Immune System News and Research

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Anti-ghrelin vaccine decreases food intake and increases calorie burning in mice

A new therapeutic vaccine to treat obesity by suppressing the appetite-stimulating hormone ghrelin decreases food intake and increases calorie burning in mice, a new study finds. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

New skin cancer drug brings hope

A new drug for the dreaded cancer melanoma is in the horizon. It is called Vemurafenib. This is a class of drug that cancer researchers are applauding today at the American Society of Clinical Oncology's annual meeting in Chicago.

5 Jun 2011

Scientists use super microscope to pinpoint body’s immunity ‘switch’

Using the only microscope of its kind in Australia, medical scientists have been able for the first time to see the inner workings of T-cells, the front-line troops that alert our immune system to go on the defensive against germs and other invaders in our bloodstream.

5 Jun 2011

DFG to form new collaborative research centers as of 1 July 2011

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish 21 new Collaborative Research Centres (CRCs) as of 1 July 2011. This was decided by the relevant Grants Committee at its spring meeting in Bonn.

4 Jun 2011

Results from HSPPC-96 Phase 2 study against recurrent gliobastoma presented at ASCO 2011

In data presented at The American Society of Clinical Oncology (ASCO) Annual Meeting, cancer researchers found that the brain tumor vaccine HSPPC-96 for treating recurrent gliobastoma (GBM) has a favorable safety profile and extends survival by two to three times more than the current median survival rate.

4 Jun 2011

GW researchers demonstrate Mta1 gene's role in survival of schistosomes

By using mice lacking a crucial gene that controls the process of chromatin remodeling of cytokines including those responsible for inflammation and comparing them to normal wild type mice with the gene, researchers at the George Washington University School of Medicine and Health Sciences have shown that the gene, Mta1, is essential for the parasite Schistosoma haematobium to establish a productive infection and survival in the host.

4 Jun 2011

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Atherosclerosis is the most common cause of cardiovascular disease, and results from chronic inflammation of arterial vessel walls. An international collaboration led by Professor Christian Weber of Ludwig-Maximilians-Universität (LMU) in Munich and Privatdozentin Alma Zernecke of Würzburg University now shows that dendritic cells stimulate this process by derailing a mechanism that normally acts as a brake on immune reactions.

4 Jun 2011

Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

For patients with advanced melanoma, which is the most lethal type of skin cancer, the results of a large clinical trial show that a vaccine combined with the immune-boosting drug Interleukin-2 can improve response rate and progression-free survival.

4 Jun 2011

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

A new therapy for type 1 diabetes? A promising treatment for deadly viruses? Does a common treatment for children with severe infection actually cause more harm than good? These are important questions being investigated by pediatric researchers at Mattel Children's Hospital UCLA.

4 Jun 2011

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have demonstrated why certain immune cells chronically exposed to HIV shut down, and how they can be reactivated.

4 Jun 2011

FSU assistant professor unlocks mysteries of KSHV infection

In the early days of the AIDS epidemic, a once-rare form of cancer known as Kaposi's sarcoma emerged as a frequent harbinger of HIV. Its stigma was best illustrated by Tom Hanks, who portrayed a gay man trying to conceal the cancerous skin lesions from his co-workers in the 1993 movie "Philadelphia."

4 Jun 2011

Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

A duo of drugs, each targeting a prime survival strategy of tumors, can be safely administered and are potentially more effective than either drug alone for advanced, inoperable melanomas, according to a phase 1 clinical trial led by Dana-Farber Cancer Institute investigators.

4 Jun 2011

Cancer vaccine shows improved response rate in patients

A vaccine for one of the most lethal cancers, advanced melanoma, has improved response rate and progression-free survival for patients when combined with the immunotherapy drug Interleukin-2, according to research led by scientists from The University of Texas MD Anderson Cancer Center and Indiana University Health Goshen Center for Cancer Care.

3 Jun 2011

Mimicry allows bacteria to evade host's defense responses

Deadly bacteria may be evolving antibiotic resistance by mimicking human proteins, according to a new study by the Translational Genomics Research Institute (TGen).

3 Jun 2011

Lung-sparing surgery, photodynamic therapy improve survival of mesothelioma patients

Pleural mesothelioma patients who undergo lung-sparing surgery in combination with photodynamic therapy (PDT) show superior overall survival than patient treated using the conventional therapy of extrapleural pneumonectomy (EPP) with PDT, indicates new research from the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania.

3 Jun 2011

APC8015F investigational vaccine improves survival of prostate cancer patients

Metastatic prostate cancer patients who received an investigational vaccine made from their own frozen immune cells lived 10 months longer than those not treated with it, according to data being presented by researchers from the Kimmel Cancer Center at Jefferson at the 2011 American Society of Clinical Oncology annual meeting in Chicago on Saturday, June 4.

3 Jun 2011

New approach for identifying 'self' proteins targeted in autoimmune diseases

Researchers from Harvard Medical School and MIT have developed a new approach for identifying the "self" proteins targeted in autoimmune diseases such as multiple sclerosis, diabetes and rheumatoid arthritis.

3 Jun 2011

Positive interim results from iBio's H1N1 influenza subunit vaccine Phase 1 trial

iBio, Inc. today announced positive interim results from a Phase 1 clinical trial of an iBioLaunch platform-produced subunit vaccine directed against Influenza A/California/04/09 (H1N1).

3 Jun 2011

Scientists identify protein sorting mechanism used by salivary gland

University of Louisville researchers are one step closer to helping millions of people whose salivary glands no longer work because of disease or damage from treatment of diseases.

3 Jun 2011

Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

One of the beneficial compounds found in green tea has a powerful ability to increase the number of "regulatory T cells" that play a key role in immune function and suppression of autoimmune disease, according to new research in the Linus Pauling Institute at Oregon State University.

3 Jun 2011

Immune System News and Research

Anti-ghrelin vaccine decreases food intake and increases calorie burning in mice

New skin cancer drug brings hope

Scientists use super microscope to pinpoint body’s immunity ‘switch’

DFG to form new collaborative research centers as of 1 July 2011

Results from HSPPC-96 Phase 2 study against recurrent gliobastoma presented at ASCO 2011

GW researchers demonstrate Mta1 gene's role in survival of schistosomes

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

FSU assistant professor unlocks mysteries of KSHV infection

Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

Cancer vaccine shows improved response rate in patients

Mimicry allows bacteria to evade host's defense responses

Lung-sparing surgery, photodynamic therapy improve survival of mesothelioma patients

APC8015F investigational vaccine improves survival of prostate cancer patients

New approach for identifying 'self' proteins targeted in autoimmune diseases

Positive interim results from iBio's H1N1 influenza subunit vaccine Phase 1 trial

Scientists identify protein sorting mechanism used by salivary gland

Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

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