Immune System News and Research

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A new strategy to protect against HIV infection

An effective vaccine against HIV-1 remains elusive, but one promising strategy focuses on designer antibodies that have much broader potency than most normal, exquisitely specific antibodies.

29 Mar 2013

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

Exosomes can transfer membrane proteins, study reveals

Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting discovery that means these tiny vehicles could one day be loaded with therapeutic agents, such as RNA interference, and directly target disease-carrying cells.

28 Mar 2013

CureVac begins CV9104 Phase 2b clinical trial in patients with castration-resistant prostate cancer

CureVac GmbH, a clinical stage biopharmaceutical company that has pioneered the development of a new class of therapies and vaccines based on messenger RNA, today announced that it has initiated a double-blind, randomized Phase 2b clinical trial of its RNActive cancer vaccine, CV9104, for the treatment of patients with castration-resistant prostate cancer.

28 Mar 2013

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

Merck, known as MSD outside the United States and Canada, today announced that the Biologics License Application for its investigational Timothy grass pollen (Phleum pratense) allergy immunotherapy tablet has been accepted for review by the U.S. Food and Drug Administration.

28 Mar 2013

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

The Bellvitge Biomedical Research Institute has signed a licensing agreement with the Spanish biotech company Histocell to make use of a patent for the treatment of acute pulmonary diseases with mesenchymal stem cells.

28 Mar 2013

Study links genetic variation, wheezing illness to childhood asthma risk

About 90 percent of children with two copies of a common genetic variation and who wheezed when they caught a cold early in life went on to develop asthma by age 6, according to a study to be published March 28 by the New England Journal of Medicine.

28 Mar 2013

Novel molecular mechanism can prevent aging and cancer progression, say researchers

University of Montreal researchers have discovered a novel molecular mechanism that can potentially slows the aging process and may prevent the progression of some cancers.

27 Mar 2013

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

Early diagnosis is critical in treating Lyme disease. However, nearly one quarter of Lyme disease patients are initially misdiagnosed because currently available serological tests have poor sensitivity and specificity during the early stages of infection.

27 Mar 2013

Study provides important insight into how BMT treatment works in patients with MS

A new study by Multiple Sclerosis researchers at three leading Canadian centres addresses why bone marrow transplantation has positive results in patients with particularly aggressive forms of MS.

27 Mar 2013

Scientists discover novel compounds that can lead to new strategies for treating diseases

Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.

26 Mar 2013

Presence of certain bacteria in stomach microbiota can prevent pathology from H. pylori

Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of print in the journal Infection and Immunity.

26 Mar 2013

New vaccine proves highly effective against H5N1 virus

Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza.

26 Mar 2013

Eating behavior could act as defense mechanism against infections and autoimmune disorders

Neurons that control hunger in the central nervous system also regulate immune cell functions, implicating eating behavior as a defense against infections and autoimmune disease development, Yale School of Medicine researchers have found in a new study published in the Proceedings of the National Academy of Sciences (PNAS).

26 Mar 2013

Novel cell therapy effective in treating aggressive form of childhood leukemia

Two children with an aggressive form of childhood leukemia had a complete remission of their disease—showing no evidence of cancer cells in their bodies—after treatment with a novel cell therapy that reprogrammed their immune cells to rapidly multiply and destroy leukemia cells.

26 Mar 2013

Two studies shed light on molecular biology of three blood disorders

Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.

26 Mar 2013

Researchers rejuvenate mice’s blood by reversing blood-producing stem cells

The blood of young and old people differs. In an article published recently in the scientific journal Blood, a research group at Lund University in Sweden explain how they have succeeded in rejuvenating the blood of mice by reversing, or re-programming, the stem cells that produce blood.

25 Mar 2013

High-fiber foods can fight inflammation

Inflammation is the body's normal response to injury. While it may be a natural defense system, it can lead to disease development if it becomes chronic. A University of Alabama at Birmingham (UAB) expert says one way to fight inflammation is with food.

25 Mar 2013

Researchers expand hematopoietic stem cells for bone marrow transplantation

More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.

25 Mar 2013

$Immune system responds to fracture in similar way as to infection$

Immune system responds to fracture in similar way as to infection

Researchers at Charité - Universitätsmedizin Berlin have succeeded in demonstrating an association between delayed bone fracture healing and increased concentration of specific immune cells in the blood of the patient.

25 Mar 2013

Immune System News and Research

A new strategy to protect against HIV infection

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Exosomes can transfer membrane proteins, study reveals

CureVac begins CV9104 Phase 2b clinical trial in patients with castration-resistant prostate cancer

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

Study links genetic variation, wheezing illness to childhood asthma risk

Novel molecular mechanism can prevent aging and cancer progression, say researchers

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

Study provides important insight into how BMT treatment works in patients with MS

Scientists discover novel compounds that can lead to new strategies for treating diseases

Presence of certain bacteria in stomach microbiota can prevent pathology from H. pylori

New vaccine proves highly effective against H5N1 virus

Eating behavior could act as defense mechanism against infections and autoimmune disorders

Novel cell therapy effective in treating aggressive form of childhood leukemia

Two studies shed light on molecular biology of three blood disorders

Researchers rejuvenate mice’s blood by reversing blood-producing stem cells

High-fiber foods can fight inflammation

Researchers expand hematopoietic stem cells for bone marrow transplantation

Immune system responds to fracture in similar way as to infection

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