Immune System News and Research

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Combined complement mutations affect individuals' risk of aHUS and prognosis

Certain gene mutations affect individuals' risk of developing a serious kidney condition, as well as their prognosis after being diagnosed with the disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

22 Feb 2013

Vanderbilt investigators report new insights into workings of calprotectin

On the front lines of our defenses against bacteria is the protein calprotectin, which "starves" invading pathogens of metal nutrients. Vanderbilt investigators now report new insights to the workings of calprotectin - including a detailed structural view of how it binds the metal manganese.

22 Feb 2013

Researchers identify second B-cell attachment receptor for Epstein-Barr virus

Epstein-Barr virus (EBV) affects more than 90 percent of the population worldwide and was the first human virus found to be associated with cancer. Now, researchers from Beth Israel Deaconess Medical Center (BIDMC) have broadened the understanding of this widespread infection with their discovery of a second B-cell attachment receptor for EBV.

21 Feb 2013

FDA approves new vial size for CSL Behring’s Privigen to treat primary immunodeficiency

CSL Behring today announced that the United States Food and Drug Administration has approved a 40 g (400 mL) vial size for Privigen, immune globulin intravenous [human].

21 Feb 2013

Imatinib can relieve and slow down progression of multiple sclerosis

A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study published in PLOS ONE.

21 Feb 2013

Sixth death from novel coronavirus recorded in Britain

"A British man infected with a new virus from the same family as SARS has died, health officials said on Tuesday, bringing the worldwide death toll from the previously unknown disease to six," Reuters reports.

21 Feb 2013

Supreme Court gives FTC more power to police hospital mergers

The decision is a win for the federal government as it seeks to monitor the trend toward consolidations around the country.

21 Feb 2013

NIAID-funded Phase I trial to evaluate two related candidate vaccines against shigellosis

Researchers have launched an early-stage human clinical trial of two related candidate vaccines to prevent infection with Shigella, bacteria that are a significant cause of diarrheal illness, particularly among children.

21 Feb 2013

Immune Pharmaceuticals commences Phase II study with bertilimumab to treat ulcerative colitis

Immune Pharmaceuticals Ltd., a privately held Israeli company, and EpiCept Corporation announced today that Immune is initiating, following authorization from Israeli health authorities, a Phase II double-blind placebo controlled study with its lead drug, bertilimumab, in patients with moderate-to-severe ulcerative colitis.

21 Feb 2013

Immunotherapy could be answer to treating novel coronavirus

Investigation into the mechanism of action of the novelcoronavirus HCoV-EMC, which recently emerged in the Middle East, has revealed that although human bronchial epithelia are very susceptible to infection with the virus, interferon I and III were both able to significantly reduce its replication in cell culture.

20 Feb 2013

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

ADCs are used for a new type of targeted therapy that consists of a specific anti-cancer antibody or antibody fragment linked to a potent anti-cancer therapeutic.

20 Feb 2013

Internationally-recognized cancer clinician named first K. Hasumi Professor of Medical Oncology

Internationally-recognized cancer clinician and researcher Takami Sato, M.D., Ph.D., who serves as the Director of the Metastatic Uveal Melanoma Program in the Department of Medical Oncology at Thomas Jefferson University, has been named the first K. Hasumi Professor of Medical Oncology.

20 Feb 2013

Study demonstrates function of newly discovered regulatory mechanism of myeloid cells in cancer

Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer.

20 Feb 2013

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.

20 Feb 2013

Scientists create new strain of polio to protect vaccine factory workers

"Scientists have created new strains of polio intended to protect workers in factories that make polio vaccine," the New York Times reports.

20 Feb 2013

New coronavirus could potentially be treated with immunotherapy

The new coronavirus that has emerged in the Middle East is well-adapted to infecting humans but could potentially be treated with immunotherapy, according to a study to be published on February 19 in mBio-, the online open-access journal of the American Society for Microbiology.

20 Feb 2013

SARS-linked virus well adapted to infect humans, could be treated with drugs to boost immune system, study shows

"A new virus that emerged in the Middle East last year and has killed five people is well adapted to infecting humans but could potentially be treated with drugs that boost the immune system, scientists said on Tuesday," Reuters reports, noting, "The virus, called novel coronavirus or NCoV, is from the same family as the common cold and as SARS, or Severe Acute Respiratory Syndrome."

19 Feb 2013

Loyola proposes new subspecialty to diagnose and treat patients with depression, heart disease

A Loyola University Medical Center psychiatrist is proposing a new subspecialty to diagnose and treat patients who suffer both depression and heart disease. He's calling it "Psychocardiology."

19 Feb 2013

Interleukin-10 levels predict otitis media culprit

Research shows that high serum levels of interleukin-10 indicate that the likely cause of acute otitis media is infection with Streptococcus pneumoniae, as opposed to Haemophilus influenzae or Moraxella catarrhalis.

18 Feb 2013

Study describes pharmacological action of TZDs directly on pancreas

A scientific study published on the journal Diabetes, edited by the American Diabetes Association, describes for the first time the pharmacological action of thiazolidinediones (TZDs) —anti-diabetic drugs— directly on pancreas, the organ which produces insulin.

18 Feb 2013

Immune System News and Research

Combined complement mutations affect individuals' risk of aHUS and prognosis

Vanderbilt investigators report new insights into workings of calprotectin

Researchers identify second B-cell attachment receptor for Epstein-Barr virus

FDA approves new vial size for CSL Behring’s Privigen to treat primary immunodeficiency

Imatinib can relieve and slow down progression of multiple sclerosis

Sixth death from novel coronavirus recorded in Britain

Supreme Court gives FTC more power to police hospital mergers

NIAID-funded Phase I trial to evaluate two related candidate vaccines against shigellosis

Immune Pharmaceuticals commences Phase II study with bertilimumab to treat ulcerative colitis

Immunotherapy could be answer to treating novel coronavirus

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

Internationally-recognized cancer clinician named first K. Hasumi Professor of Medical Oncology

Study demonstrates function of newly discovered regulatory mechanism of myeloid cells in cancer

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Scientists create new strain of polio to protect vaccine factory workers

New coronavirus could potentially be treated with immunotherapy

SARS-linked virus well adapted to infect humans, could be treated with drugs to boost immune system, study shows

Loyola proposes new subspecialty to diagnose and treat patients with depression, heart disease

Interleukin-10 levels predict otitis media culprit

Study describes pharmacological action of TZDs directly on pancreas

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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