Protein C News and Research

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New approach targets cell surface protein to treat leukemia and solid tumors

In 2021, research led by Ryan Flynn, MD, PhD, and his mentor, Nobel laureate Carolyn Bertozzi, PhD, opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs.

23 Apr 2025

DT-109 shows promise in treating atherosclerosis and liver disease

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis - a primary driver of cardiovascular death worldwide - in large mammals, a study suggests.

23 Apr 2025

Marstacimab approved to treat patients aged 12 years and above (weighing at least 35 kg) with hemophilia A or B

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved the medicine marstacimab (Hympavzi) to prevent or reduce bleeding in patients 12 years of age and older weighing at least 35 kg with hemophilia A and B.

23 Apr 2025

Insights into Raman spectroscopy as a bioprocess analytical technique

Dr. Nimesh Khadka discusses Raman spectroscopy's role in bioprocess monitoring, highlighting its advantages in molecular specificity and real-time analysis.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 23 Apr 2025

Tulane researchers identify a potential new way to treat idiopathic pulmonary fibrosis

Researchers at Tulane University have identified a potential new way to treat idiopathic pulmonary fibrosis (IPF), a deadly and currently incurable lung disease that affects more than 3 million people worldwide.

22 Apr 2025

Study reveals how medulloblastoma spreads and grows on the leptomeninges

Researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps medulloblastoma, the most prevalent malignant brain tumor in children, spread and grow on the leptomeninges, the membranes surrounding the brain and spinal cord.

22 Apr 2025

Walnut consumption linked to reduced inflammation and lower colon cancer risk

There are new findings out about the benefits of eating walnuts. Results from a UConn School of Medicine clinical trial on the cover of the April edition of the journal Cancer Prevention Research show walnuts improve systemic inflammation while also reducing colon cancer risk.

22 Apr 2025

Machine learning unlocks millions of safer CRISPR enzymes for gene editing

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

22 Apr 2025

Age and sex shape Alzheimer’s blood biomarkers, study finds

ESTHER study found that non-modifiable factors like age, sex, and APOE ε4 status significantly influence blood biomarker levels linked to Alzheimer’s disease. GFAP and NfL levels, in particular, showed strong age- and sex-related patterns, with GFAP levels rising faster in women.

22 Apr 2025

New study sheds light on 3D gene hubs driving brain cancer

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell Medicine researchers.

22 Apr 2025

Boost your transfection success with these proven expert tips

Gain expert insights in this interview on achieving transfection success. Explore proven strategies to optimize your approach and enhance results.

From Sartorius 22 Apr 2025

Major breakthrough could turn IV drugs into oral treatments for brain cancer and Alzheimer's

A research team led by scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) made a major breakthrough with the potential to turn IV drugs into oral treatments for diseases like brain cancer and Alzheimer's disease.

21 Apr 2025

Researchers find immune system proteins involved in severe cases of schistosomiasis

New insights into the mechanisms that cause more severe cases of schistosomiasis - a disease caused by parasitic worms and second only to malaria in terms of potential harm - have been revealed by researchers at Penn State.

21 Apr 2025

Engineered brain cells offer new hope for treating Alzheimer's

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to University of California, Irvine scientists.

21 Apr 2025

Fruit fly study reveals key brain proteins that help prevent seizures

One in ten people will have at least one seizure in their life, but effective treatments for seizures remain very limited, in part due to incomplete understanding of the brain mechanisms involved.

21 Apr 2025

Ursolic acid modulates estrogen conversion to alleviate MASLD inflammation

The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) has been escalating annually, positioning it as the leading cause of chronic liver disease worldwide.

21 Apr 2025

Cellular bridges aid axon growth after spinal cord damage

Capitalizing on the flexibility of tiny cells inside the body's smallest blood vessels may be a powerful spinal cord repair strategy, new research suggests.

21 Apr 2025

Muscle building unaffected by vegan or animal-based protein sources

A new study asked three questions about muscle protein synthesis in response to a nine-day diet and weight training regimen: First, does the source of protein - plant or animal-based - make any difference to muscle gain? Second, does it matter if total daily protein intake is evenly distributed throughout the day? And third, does a moderate but sufficient daily protein intake influence any of these variables? The answer to all three questions is "no," the researchers found.

21 Apr 2025

Researchers uncover genetic link between autism spectrum disorder and myotonic dystrophy type 1

Scientists from The Hospital for Sick Children (SickKids) and University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition called myotonic dystrophy type 1 (DM1).

21 Apr 2025

New therapeutic frontiers in the management of achondroplasia

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular mechanisms and therapeutic interventions for achondroplasia, the most common form of genetic dwarfism.

20 Apr 2025