Neurodegenerative Diseases News and Research

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Researchers explore how a small change in protein shape causes long-term consequences

Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.

19 May 2020

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Canadian Glycomics Network welcomes $16.3 million renewed funding from NCE

The Networks of Centres of Excellence recently announced its continued support in Canadian glycomics research with a three-year investment of $16.3 million through the Canadian Glycomics Network (GlycoNet).

15 May 2020

New imaging device can help detect early biomarker of Alzheimer’s disease

Biomedical engineers at Duke University have devised a new imaging device capable of measuring both the thickness and texture of the various layers of the retina at the back of the eye.

15 May 2020

Repurposed drug normalizes body weight, reverses metabolic damage in obese mice

An off-label experiment in mice using disulfiram, which has been used to treat alcohol use disorder for more than 50 years, consistently normalized body weight and reversed metabolic damage in obese middle-aged mice of both sexes.

14 May 2020

Study shows COVID-19 vulnerability is highly dependent on host genetic architecture

A new US study available on the preprint server medRxiv reveals certain genetic variations that are associated with infection susceptibility and diverse clinical presentation of coronavirus disease (COVID-19) – including asymptomatic cases and severe forms of the disease in younger patients.

10 May 2020

Researchers shed new light on the structure of RNA

Australian and US researchers have made a breakthrough in understanding the structure of a key genetic molecule, called RNA, and revealing for the first time how these changes impact RNA's function.

7 May 2020

Study investigates potential use of metal catalysts to create drug discovery platform

The use of metals in drug delivery could offer major benefits, including allowing for lower dosages of a medication to achieve therapeutic effects.

6 May 2020

New breakthrough may help cure prion disease

A molecular biologist at the University of Massachusetts Amherst who has for decades studied the nightmarish group of fatal diseases caused by prions - chronic wasting disease in deer, mad cow in cattle and its human analog - credits a middle-of-the-night dream for a crucial insight, a breakthrough she hopes could lead to a cure.

6 May 2020

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases.

6 May 2020

Study shows thinking and walking speed usually decline together

Do thinking and walking go hand in hand in determining the health course of senior adults? A study published by UT Health San Antonio researchers found that, indeed, the two functions often parallel each other in determining a person's health trajectory.

6 May 2020

New technology enables visualization of small structures inside whole cells and tissues

Since Robert Hooke's first description of a cell in Micrographia 350 years ago, microscopy has played an important role in understanding the rules of life.

4 May 2020

Scientists identify two genes that regulate healthy fat levels in mice

Salk and Scripps Research Institute scientists, along with collaborators at the pharmaceutical company Lundbeck, identified two genes that can regulate levels of healthy fats, called FAHFAs, in mice.

4 May 2020

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

In recognition of his high-impact work advancing the field of RNA-targeting medicines, the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, has awarded Scripps Research Chemistry Professor Matthew Disney, PhD, a prestigious Research Program Award, to aid Disney's development of treatments for incurable diseases such as Alzheimer's, Parkinson's, ALS and frontotemporal dementia.

4 May 2020

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

In this interview, Dr. Polinski and Dr. Atabakhsh discuss the importance of developing biomarkers for Parkinson’s and the partnership between MJFF and Abcam.

From Abcam 1 May 2020

Nanodevices could prevent plaque formation in the brain

Alzheimer's disease is the sixth leading cause of death in the United States, affecting one in 10 people over the age of 65. Scientists are engineering nanodevices to disrupt processes in the brain that lead to the disease.

30 Apr 2020

Computational techniques offer a better understanding of amyloid fibril growth, brain pathology

As physicians and families know too well, though Alzheimer's disease has been intensely studied for decades, too much is still not known about molecular processes in the brain that cause it.

30 Apr 2020

CZI announces grants for researchers studying the role of inflammation in disease

Today, the Chan Zuckerberg Initiative announced $14 million in funding to support 29 interdisciplinary teams and build a network of researchers that will explore emerging ideas regarding the role of inflammation in disease.

29 Apr 2020

Researchers identify a new risk factor for multiple neurodegenerative diseases

Scientists at the HudsonAlpha Institute for Biotechnology, the University of California, San Francisco (UCSF), and the University of Alabama at Birmingham (UAB), have identified a new risk factor for multiple neurodegenerative diseases.

28 Apr 2020

Study reveals how general anesthesia works

Hailed as one of the most important medical advances, the discovery of general anesthetics - compounds which induce unconsciousness, prevent control of movement and block pain - helped transform dangerous and traumatic operations into safe and routine surgery.

27 Apr 2020

Neurodegenerative Diseases News and Research

Researchers explore how a small change in protein shape causes long-term consequences

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

Canadian Glycomics Network welcomes $16.3 million renewed funding from NCE

New imaging device can help detect early biomarker of Alzheimer’s disease

Repurposed drug normalizes body weight, reverses metabolic damage in obese mice

Study shows COVID-19 vulnerability is highly dependent on host genetic architecture

Researchers shed new light on the structure of RNA

Study investigates potential use of metal catalysts to create drug discovery platform

New breakthrough may help cure prion disease

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

Study shows thinking and walking speed usually decline together

New technology enables visualization of small structures inside whole cells and tissues

Scientists identify two genes that regulate healthy fat levels in mice

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

Nanodevices could prevent plaque formation in the brain

Computational techniques offer a better understanding of amyloid fibril growth, brain pathology

CZI announces grants for researchers studying the role of inflammation in disease

Researchers identify a new risk factor for multiple neurodegenerative diseases

Study reveals how general anesthesia works

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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