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Quitting smoking with rimonabant

Using selective cannabinoid 1 (CB1) receptor antagonists such as rimonabant at a dose of 20 mg per day can help people quit smoking, can help them to remain abstinent, and can help prevent the weight gain that so often accompanies attempts at stopping smoking.

18 Jul 2007

Novel type of communication between nerve cells in the brain discovered

The findings may have relevance for the prevention and treatment of epilepsy, and possibly in the exploration of other aspects of brain functions, from creative thought processes to mental illnesses such as schizophrenia.

17 Jul 2007

Src inhibitors may prove beneficial in breast cancer therapy

Estrogen, which binds estrogen receptor alpha (ER-alpha), is a risk factor for breast cancer development.

13 Jul 2007

Genes play a large role in sour taste perception

Scientists at the Monell Chemical Senses Center report that genes play a large role in determining individual differences in sour taste perception.

12 Jul 2007

Senomyx issued new U.S. patent for "T1R taste receptors and genes encoding same"

Senomyx, Inc. has announced the issuance by the U.S. Patent and Trademark Office of U.S. Patent No. 7,241, 880, "T1R Taste Receptors and Genes Encoding Same."

12 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

New insights into acute promyelocytic leukemia

Results from two new studies provide key mechanistic insights into the complex molecular events that cause a deadly type of leukemia.

10 Jul 2007

Scientists take exciting approach for attacking cancers

A new study identifies a combination therapy that may sensitize human cancer cells to a promising treatment currently being used in clinical trials.

10 Jul 2007

African-Americans women more likely to present with later stage and higher grade breast cancer tumors compared to Caucasians

African-American women are diagnosed with more advanced breast cancer than Caucasians, according to a new, single hospital study.

10 Jul 2007

Breast cancers to be more aggressive in African-American women

A study of more than 2,200 women at the Kimmel Cancer Center at Jefferson in Philadelphia shows that African American women have more advanced breast cancer at the time of diagnosis than Caucasian women.

10 Jul 2007

Postmenopausal Asian women who eat a Western diet at greater risk of developing breast cancer

Postmenopausal Asian women who eat a "meat-sweet" or Western diet are at greater risk of developing breast cancer than those who eat a "vegetable-soy" diet, according to a new study. The findings mark the first time an association between a Western diet and breast cancer has been identified in Asian women.

10 Jul 2007

Racial differences in severity of breast cancer presentation confirmed

African-American women are diagnosed with more advanced breast cancer than Caucasians, according to a new, single hospital study.

10 Jul 2007

Scientists discover protein instrumental to brain development and repair

Scientists at Children's National Medical Center have demonstrated conclusively that a specific protein and its signaling activity are instrumental in myelination and remyelination, processes essential to the creation and repair of the brain's white matter.

9 Jul 2007

Trastuzumab and chemo improves survival in women with operable HER-2 positive breast cancer

A recent meta-analysis of five major breast cancer trials has confirmed that combination treatment with the antibody trastuzumab and chemotherapy improves survival in women with operable HER-2 positive breast cancer.

9 Jul 2007

Rimonabant may prevent and treat obesity-related liver disease

A new study on the effect of the anti-obesity drug rimonabant on liver function in obese rats found that it reduced markers of liver damage, decreased levels of pro-inflammatory proteins, and improved lipid profiles.

4 Jul 2007

Lung cancer patients taking Tarceva who develop a rash fair better

The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals, Inc.

4 Jul 2007

Fibrinogen protein may inhibit spinal cord regeneration

Fibrinogen, a blood-clotting protein found in circulating blood, has been found to inhibit the growth of central nervous system neuronal cells, a process that is necessary for the regeneration of the spinal cord after traumatic injury.

4 Jul 2007

Discovery of two effective antibodies for SARS

An international team of investigators has identified the first human antibodies that can neutralize different strains of the virus responsible for outbreaks of severe acute respiratory syndrome (SARS).

4 Jul 2007

Human immune system in a test tube

Surgical instruments or implants that are contaminated with residual bacteria, or pyrogens, can cause blood poisoning in patients. Researchers are developing a test that imitates the human immune system in the laboratory, eliminating the need for animal experiments.

4 Jul 2007

Skin rash actually signifies better outcomes for pancreatic and lung cancer patients

The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals, Inc.

3 Jul 2007