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Longevity gene offers hope for children with progeria

A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.

15 Oct 2025

UC Irvine develops human-like colon model for precision medicine

Researchers at the University of California, Irvine have developed a 3D human colon model integrated with bioelectronics to aid in colorectal cancer research and drug discovery.

15 Oct 2025

LGBTQ+ adolescents face higher rates of mental health challenges and substance use

New research from the University of Delaware finds that LGBTQ+ adolescents in Delaware face strikingly higher rates of mental health challenges and substance use compared to their peers.

15 Oct 2025

Low-dose steroids show promise for treating severe kidney inflammation

Will it be possible to treat severe kidney inflammation with fewer drugs in the future? A new study by the University Hospital Bonn (UKB), the University of Bonn, and the University of Hamburg gives cause for hope.

15 Oct 2025

CRISPR therapy shows promise against influenza in human lung chips

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

15 Oct 2025

SGLT-2 inhibitors offer protection against autoimmune conditions

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group of diabetes drugs called sulfonylureas, finds a study from South Korea published by The BMJ today.

15 Oct 2025

Targeting bacterial communication may offer antibiotic-free wound therapy

Researchers at University of California San Diego School of Medicine have discovered a previously unrecognized mechanism by which Staphylococcus aureus - one of the most common causes of skin and soft tissue infections worldwide - delays wound healing.

15 Oct 2025

GLP-1 medications found to slow alcohol absorption and lessen intoxication

There's mounting evidence that popular drugs prescribed for diabetes management and weight loss - better known by trade names like Ozempic and Wegovy - could be effective in reducing alcohol use.

15 Oct 2025

Combination therapy shows promising results in patients with rare subtype of non-Hodgkin lymphoma

Combining an epigenetic therapy with an anti-PD-1 antibody, which uses the body's natural response to viral infections, showed promising results in patients with relapsed or refractory natural killer/T-cell lymphoma (R/R NKTL), a rare and aggressive cancer with limited treatment options.

15 Oct 2025

Global drug addiction mortality rates double despite fewer new cases

The global drug use disorder deaths have more than doubled since 1990, even as new addiction cases declined, highlighting a widening gap in harm reduction and treatment access, especially in wealthy nations.

15 Oct 2025

In Mississippi, Medicaid coverage of weight loss drugs fails to catch on

April Hines has battled with her weight since she was a teenager. But in the past couple of years, she's fallen from 600 pounds to 385, and her blood pressure and blood sugar levels are down, too. "I'm not as fatigued as I used to be, and I've been able to go back to church," she said.

15 Oct 2025

Discovery of CPD gene mutations sheds light on rare congenital hearing loss

Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing loss, an international team of researchers has discovered.

14 Oct 2025

Study explores how losing the Y chromosome fuels bladder cancer aggressiveness

University of Arizona Cancer Center researchers will study the potential effects of the loss of the Y chromosome in the development and progression of bladder cancer thanks to a grant of up to $6.5 million over seven years from the National Cancer Institute.

14 Oct 2025

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.

14 Oct 2025

Common hospice medications may carry major unintended risks for people with dementia

Hospice care aims to bring comfort, peace, and dignity to patients at the end of life. Yet for the growing number of Americans with dementia who enter hospice, their course is often long and unpredictable - making it especially important to ensure treatments align with each person's goals and stage of illness.

14 Oct 2025