cervical cancer

Researchers have developed a new cervical cancer test that proved to be 100% effective at detecting the cancer in a trial of 15,744 participants.

19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

Scientists create patient-specific model to identify most effective treatment for appendix cancer

Scientists at the Wake Forest Institute for Regenerative Medicine have recently developed a process that may change the way cancer of the appendix is treated in the future.

17 Dec 2018

New 'epigenetics-based' cervical cancer test outperforms Pap smear and HPV tests

A new test for cervical cancer was found to detect all of the cancers in a randomized clinical screening trial of 15,744 women, outperforming both the current Pap smear and human papillomavirus test at a reduced cost, according to a study led by Queen Mary University of London.

17 Dec 2018

Ten year follow-up after negative colonoscopy related to reduced risk of colorectal cancer

Ten years after a negative colonoscopy, Kaiser Permanente members had 46 percent lower risk of being diagnosed with and were 88 percent less likely to die from colorectal cancer compared with those who did not undergo colorectal cancer screening, according to a study published today in JAMA Internal Medicine.

17 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Excess weight responsible for cancers globally finds report

According to a new report published this week, excess body weight is one of the major reasons behind cancers worldwide. The report written by scientists at the American Cancer Society (ACS) and published in the journal CA: A Cancer Journal for Clinicians shows that 3.9 percent of the cases of cancers were linked to excess body weight and this amounted to 544,300 cases in 2012.

16 Dec 2018

Colon News and Research

Branched-chain amino acids in tumors can be targeted to prevent and treat cancer

Fiderstat could be used as chemopreventative drug for intestinal cancers caused by APC gene mutations

Truncal mutations study suggests new direction in origins of cancer

Poo transplant can successfully treat patients with ulcerative colitis

Scientists find link between colitis and colon cancer

University of Cincinnati professor awarded $1.6 million NIAID grant to study Hamburger E. coli

Colorectal cancer mortality rates predicted to increase globally

Novel technique detects new strains of microbes in human fecal microbiota after obesity surgery

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

First viable mouse model of Hirschsprung's disease developed

Risk of heart attack and stroke is high in the months before cancer diagnosis, shows study

Researchers find new way to cut the power of tumors

IASLC’s ELIC pilot project develops innovative technique for improving early lung cancer detection

New test shown to be 100% effective at detecting cervical cancer

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Scientists create patient-specific model to identify most effective treatment for appendix cancer

New 'epigenetics-based' cervical cancer test outperforms Pap smear and HPV tests

Ten year follow-up after negative colonoscopy related to reduced risk of colorectal cancer

Researchers reveal how key transcription factor keeps the immune system in check

Excess weight responsible for cancers globally finds report

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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