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Scientists discover new mechanism that explains role of EBV in tumor growth

The Epstein-Barr virus (EBV), a virus of the herpes family, has two distinct life phases: After infecting a cell it first goes into a resting phase. Under certain circumstances the virus can become active - and then induces tumor growth or promotes its synthesis in the cell.

18 Jan 2010

Scientists manipulate and expand the number of stem/progenitor cells

Scientists at Fred Hutchinson Cancer Research Center have cleared a major technical hurdle to making umbilical-cord-blood transplants a more widely-used method for treating leukemia and other blood cancers.

18 Jan 2010

Research reveals gene activation is linked to most aggressive type of brain cancer

Glioblastoma (GBM), the brain cancer better known for having killed Senator Ted Kennedy a few months ago, is the most aggressive and lethal of all brain tumours.

18 Jan 2010

HHMI: Distinct cancer-causing mutations in neighboring cells can cooperate to produce tumors

According to modern biology textbooks, a single genetic mutation is rarely enough to cause cancer. It is generally thought that cells must accumulate a series of mutations that work together to trigger tumor development.

18 Jan 2010

Researchers uncover novel genetic markers for diabetes-related traits

In two major studies published in Nature Genetics today, researchers use biological understanding to dissect the genetics of diabetes. An international team comprising researchers from more than 100 institutions analysed vast suites of genetic data from more than 100,000 people of European descent to uncover the associations.

18 Jan 2010

Three proteins that lead to memory loss associated with Alzheimer's disease identified

A scientific group led by the Translational Genomics Research Institute (TGen) have identified three kinases, or proteins, that dismantle connections within brain cells, which may lead to memory loss associated with Alzheimer's disease.

18 Jan 2010

Findings could pave way for new therapeutic approaches for Friedreich's ataxia

Elevated levels of DNA damage have for the first time been found in the cellular mitochondria and nuclei of patients with the inherited, progressive nervous system disease called Friedreich's ataxia (FRDA), says a multicenter research team led by an expert from the University of Pittsburgh Cancer Institute (UPCI).

18 Jan 2010

M. D. Anderson researchers discover mechanism that helps glioblastomas evade immune attack

Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from The University of Texas M. D. Anderson Cancer Center report in a paper featured on the cover of the Jan. 15 issue of Clinical Cancer Research.

18 Jan 2010

Scientists discover new links between inherited blindness and AHI1 gene

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine have discovered new links between a common form of inherited blindness affecting children and a gene known as Abelson helper integration site-1 (AHI1).

18 Jan 2010

New class of drugs could help prevent skin cancer

A new study by Loyola University Health System researchers could lead to alternative treatments that would shrink skin cancer tumors with drugs. The drugs would work by turning on a gene that prevents skin cells from becoming cancerous, said senior author Mitchell Denning, Ph.D.

18 Jan 2010

Multimmune GmbH and Boulder Diagnostics partner to develop HSP70 lateral flow point of care test

Multimmune GmbH and Boulder Diagnostics Inc. announce today the joint development of an HSP70 lateral flow point of care test. Multimmune has discovered that many tumor types display the heat shock protein 70 (Hsp70) on the cell surface.

13 Jan 2010

Work provides new insight into potential therapeutic treatments for cancer diseases

An enzyme that normally helps break down stored fats goes into overdrive in some cancer cells, making them more malignant, according to new findings by a team at The Scripps Research Institute.

13 Jan 2010

Findings may pave way for significant advancements in cochlear implant technology for hearing loss

Loss of spiral ganglion neurons or hair cells in the inner ear is the leading cause of congenital and acquired hearing impairment. Researchers at the University of California, San Diego, School of Medicine and the National Institutes of Health found that Sox2, a protein that regulates stem cell formation, is involved in spiral ganglion neuron development. The study was published in the January 13 issue of the Journal of Neuroscience.

13 Jan 2010

Olfactory dysfunction may serve as an early diagnostic tool for Alzheimer's disease

A study published in the January 13, 2010 issue of the Journal of Neuroscience links a loss of smell function in Alzheimer's disease (AD) model animals with amyloid β (protein) accumulation in the brain, a distinguishing hallmark of Alzheimer's disease. Research conducted by NYU Langone Medical Center suggests that olfactory dysfunction, a common symptom of AD, may serve as an early diagnostic tool for the disease.

13 Jan 2010

University of Leicester study provides new insights into preventer and reliever treatments for asthma

A new study at the University of Leicester is probing why asthma relief inhalers might actually make asthma worse- and what can be done about it.

13 Jan 2010

Synta Pharmaceuticals presents preclinical results of STA-9090 at AACR-IASLC Joint Conference

Synta Pharmaceuticals Corp. (NASDAQ: SNTA), a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that preclinical results presented at the AACR-IASLC (American Academy of Cancer Research – International Association for the Study of Lung Cancer) Joint Conference based on work done at Synta and at the Dana-Farber Cancer Institute in Boston showed that STA-9090, a potent, synthetic inhibitor of heat shock protein 90 (Hsp90), demonstrated potent activity against 100% of all non-small cell lung cancer cell lines tested, including those with EGFR, HER2 or KRAS mutations including the EGFR T790 mutation that is present in roughly 50% of cases of erlotinib or gefitinib resistance.

13 Jan 2010

Studies show naturally-occurring protein in humans restores motor function in rats after a stroke

People with impaired mobility after a stroke soon may have a therapy that restores limb function long after the injury, if a supplemental protein works as well in humans as it does in paralyzed rats.

13 Jan 2010

GIND scientists identify major role of TDP-43 in two neurodegenerative diseases

Scientists at the Gladstone Institute of Neurological Disease (GIND) have identified the reason a key protein plays a major role in two neurodegenerative diseases.

13 Jan 2010

Scientists discover new protein function that helps control cell behavior

Carnegie Mellon University's Philip R. LeDuc and his collaborators in Massachusetts and Taiwan have discovered a new function of a protein that could ultimately unlock the mystery of how these workhorses of the body play a central role in the mechanics of biological processes in people.

13 Jan 2010

Research suggests variation of CETP gene is linked to lowered risk of dementia and AD

Preliminary research suggests that variation of a gene for a plasma protein is associated with slower age-related memory decline and a lower risk of dementia and Alzheimer disease (AD), according to a study in the January 13 issue of JAMA.

13 Jan 2010

G Protein News and Research

Scientists discover new mechanism that explains role of EBV in tumor growth

Scientists manipulate and expand the number of stem/progenitor cells

Research reveals gene activation is linked to most aggressive type of brain cancer

HHMI: Distinct cancer-causing mutations in neighboring cells can cooperate to produce tumors

Researchers uncover novel genetic markers for diabetes-related traits

Three proteins that lead to memory loss associated with Alzheimer's disease identified

Findings could pave way for new therapeutic approaches for Friedreich's ataxia

M. D. Anderson researchers discover mechanism that helps glioblastomas evade immune attack

Scientists discover new links between inherited blindness and AHI1 gene

New class of drugs could help prevent skin cancer

Multimmune GmbH and Boulder Diagnostics partner to develop HSP70 lateral flow point of care test

Work provides new insight into potential therapeutic treatments for cancer diseases

Findings may pave way for significant advancements in cochlear implant technology for hearing loss

Olfactory dysfunction may serve as an early diagnostic tool for Alzheimer's disease

University of Leicester study provides new insights into preventer and reliever treatments for asthma

Synta Pharmaceuticals presents preclinical results of STA-9090 at AACR-IASLC Joint Conference

Studies show naturally-occurring protein in humans restores motor function in rats after a stroke

GIND scientists identify major role of TDP-43 in two neurodegenerative diseases

Scientists discover new protein function that helps control cell behavior

Research suggests variation of CETP gene is linked to lowered risk of dementia and AD

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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