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Human microbiome metabolites enhance colon injury by enterohemorrhagic E. coli, study shows

It remains mysterious why humans get infected by some bacterial or viral pathogens relatively easily while animals that have very similar tissues and immune functions do not.

20 Mar 2019

Researchers discover previously unknown mechanism by which cells can sense oxygen

Researchers from the University of Oulu and Harvard University have found a previously unknown mechanism by which cells in the body sense oxygen. Lack of oxygen had a direct influence on the functioning of genes, and prevented cell differentiation.

20 Mar 2019

FDA warns two breast implant makers for failure to comply with post-approval study requirements

Today, the U.S. Food and Drug Administration issued warning letters to two breast implant manufacturers for failure to comply with their requirements, under their premarket approval orders, to conduct post-approval studies to assess the long-term safety and risks of their silicone gel-filled breast implants.

20 Mar 2019

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Androgens, commonly known as male hormones, stimulate prostate cancer cells to grow. Thus, many of the drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor. This standard treatment is known as androgen deprivation therapy.

20 Mar 2019

Roundworm study suggests alternatives for treatment of schizophrenia

A group of Brazilian scientists have long conducted experiments with roundworms to investigate the role of schizophrenia-linked genes in patients' response to antipsychotic drugs. The results obtained thus far point to new ways of understanding resistance to certain classes of medication.

20 Mar 2019

FDA approves first drug for treatment of postpartum depression in adult women

The U.S. Food and Drug Administration today approved Zulresso (brexanolone) injection for intravenous use for the treatment of postpartum depression in adult women. This is the first drug approved by the FDA specifically for PPD.

20 Mar 2019

ECDC-WHO report: TB remains a major public health challenge in the European region

The latest ECDC-WHO report Tuberculosis surveillance and monitoring in Europe 2019 (2017 data) shows that despite an overall decline in numbers of people suffering from TB, the disease remains a major public health challenge in the Region.

20 Mar 2019

Newly discovered parameters offer more control over efficient release of drugs

Researchers at Eindhoven University of Technology and Utrecht University have discovered the parameters that govern the encapsulation of drugs. This gives more control over the slow and steady release of drugs in patients.

20 Mar 2019

FDA warns marketer of unapproved products claiming to treat addiction, chronic pain

The U.S. Food and Drug Administration today posted a warning letter to Nutra Pharma Corp. for illegally marketing unapproved products labeled as homeopathic with claims about their ability to treat addiction and chronic pain, including pain associated with cancer, diabetes, shingles, fibromyalgia and other serious conditions.

19 Mar 2019

Cholesterol lowering drug can also help treat cancer-associated cachexia

Brazilian researchers have discovered that a drug regularly prescribed to control cholesterol can also be used to treat cachexia, or wasting syndrome, a condition characterized by rapid weight loss and muscle atrophy associated with extreme physical weakness.

19 Mar 2019

Researchers identify origin of chronic pain in humans

A new study by researchers at The University of Texas at Dallas, UT MD Anderson Cancer Center, UT Health Science Center at Houston and Baylor College of Medicine has produced evidence of the source of chronic pain in humans, revealing several new targets for pain treatment.

19 Mar 2019

New class of drugs could help treat patients diagnosed with ovarian cancer

A team of researchers across The University of Manchester have shown that a new class of drugs are able to stop ovarian cancer cells growing.

19 Mar 2019

Fish consumption can help prevent asthma, study reveals

A scientist from James Cook University in Australia says an innovative study has revealed new evidence that eating fish can help prevent asthma.

19 Mar 2019

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

The Global Antibiotic Research and Development Partnership and Evotec AG are today announcing the formation of a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance.

19 Mar 2019

New electronic support system for choosing drug treatment based on patient’s genotype

The science of pharmacogenomics (PGx) studies how genetic variability affects an individual’s response to a drug. Most patients metabolize a medication as expected. But some eliminate it from the body before it can do its work, while others process it slowly, causing it to build up in the body and risk an overdose.

19 Mar 2019

Scientists identify brain circuit responsible for cocaine-seeking behavior during relapse

Approximately 1.5 million Americans use cocaine in a given year, according to the National Institute on Drug Abuse. Many are repeat users. Unfortunately, there are currently no FDA-approved medicinal treatments for cocaine addiction.

19 Mar 2019

Study shows ticagrelor is equally safe and effective as clopidogrel after heart attack

Patients given clot busters to treat a heart attack fared equally well if they were given the standard blood thinning medication clopidogrel versus the newer, more potent drug ticagrelor, according to research presented at the American College of Cardiology's 68thAnnual Scientific Session.

19 Mar 2019

Common medications to treat heartburn linked to increased risks for kidney failure

Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study.

19 Mar 2019

Scientists reverse alcohol-seeking behavior in rats with flip of a switch

Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats--with the flip of a switch.

19 Mar 2019

TGen and ABL sign agreement to distribute new TB test technology

n an important step toward eradicating tuberculosis, the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has signed a licensing agreement with an international biomedical firm, Advanced Biological Laboratories, to market and distribute TGen's patented Next Generation Sequencing-based TB test technology.

19 Mar 2019

Drugs News and Research

Human microbiome metabolites enhance colon injury by enterohemorrhagic E. coli, study shows

Researchers discover previously unknown mechanism by which cells can sense oxygen

FDA warns two breast implant makers for failure to comply with post-approval study requirements

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Roundworm study suggests alternatives for treatment of schizophrenia

FDA approves first drug for treatment of postpartum depression in adult women

ECDC-WHO report: TB remains a major public health challenge in the European region

Newly discovered parameters offer more control over efficient release of drugs

FDA warns marketer of unapproved products claiming to treat addiction, chronic pain

Cholesterol lowering drug can also help treat cancer-associated cachexia

Researchers identify origin of chronic pain in humans

New class of drugs could help treat patients diagnosed with ovarian cancer

Fish consumption can help prevent asthma, study reveals

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

New electronic support system for choosing drug treatment based on patient’s genotype

Scientists identify brain circuit responsible for cocaine-seeking behavior during relapse

Study shows ticagrelor is equally safe and effective as clopidogrel after heart attack

Common medications to treat heartburn linked to increased risks for kidney failure

Scientists reverse alcohol-seeking behavior in rats with flip of a switch

TGen and ABL sign agreement to distribute new TB test technology

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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