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New engineered peptides could prevent the superbug crisis

A recent study reports the development of a synthetic antibacterial peptide PLG0206.

22 Sep 2022

Public-private collaboration receives grant for research on microbiota-boosted cancer therapy

Health~Holland has awarded close to € 800,000 to a public-private partnership between UMC Utrecht, Artizan Biosciences, Inc. (USA) and MicroViable Therapeutics (Spain) to unravel how the intestinal microbiota can be exploited to boost cancer immunotherapy and limit therapy side-effects.

21 Sep 2022

Humanized zebrafish could aid in the search for MS drugs

The zebrafish should be known to many aquarium enthusiasts mainly because of its striking pigmentation. However, the characteristic black-blue stripes, to which the animal owes its name, only form over time.

20 Sep 2022

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Mohsan Saeed, PhD, assistant professor of biochemistry at Boston University School of Medicine (BUSM), has received a five-year, $2 million R35 grant from the National Institute of General Medical Sciences, as well as a five-year, $2.5 million R01 grant from the National Institute of Allergy and Infectious Diseases.

20 Sep 2022

Is aspirin linked to higher rates of survival for cancer patients?

Researchers discussed the existing evidence on the use of acetylsalicylic acid (aspirin) in cancer treatment.

19 Sep 2022

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational Medicine, researchers in the United States designed a bivalent coronavirus disease 2019 (COVID-19) vaccine on the messenger ribonucleic acid (mRNA) platform.

18 Sep 2022

Study explores the impact of genetic risk variants on overall disease burden and healthy life years

In a new study, researchers explored the genetic risk factors associated with various diseases to understand their impact on healthy life years.

14 Sep 2022

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib remain poorly understood. In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells.

14 Sep 2022

Age-related changes in microbiome composition affects brain macrophages

Scientists review the impact of age-related gut microbiome composition on age-associated diseases caused by dysfunctional macrophages within the brain.

13 Sep 2022

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* server, researchers in Singapore and the United States demonstrated that intranasal (I.N.) delivery of a mucosal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination triggered a superior T cell response compared to an equivalent dose of antigen delivered by the subcutaneous (S.C.) route.

12 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

Self-replicating intradermal RNA vaccine against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers assessed the efficiency of a controllable self-replicating ribonucleic acid (c-srRNA) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Sep 2022

All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

Plants and plant-derived preparations as co-treatments for COVID-19

A recent Journal of Medicinal Food study proposed a comprehensive guideline for applying plants and plant-derived formulations to co-treat severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and other viral infections.

8 Sep 2022

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

A newly developed agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease, signaling its promise as a potential treatment for the disease, according to a team of researchers at UTHealth Houston.

8 Sep 2022

Scientists develop a model human gut microbiome

A team of US-based scientists has developed a novel bacterial community comprising 119 microbial species naturally found in the human body. The study is published in the journal Cell.

7 Sep 2022

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

Vivo Surgical, a pioneering medical device company based in Singapore, has become the first start-up to win the prestigious WIPO-IPOS IP for Innovation Award for 2022

7 Sep 2022

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

Vivo Surgical, a pioneering medical device company based in Singapore, has become the first start-up to win the prestigious WIPO-IPOS IP for Innovation Award for 2022. Now in its 10th year, this award celebrates Singaporean companies that have achieved outstanding growth through the successful application of intangible assets and intellectual property.

From Vivo Surgical 7 Sep 2022

The role of nasal microbiome in Parkinson's disease

A recent study provides an overview of how the nasal bacterial population influences olfactory processing and neurodegeneration.

5 Sep 2022

New and unique technique to brain imaging has potential to save lives

Observing the brain without creating any breaks in the skull is an emerging technology for those studying various brain-related diseases.

5 Sep 2022

in vivo News and Research

New engineered peptides could prevent the superbug crisis

Public-private collaboration receives grant for research on microbiota-boosted cancer therapy

Humanized zebrafish could aid in the search for MS drugs

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Is aspirin linked to higher rates of survival for cancer patients?

An improved COVID-19 vaccine shows promise against Omicron in experimental models

Study explores the impact of genetic risk variants on overall disease burden and healthy life years

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

Age-related changes in microbiome composition affects brain macrophages

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

Study identifies new therapeutic target against lung adenocarcinoma

Self-replicating intradermal RNA vaccine against SARS-CoV-2

All SARS-CoV-2 variants neutralized by a potent new antibody

Plants and plant-derived preparations as co-treatments for COVID-19

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

Scientists develop a model human gut microbiome

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

The role of nasal microbiome in Parkinson's disease

New and unique technique to brain imaging has potential to save lives

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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