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Scientists succeed in growing functional salivary gland

A research group led by scientists from Showa University and the RIKEN Center for Biosystems Dynamics Research in Japan have, for the first time, succeeded in growing three-dimensional salivary gland tissue that, when implanted into mice, produced saliva like normal glands.

11 Oct 2018

A new way to create customized mouse models for studying brain development

Scientists studying how genetics impact brain disease have long sought a better experimental model. Cultures of genetically-modified cell lines can reveal some clues to how certain genes influence the development of psychiatric disorders and brain cancers.

11 Oct 2018

Common gene variants linked to migraine risk in African-American children

Pediatric researchers have discovered common gene variants associated with migraines in African-American children.

11 Oct 2018

Researchers design modeling system to infer relationships between genes, drugs, and their environment

A team of researchers at the Icahn School of Medicine at Mount Sinai and the University of Washington has designed a modeling system that integrates genomic and temporal information to infer causal relationships between genes, drugs, and their environment, allowing for a more accurate prediction of their interactions over time.

11 Oct 2018

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Anthony Fitzpatrick, PhD, a Principal Investigator at Columbia's Zuckerman Institute and Columbia University Irving Medical Center, together with scientists from the Mayo Clinic and Boston Children's Hospital, has been awarded $11.3 million to map the three-dimensional structures of protein tangles that accumulate in the human brain.

11 Oct 2018

Research team awarded $3.6 million to assess safety of genome editing

As genome editing technologies quickly advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. They are also bringing to light a number of challenges that need to be addressed before potential treatments can be widely used in patients.

11 Oct 2018

UK Biobank provides wealth of information for further genetic studies

There are 3.2 billion positions on the human genome and it requires a study of huge number of genetic variations in the populations to estimate the associations between genetic disorders and mutations. Two new studies have been published in the journal Nature.

11 Oct 2018

Molecular mechanisms behind therapeutic action of ancient herbal medicine discovered

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for a therapeutic action of an ancient herbal medicine used across Africa to treat various illnesses, including epilepsy.

10 Oct 2018

Growth of early brain circuits may help predict child's intelligence and emotional health

Growth rates of brain circuits in infancy may help experts predict what a child's intelligence and emotional health could be when the child turns 4, a new study has found.

10 Oct 2018

Chromosomal instability may predict which patients will respond better to colorectal cancer drug

Researchers at RCSI, along with international collaborators within the ANGIOPREDICT research consortium, have discovered that chromosomal instability (where whole human chromosomes or parts of chromosomes are duplicated or deleted) may predict which patients will receive most benefit from a key drug used to treat colorectal cancer (Avastin).

10 Oct 2018

Molecular pathways underlying myopia open new ways for drug development

Myopia (nearsightedness) and hyperopia (farsightedness) develop through different molecular pathways, according to a new study publishing October 9 in the open-access journal PLOS Biology by Andrei Tkatchenko of Columbia University and colleagues.

10 Oct 2018

Phase 2 results on tazemetostat EZH2 inhibitor to be presented at ESMO 2018

Epizyme, Inc., a clinical-stage company developing novel epigenetic therapies, announced today that updated efficacy and safety data from the fully enrolled cohort of epithelioid sarcoma (ES) patients in its ongoing Phase 2 trial of tazemetostat will be presented in a poster discussion session at the European Society for Medical Oncology (ESMO) 2018 Congress to be held October 19-23 in Munich, Germany.

10 Oct 2018

Co-Diagnostics awarded patent related to its CoPrimer platform technology

Co-Diagnostics, Inc., a molecular diagnostics company with a unique, proprietary platform for the development of molecular diagnostic tests, announced today that it has been awarded a patent from the United States Patent and Trademark Office related to the Company's CoPrimer™ platform technology.

10 Oct 2018

Gene types that drive racial disparities in myeloma identified

Researchers at Mayo Clinic have identified three specific gene types that account for a known two-to-three-fold increase in myeloma diagnoses among African-Americans.

10 Oct 2018

New AUC published for lumbar puncture and spinal fluid analysis in Alzheimer's diagnosis

In preparation for more tools that detect and measure the biology associated with Alzheimer's and other dementias earlier and with more accuracy, an Alzheimer's Association-led Workgroup has published appropriate use criteria for lumbar puncture (spinal tap) and spinal fluid analysis in the diagnosis of Alzheimer's disease.

10 Oct 2018

Discovery of gene mutation could offer benefit for people suffering from diabetes, heart disease, obesity

Researchers say they have discovered a gene mutation that slows the metabolism of sugar in the gut, giving people who have the mutation a distinct advantage over those who do not.

10 Oct 2018

Female birds become more promiscuous after hatchings fail in the first breeding attempt

Females of a socially monogamous passerine, the Japanese great tit (Parus minor), become more promiscuous after hatchings fail in the first breeding attempt -- apparently attempting to ensure successful reproduction.

10 Oct 2018

Bug that causes stomach cancer may increase risk of colorectal cancers

A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers.

10 Oct 2018

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

New research on autism has found, in a mouse model, that drug treatment at a young age can reverse social impairments. But the same intervention was not effective at an older age.

10 Oct 2018

New mobile apps may simplify complex genomic and biome data

Spurred by the rapidly expanding use of in-home tests for "omic" - genomic and microbiomic - data for humans, pets, and even homes themselves, university researchers have begun tackling the difficult challenge of making the results interactive and understandable to non-experts.

10 Oct 2018

Genetic News and Research

Scientists succeed in growing functional salivary gland

A new way to create customized mouse models for studying brain development

Common gene variants linked to migraine risk in African-American children

Researchers design modeling system to infer relationships between genes, drugs, and their environment

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Research team awarded $3.6 million to assess safety of genome editing

UK Biobank provides wealth of information for further genetic studies

Molecular mechanisms behind therapeutic action of ancient herbal medicine discovered

Growth of early brain circuits may help predict child's intelligence and emotional health

Chromosomal instability may predict which patients will respond better to colorectal cancer drug

Molecular pathways underlying myopia open new ways for drug development

Phase 2 results on tazemetostat EZH2 inhibitor to be presented at ESMO 2018

Co-Diagnostics awarded patent related to its CoPrimer platform technology

Gene types that drive racial disparities in myeloma identified

New AUC published for lumbar puncture and spinal fluid analysis in Alzheimer's diagnosis

Discovery of gene mutation could offer benefit for people suffering from diabetes, heart disease, obesity

Female birds become more promiscuous after hatchings fail in the first breeding attempt

Bug that causes stomach cancer may increase risk of colorectal cancers

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

New mobile apps may simplify complex genomic and biome data

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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