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Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Optibrium Ltd, a leading developer of software for drug discovery, today announced the release of the latest version of StarDrop™, its comprehensive software platform for small molecule design, optimisation, and data analysis.

From Optibrium Ltd. 2 Mar 2022

Estimating life expectancy changes since 2020

Researchers investigated LE in 29 countries, including most European countries, Chile, and the USA, in 2021.

1 Mar 2022

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different spatial scales.

28 Feb 2022

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Insilico Medicine, an end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that it has dosed multiple healthy volunteers in Phase I clinical trial evaluating ISM001-055, the first anti-fibrotic small molecule inhibitor generated by Insilico's AI-powered drug discovery platform for idiopathic pulmonary fibrosis (IPF).

24 Feb 2022

MIT chemists develop a novel way to synthesize himastatin

Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.

24 Feb 2022

Real-time imaging shows cells of developing fruit fly eye move into position

The ability of cells to self-organize into specific patterns in tissues that serve a function is a universal feature of life.

23 Feb 2022

Outcomes of phase 3 clinical trial of CVO PLUS CURATIF capsules for COVID-19 treatment

A phase 3 randomized clinical trial has recently been conducted to investigate the efficacy of a capsule formulation in treating mild-to-moderate COVID-19 patients.

23 Feb 2022

The logic that controls gene regulation in human cells discovered

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge can be applied to, for example, investigating cancers and other genetic diseases.

21 Feb 2022

European research project focuses on fighting against new psychoactive drugs

Promoting the fight against the use of drugs of abuse, anticipating to the appearance of new psychoactive drugs and assessing the risks these have on human health are the main objectives of the European research project approved by the European Commission and led by the Research Group on Neuropsychopharmacology of Amphetamine Derivatives of the University of Barcelona.

21 Feb 2022

Poll: Most parents have limited knowledge about CBD products for children

Products containing cannabidiol (CBD), a chemical compound naturally found in marijuana and hemp, have been used in recent years to help adults manage medical issues like chronic pain and mood disorders.

21 Feb 2022

N-glycosylation blockers reduce SARS-CoV-2 infection

A new Virology study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity.

20 Feb 2022

Structure of protein that can pump toxic molecules out of bacterial cells revealed

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple antibiotics.

18 Feb 2022

New research shines light on mysterious dynamics that define the interplay between nerves and muscle

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

Respiratory virus particles likely travel greater distance than previously thought

A modeling study raises questions about how far respiratory droplets, like those that transmit the virus that causes COVID-19, can travel before becoming harmless.

16 Feb 2022

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers select and study an RDV-resistant virus by serial passaging of wild type SARS-CoV-2 in the presence of increasing concentrations of RDV.

15 Feb 2022

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A novel combination treatment approach extended survival in mice with pancreatic cancer, demonstrating a potential second-line therapy for patients, according to findings published in Proceedings of the National Academy of Sciences.

15 Feb 2022

Researchers overcome key challenge in creating sulfur-based medicines

A key technical challenge in creating new sulfur-based medicines has been overcome by scientists at Nanyang Technological University, Singapore (NTU Singapore), leading to the prospect of many new therapeutic 'weapons' in the fight against disease and illness.

15 Feb 2022

Nitazoxanide shows promise for COVID-19 treatment in animal model

In a recent study posted to the bioRxiv* pre-print server, researchers demonstrated that Nitazoxanide (NTZ), an oral drug, broadly inhibits replication of several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in preclinical models of infection.

13 Feb 2022

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

A study in mice - led by researchers at Washington University School of Medicine in St. Louis - shows that a new class of compounds the scientists developed can improve multiple aspects of metabolic syndrome.

12 Feb 2022

Compound News and Research

Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Estimating life expectancy changes since 2020

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

MIT chemists develop a novel way to synthesize himastatin

Real-time imaging shows cells of developing fruit fly eye move into position

Outcomes of phase 3 clinical trial of CVO PLUS CURATIF capsules for COVID-19 treatment

The logic that controls gene regulation in human cells discovered

European research project focuses on fighting against new psychoactive drugs

Poll: Most parents have limited knowledge about CBD products for children

N-glycosylation blockers reduce SARS-CoV-2 infection

Structure of protein that can pump toxic molecules out of bacterial cells revealed

New research shines light on mysterious dynamics that define the interplay between nerves and muscle

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Respiratory virus particles likely travel greater distance than previously thought

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

Researchers overcome key challenge in creating sulfur-based medicines

Nitazoxanide shows promise for COVID-19 treatment in animal model

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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